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  • 1
    Electronic Resource
    Electronic Resource
    Progress and Current Status in Research on Nanostructured Cu-Ag Microcomposites for Conductor Wires (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 539-543 (Mar. 2007), p. 2798-2803 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: An overview of the microstructure evolution, mechanical properties, electrical conductivity and microalloyingis presented and some further research fields are suggested for Cu-Ag microcomposites. The nanostructures offilamentary morphology in these microcomposites can be obtained by heavy deformation. Both the mechanical andelectrical properties depend upon the material composition, strain degree, intermediate heat treatments and finalannealing processes. These factors strongly affect the phase proportion, microstructure morphology, precipitate volume,hardening level and filamentary distribution. Optimum technology of materials preparation makes the microcompositespossess high strength and conductivity. Some third constituents added to the alloys improve the strength but generallydecrease the conductivity. It is considered that relative mechanisms and processes should be further investigated for thedevelopment and application of the microcomposites
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/15/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.539-543.2798.pdf
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  • 2
    Electronic Resource
    Electronic Resource
    Refined localization of a punctate palmoplantar keratoderma gene to a 5·06-cM region at 15q22.2–15q22.31 (2005)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 152 (2005), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  Punctate palmoplantar keratoderma (PPK) is a rare autosomal dominant cutaneous disorder characterized by numerous hyperkeratotic papules distributed on the palms and soles. Two loci for punctate PPK were recently found to be located on 8q24.13–8q24.21 and 15q22–15q24. However, no genes for this disease have been identified to date.Objectives  To refine the previously mapped regions and to identify the disease gene locus in a four-generation Chinese family with punctate PPK.Methods  Genetic linkage analysis was carried out in this family using microsatellite markers on chromosomes 8q and 15q. Two-point linkage analysis was performed using Linkage programs version 5·10 and the haplotype was constructed using Cyrillic version 2·02 software.Results  We failed to confirm our previous locus at 8q24.13–8q24.21, but significant evidence for linkage was observed in the region of 15q with a maximum two-point LOD score of 5·38 at D15S153 (θ = 0·00). Haplotype analysis localized the punctate PPK locus within the region defined by D15S651 and D15S988. This region overlaps by 5·06 cM with the previously reported punctate PPK region.Conclusions  This study refines a disease gene causing punctate PPK to a 5·06-cM interval at 15q22.2–15q22.31.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.2005.06488.x
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  • 3
    Electronic Resource
    Electronic Resource
    The genetic epidemiology of alopecia areata in China (2004)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 151 (2004), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  Alopecia areata (AA) is hypothesized to be an organ-specific autoimmune disease with genetic predisposition and an environmental trigger. There are few clinical data in Asians.Objectives  To describe the genetic epidemiological features of AA patients in China and to determine the possible genetic model for AA.Methods  Data for 1032 patients with AA were obtained by questionnaire in the Institute of Dermatology of Anhui Medical University in China from 2001 to 2003. Complex segregation analysis and heritability analysis were performed using Falconer's method, EPI INFO 6·0 and SAGE-REGTL programs.Results  In total, 1032 AA patients (male/female ratio 1·1 : 1) were enrolled, representing 0·94% of the total number of cases seen in our outpatient clinic during that time. The mean ± SD age of onset was 28·98 ± 13·43 years. The difference between the mean age of onset in males and females was not significant. Most patients (82·6%) experienced their first episode of AA within the first four decades of life. A positive family history of AA was obtained in 87 patients (8·4%). The prevalence of AA in first-, second- and third-degree relatives of the proband with AA was 1·6%, 0·19% and 0·03%, respectively. These figures were higher than those in controls. A greater severity and longer duration of AA were seen in the early onset group than in the late-onset group. The early onset group also had more affected first- and second-degree relatives. The heritability of AA in first-, second- and third-degree relatives was 47·16%, 42·53% and 22·29%, respectively. Based on the REGTL results, the best model was a polygenic additive model for AA.Conclusions  The effect of genetic factors is strong in AA, but environmental factors such as infection and psychological stress may still play an important role. Our findings on the genetics of AA are consistent with a polygenic additive mode of inheritance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.2004.05915.x
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  • 4
    Electronic Resource
    Electronic Resource
    Electromagnetic calorimeter with thin gap wire chambers
    Amsterdam : Elsevier
    Nuclear Instruments and Methods in Physics Research Section A: 351 (1994), S. 330-335 
    Details
    ISSN: 0168-9002
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0168-9002(94)91360-9
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