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  • 1
    ISSN: 1279-8517
    Keywords: Shoulder ; Supraspinatus outlet syndrome ; Computed tomography ; Mineralization ; Subacromial space
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Une réduction de l'espace sous-acromial et une augmentation de la pression sous-acromiale avait été considérées comme jouant un rôle très important dans la pathogénie des lésions de la coiffe des rotateurs. L'objectif de cette étude est de développer une méthode basée sur la tomodensitométrie, pour mesurer la distance acromio-humérale et la minéralisation de la partie inférieure de l'acromion. Chez 7 patients avec une rupture unilatérale de la coiffe des rotateurs et deux avec un syndrome de conflit, des images acquises en coupes axiales transverses étaient obtenues avec une section d'épaisseur de 1 mm en situation de relaxation musculaire dans une position standard. Les structures osseuses étaient ensuite reconstruites en trois dimensions, la distance minimale verticale entre l'acromion et l'humérus était déterminée sur trois images frontales des deux côtés. La distribution de la minéralisation à l'intérieur de la surface caudale de l'acromion était évaluée en utilisant une méthode d'ostéo-absorptiométrie. Bien que le score de Constant était significantivement réduit chez les épaules malades, l'épaisseur de l'espace sous-acromial n'était pas systématiquement plus bas que du côté controlatéral. Dans 7 cas, les zones de minéralisation maximale de l'acromion étaient identiques dans les deux épaules et dans 2 cas étaient plus basses du côté affecté. Cette étude préliminaire suggère qu'avec la relaxation musculaire, un amincissement de l'espace sous-acromial ne peut pas être détecté sur des images de reconstruction frontale, par tomodensitométrie tridimensionnelle et qu'un potentiel d'accroissement de la pression subacromiale n'est pas assez élevé pour causer une augmentation de la densité osseuse de l'acromion. La méthode présentée rend possible l'investigation de la pathogénie du défilé du m. supraépineuxin vivo avec une plus grande précision que ce qui a été possible jusqu'alors avec la radiographie conventionnelle.
    Notes: Summary A reduction of the subacromial space and an increased subacromial pressure have been considered to play an important role in the pathogenesis of rotator cuff lesions. The objective of the current study was to develop a CT based method for measuring the acromiohumeral distance and inferior acromial mineralization. In seven patients with unilateral rupture of the rotator cuff and two with impingement syndrome, transverse CT images were obtained at a section thickness of 1 mm with muscular relaxation in a standardized position. The bones were then reconstructed three-dimensionally, and the minimal vertical distance between the acromion and the humerus was determined in three secondary frontal images on both sides. The distribution of mineralization within the inferior surface of the acromion was assessed using CT osteoabsorptiometry. Although the Constant score was significantly reduced in the diseased shoulders, the width of the subacromial space was not routinely lower than on the contralateral side. In seven cases the maximal inferior acromial mineralization was identical in both shoulders, and in two cases it was lower on the affected side. These preliminary data suggest that with muscular relaxation no narrowing of the subacromial space can be detected in secondary frontal CT images, and that a potential increase of subacromial pressure is not high enough to cause a measurable increase in inferior acromial bone density. The method presented makes it possible to investigate the pathogenesis of the supraspinatus outlet syndromein vivo with greater precision than has so far been possible with conventional radiography.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1279-8517
    Keywords: Shoulder ; Supraspinatus outlet syndrome ; Computed tomography ; Mineralization ; Subacromial space
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A reduction of the subacromial space and an increased subacromial pressure have been considered to play an important role in the pathogenesis of rotator cuff lesions. The objective of the current study was to develop a CT based method for measuring the acromiohumeral distance and inferior acromial mineralization. In seven patients with unilateral rupture of the rotator cuff and two with impingement syndrome, transverse CT images were obtained at a section thickness of 1 mm with muscular relaxation in a standardized position. The bones were then reconstructed three-dimensionally, and the minimal vertical distance between the acromion and the humerus was determined in three secondary frontal images on both sides. The distribution of mineralization within the inferior surface of the acromion was assessed using CT osteoabsorptiometry. Although the Constant score was significantly reduced in the diseased shoulders, the width of the subacromial space was not routinely lower than on the contralateral side. In seven cases the maximal inferior acromial mineralization was identical in both shoulders, and in two cases it was lower on the affected side. These preliminary data suggest that with muscular relaxation no narrowing of the subacromial space can be detected in secondary frontal CT images, and that a potential increase of subacromial pressure is not high enough to cause a measurable increase in inferior acromial bone density. The method presented makes it possible to investigate the pathogenesis of the supraspinatus outlet syndrome in vivo with greater precision than has so far been possible with conventional radiography.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular evolution 39 (1994), S. 80-86 
    ISSN: 1432-1432
    Keywords: Heat-shock proteins ; HSP70 ; Stress-70 ; Phylogenetic trees ; Protein families ; NLS
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The eukaryotic cyto-/nucleoplasmatic 70-kDa heat-shock protein (HSP70) has homologues in the endoplasmic reticulum as well as in bacteria, mitochondria, and plastids. We selected a representative subset from the large number of sequenced stress-70 family members which covers all known branches of the protein family and calculated and manually improved an alignment. Here we present the consensus sequence of the aligned proteins and putative nuclear localization signals (NLS) in the eukaryotic HSP70 homologues. The phylogenetic relationships of the stress-70 group family members were estimated by use of different computation methods. We present a phylogenetic tree containing all known stress-70 subfamilies and demonstrate the usefulness of stress-70 protein sequences for the estimation of intertaxonic phylogeny.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular evolution 37 (1993), S. 204-210 
    ISSN: 1432-1432
    Keywords: HMG box ; DNA-binding proteins ; High-mobility-group (HMG) proteins ; Phylogenetic trees ; Nuclear targeting sequences
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract HMG boxes were initially identified as DNA-binding domains of the human RNA polymerase I (pol I) transcription factor hUBF and the animal high-mobility-group (HMG) protein family HMG1. Since then, numerous sequences of HMG-box-containing HMG proteins and other DNA-binding proteins from several species have become available. By sequence comparisons of a selected range of HMG boxes from these proteins and the construction of phylogenetic trees we show that the HMG box is highly conserved between DNA-binding proteins of organisms from all three eukaryotic kingdoms and that HMG boxes are linked by distinct evolutionary relationships. In addition, most HMG boxes display comparable hydropathy profiles and amino acid arrangements, which could serve as nuclear targeting sequences.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-0983
    Keywords: Pyrenomonas salina (Cryptophyceae) ; Plastid ; DNA-dependent RNA polymerase α subunit
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The nucleotide sequence of the gene coding for the plastid-encoded α subunit of DNA-dependent RNA polymerase from the cryptomonad alga Pyrenomonas salina was determined. The deduced amino-acid sequence, corresponding to a 35.2 kDa polypeptide, was compared to homologues from other organisms. Evolutionary relationships were analyzed in detail by the parsimony method together with bootstrap analysis. The deduced phylogenetic tree shows that the cryptomonad gene is the most ancient type of known plastid-encoded RNA polymerase.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Gene 150 (1994), S. 299-302 
    ISSN: 0378-1119
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 162 (1989), S. 456-463 
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Molecular Phylogenetics and Evolution 3 (1994), S. 187-191 
    ISSN: 1055-7903
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 68 (1997), S. 2800-2804 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A new ultrahigh vacuum instrument allowing in situ Kerr microscopy and scanning tunneling microscopy is described. The Kerr microscope has a spatial resolution of about 1 μm. First experimental results are reported on the magnetism of a 5 μm wide stripe consisting of six atomic layers of Fe grown in situ by molecular beam epitaxy on a W(110) surface. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 87 (2000), S. 5099-5101 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have measured the magnetization of in-plane magnetized ultrathin magnetic dots of Co on Cu(100) as a function of temperature and applied field by scanning Kerr microscopy. Co dots with lateral sizes down to 4 μm and a thickness of 1.8 atomic layers show a sharp magnetic phase transition which is indistinguishable from the one of extended films. The scaling plot suggests that these small particles belong to the Ising universality class. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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