ISSN:
1432-1076
Keywords:
Chromosome deletion
;
Chromosomes 16–18
;
Familial and genetic mental retardation
;
Familial and genetic translocation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The 18q- syndrome is described in a mother and her daughter. In both of them an identical, apparently balanced 18q-/14p+ translocation was found (Karyotype: 46,XX,t(14;18)(p11;q21)), suggesting that chromosomal material was lost in the process of translocation. The segment deleted and responsible for the 18q- phenotype must be located in or near band 18q21, in which the break is assumed to have occurred.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00455265
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