ISSN:
1052-9306
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Amino acid methyl esters were condensed with 1,3-dichloro-1,1,3,3-tetrafluoroacetone to yield the corresponding oxazolidinone derivatives whose electron capture negative ion methane chemical ionization mass spectra were studied. Anions corresponding to [M + CI]-, (HCI2)- and (CF2CI)2CO)- are discussed in relation to their appearance in the amino acid oxazolidinone spectra. Other common fragmentation modes were the elimination of stable neutral molecules (HCI, HF, CO2) in various combinations from the molecular anion. Aliphatic amino acids having a γ-hydrogen atom relative to the oxazolidinone ring carbonyl group gave an anionic fragment formally equivalent to the McLafferty rearrangement product of positive ion electron impact mass spectrometry.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bms.1200120707
Permalink