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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Nuclear Instruments and Methods 112 (1973), S. 519-525 
    ISSN: 0029-554X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 20 (1941), S. 1054-1056 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung 1. Bei normalen mit Dial narkotisierten Hunden findet eine mit dem Zuckergehalt des Blutes wachsende Zuckerverbrennung statt. 2. Bei pankreasektomierten Hunden, und zwar bei narkotisierten wie bei wachen Tieren, steigt nach einer Glucoseeinspritzung der RQ. nur gering an. 3. Daraus geht hervor, daß pankreasektomierte Tiere nicht imstande sind, den Zucker zu verbrennen, wenn auch die Glykämie hohe Werte erreicht, und daß in jedem Falle der Glucoseverbrauch konstant bleibt, auch wenn sich der Zuckergehalt des Blutes in weiterem Maße ändert. 4. Diese Ergebnisse entsprechen den Schlußfolgerungen vonSoskin undLevine, welche sie erhielten, indem sie von Berechnungen ausgingen, welche auf andere Voraussetzungen aufgebaut, mit unseren Ergebnissen übereinstimmen würden. 5. Aus den Bestimmungen des täglich im Harn ausgeschiedenen Stickstoffs und Glucose beitn zuckerkranken und ohne Zucker gefütterten Hunde ergibt sich, daß die Glucoseproduktion im Organismus nicht höher als diejenige ist, die möglicherweise aus dem Eiweiß stammt. Es scheint deshalb nicht möglich, daß bei diesen Tieren eine Glucoseproduktion aus Fettsäuren stattfinden kann.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 22 (1934), S. 634-634 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 308 (1969), S. 197-202 
    ISSN: 1432-2013
    Keywords: Muscle Mechanical Efficiency ; O2 Debt Payment ; Phosphagen Concentration in Muscle ; Creatine Phosphate Speed and Efficiency of Resynthesis ; Muskel-Wirkungsgrad ; O2-Schuld-Ausgleich ; Phosphagen-Konzentration im Muskel ; Kreatinphospatresynthese-Geschwindigkeit und-Wirkungsgrad
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary From the amount of work at steady state, and the concentration of split phosphagen, equivalent to the oxygen debt, measured on an exercising isolated dog gastrocnemius, the velocity constant of phosphagen (ATP+CP) resynthesis, assuming that this reaction is an exponential one, could be calculated and found to be 1.98 min−1, the same value as found in man in exercise. The mechanical equivalent of phosphagen splitting in man has been calculated as 4.3 kcal/mol.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 326 (1971), S. 152-161 
    ISSN: 1432-2013
    Keywords: Exercise, Supramaximal ; Lactic Acid, Rate of Production ; Lactic Acid, Energy Equivalent of O2 Debt ; Muscular Exercise, Energy Sources in
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary On 12 subjects of different muscular fitness the rate of lactic acid appearance in blood, while performing the same supramaximal exercise has been determined, together with the maximal performance time and the maximal L.A. concentration in blood. The rate of increase of lactic acid is higher in the less fit than in the athletic subjects, to compensate for the lower oxygen consumption. In all subjects the appearance of L.A. in the blood is delayed: at the onset of the exercise other anaerobic processes (alactic) supply the energy required, and only when these are exhausted L.A. formation enters into play. The energy due to lactic acid corresponds to 37±3.5 ml of O2 per g of lactic acid increase in 1 l of blood, or 50 ml of O2 (or 250 cal) per g of L.A. produced from glycogen. The maximal amount of the lactacid debt is equivalent to about the maximum oxygen consumption in 1 min. A simple relation is found between the time of performance in supramaximal exercise and the maximum oxygen consumption.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 336 (1972), S. 225-235 
    ISSN: 1432-2013
    Keywords: Oxygen Breathing, Effect on Exercise ; Muscular Power, Maximal Aerobic ; Lactic Acid, Significance in Muscular Exercise
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Time of performance, blood lactic acid concentration (L.A.), heart rate (H.R.) and maximal oxygen consumption ( $$\dot V_{O_2 }^{\max } $$ ) were measured during air and oxygen breathin in 11 subjects performing a supramaximal exercise with an O2 requirement of 70 to 80 ml/kg·min to exhaustion. In addition the subjects were tested for maximal aerobic power with an indirect method. In one subject the rate of lactic acid increase in blood was also measured. The $$\dot V_{O_2 }^{\max } $$ measured with both the direct and the indirect method appears to be about 8% higher when breathing pure oxygen; lactic acid production rate decreases correspondingly. Maximal H.R. and maximal L.A. concentration were found to be the same. In submaximal exercise steady state H.R. is lower by about 8–9 beats/min when breathing oxygen. Also when breathing oxygen H.R. is a linear function of the work load. From experimental data obtained in subjects of different $$\dot V_{O_2 }^{\max } $$ , breathing both air or O2, the energy equivalent of L.A. could be calculated as amounting to about 47 ml of O2 or 235 cal per g of L.A. produced.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 304 (1968), S. 11-19 
    ISSN: 1432-2013
    Keywords: Oxygen Debt (Alactic) ; Phosphagen Resynthesis ; Sauerstoffschuld (“Alactacide”) ; Phosphagen-Resynthese
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The oxygen consumption together with lactic acid production and concentration of ATP, ADP, and creatinephosphate was measured during exercise and recovery on an isolated dog gastrocnemius. Oxygen debt contraction and payment follow an exponential path with a half reaction time of about 20 sec. The concentration of ATP and ADP at steady state seem to be unaffected by the intensity of the exercise when this is submaximal and no appreciable production of lactic acid takes place. The concentration of creatinephosphate in muscle at steady state decreases with the intensity of the exercise. The ratio of the oxygen consumption at steady state to the alactic oxygen debt is identified with the speed constant of the resynthesis of phosphagen in muscle; the half reaction time of this process is 17–20 sec. The total alactic oxygen debt amounts to about 50 ml/kg of muscle. These figures are in good agreement with earlier data found in man.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 9 (1936), S. 299-307 
    ISSN: 1439-6327
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Recovery processes have been studied in severe work of uniform intensity continuing from a minimum of 5 seconds to a maximum of 106 seconds. The work was largely anaerobic, requiring the accumulation of an oxygen debt, the magnitude of which was approximately a linear function of time. The rate of removal of lactic acid is a logarithmic function of time; the rate varies somewhat from time to time and from one person to another. In the type of activity studied the lactic acid accumulated is proportional to the duration of work. The total oxygen debt as well as the lactacid debt being proportional to duration of work, it follows that the so-called alactacid debt is also proportional to the duration of work. In other words, the lactacid debt and the alactacid debt in such activity are contracted concurrently. The oxygen intake in recovery may be analyzed into a rapid process nearly complete in 5 minutes which pays the alactacid debt, a process about 1/20th as rapid which pays the lactacid debt, and finally an increase in resting metabolism which decreases in a linear fashion until the pre-exercise level is reached. The excess R. Q for the entire process of work and recovery probably lies within the range 0,9 to 1,0.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 20 (1964), S. 281-287 
    ISSN: 1439-6327
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary On three trained subjects the effects of some drugs on a) the maximum oxygen consumption, b) the time of performance in an anaerobic exercise, c) the blood lactic acid, and finally d) the maximum heart rate, have been studied. The exercise was a run on a treadmill at 12 alternately 13.8 km/h on a 5% incline carried until exhaustion (ab. 5–6 mins). The drugs administered with a double blind system, were amphetamine (10 mg), caffeine (100 mg and resp. 250 mg), ascorbic acid (250 mg), flavon-7 — ethile ossiacetate (“Recordil”, 90 and 180 mg); the placebo was starch (250 mg). Five tests have been made for each drug and for each subject: the statistical analysis of the data shows that the drugs, as tested, have no significant effect on any of the tests made, including time of performance and maximum oxygen consumption, which seems to us particularly significant.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 29 (1971), S. 215-223 
    ISSN: 1439-6327
    Keywords: Exercise, supramaximal ; Lactic acid, rate of production ; Alkalosis, effect on exercise
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An increased base binding power of the blood induced by alkali administration to subjects performing a supramaximal exercise has no appreciable effect neither on the maximal performance time nor on the total amount of lactic acid or its rate of appearance in blood.
    Type of Medium: Electronic Resource
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