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  • 1
    Electronic Resource
    Electronic Resource
    MR imaging of hepatocellular carcinomas: effect of Cu and Fe contents on signal intensity (1997)
    Springer
    Abdominal imaging 22 (1997), S. 60 -66 
    Details
    ISSN: 1432-0509
    Keywords: Key words: Liver, neoplasms—Liver, metal—Magnetic resonance imaging—Hepatocellular carcinoma—Liver, signal intensity. [xm [fs99]
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Background: To elucidate the metallic factors contributing to the signal intensities of hepatocellular carcinoma (HCC) on T1-weighted magnetic resonance (MR) images and to determine whether or not changes in signal intensity contribute to the diagnosis of histological grading of HCC. Methods: In 35 patients immediately after surgery, the quantities of water, lipid, copper (Cu), iron (Fe), and manganese (Mn) were determined in HCCs and the surrounding hepatic parenchyma. The correlations among these findings, the histopathological findings, and the signal intensities of T1-weighted MR images were evaluated. Results: Among the 35 HCCs, 12 (34%) were of high intensity, 14 (40%) were isointense, and 9 (26%) were of low intensity on T1-weighted images versus the surrounding hepatic parenchyma. The paramagnetic ions, which contributed to the signal intensity patterns, were assumed to be Cu in HCCs (30.5 ± 52.9 μg/g ww), and Fe in the livers (106.2 ± 86.8 μg/g ww) and HCCs (87.7 ± 49.1 μg/g ww). In 12 HCCs with high intensity, one was grade I, eight were grade II, and three were grade III according to Edmondson-Steiner's histopathological classification. Conclusions: Signal intensity and signal intensity patterns alone cannot be signs of low-grade malignancy because of the Fe in livers and in HCCs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002619900141
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  • 2
    Electronic Resource
    Electronic Resource
    Bone Mineral Density in Patients Taking H2-Receptor Antagonist (1998)
    Springer
    Calcified tissue international 62 (1998), S. 283-285 
    Details
    ISSN: 1432-0827
    Keywords: Key words: Bone mineral density — Osteoporosis — H2-receptor antagonist — Dual energy X-ray absorptiometry — Gastrectomy.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. Osteoporosis after gastrectomy is a common clinical disorder. In gastrectomized patients, decreased gastric acidity may be associated with impaired calcium absorption. This study was undertaken to determine whether patients with chronic use of H2-receptor antagonists (HRA) had demonstrable decreases in bone mineral density (BMD). Thirty-three patients taking cimetidine, ranitidine, or famotidine for more than 2 years were analyzed. We measured BMD of L2–L4 using dual energy X-ray absorptiometry (DXA). Osteoporosis (BMD less than 0.70 g/cm2) was found only in three patients (9%). As compared with healthy controls, age- and sex-matched BMD ranged from 74.4% to 132.9%, with a mean of 97.0%, and was not influenced by the period of HRA use (〈5 years versus 〉5 years or more). Although the age- and sex-matched BMD was different among the kinds of HRA (98.6% for cimetidine, 101.3% for ranitidine, and 85.5% for famotidine), the relationship between the BMD and type of drug was not significant by multivariate analysis. These results indicate that chronic use of HRA has little influence on the degree of BMD, and suggest that decreased gastric acidity is not always associated with osteoporosis after gastrectomy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002239900431
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  • 3
    Electronic Resource
    Electronic Resource
    Osteoporosis After Gastrectomy: Bone Mineral Density of Lumbar Spine Assessed by Dual-Energy X-ray Absorptiometry (2000)
    Springer
    Calcified tissue international 66 (2000), S. 119-122 
    Details
    ISSN: 1432-0827
    Keywords: Key words: Osteoporosis — Gastrectomy — Dual-energy X-ray absorptiometry — Bone mineral density — Metabolic bone disease.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. Although osteoporosis is a common clinical disorder associated with gastric surgery, long-term effects of gastrectomy on bone metabolism are still unclear. The purpose of this study was to clarify the incidence and risk factors of osteoporosis after gastrectomy using univariate and multivariate analyses of quantitative measurements. The study included 59 patients who had undergone gastrectomy more than 5 years before. There were 38 men and 21 women, aged 37–81 years, mean 64 years. Bone mineral density (BMD) of L2–L4 spine was measured using dual-energy X-ray absorptiometry (DXA). Absolute value of BMD (g/cm2) and age- and sex-matched BMD (%) were given. The mean BMD was 0.766 g/cm2, and the incidence of osteoporosis (BMD less than 0.70 g/cm2) was 37%: 18% in men and 71% in women. The mean age- and sex-matched BMD was 85.9%: 87.5% in men and 83.1% in women. Univariate and multivariate analyses revealed that BMD was significantly associated with the age and sex of patients, but was not influenced by the type of gastrectomy (partial versus total) and years after operation (〈20 versus 20〈). Our study clarified the fact that postgastrectomy osteoporosis was frequent in the aged or female patients. BMD should be evaluated after gastrectomy, especially in the aged and in women.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002230010025
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  • 4
    Electronic Resource
    Electronic Resource
    Laparoscopy preferable to imaging procedures in detecting metastases of a pancreas carcinoma to the liver (1994)
    Springer
    Surgical endoscopy and other interventional techniques 8 (1994), S. 1340-1342 
    Details
    ISSN: 1432-2218
    Keywords: Laparoscopy ; Imaging procedures ; Pancreas carcinoma ; Hepatic metastases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In two patients a pancreatic mass, 6 and 4 cm in diameter, respectively, was detected using imaging techniques. Computed tomography, ultrasound, and angiography revealed no evidence of a metastatic lesion in the liver. In the first patient, exploration was done prior to a possible radical operation. Multiple hepatic metastases forming thin, flat lesions on the surface of the liver were present and palliative surgery only was done. In the other patient, laparoscopy was done before surgical exploration and multiple hepatic metastases on the surface of the liver were clearly evident. Laparoscopy can help to avoid unnecessary explorations in patients with large pancreas cancer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00188297
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  • 5
    Electronic Resource
    Electronic Resource
    Hepatic metastasis after laparoscopic cholecystectomy for polypoid gallbladder cancer followed by radical surgery (1994)
    Springer
    Surgical endoscopy and other interventional techniques 8 (1994), S. 1436-1438 
    Details
    ISSN: 1432-2218
    Keywords: Hepatic metastasis ; Polypoid gallbladder cancer ; Radical surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract While laparoscopic cholecystectomy is being increasingly performed on patients with gallbladder disease, this approach in cases of polypoid lesions in the gallbladder may not always be justified. We report here a case of early development of intrahepatic metastasis after laparoscopic cholecystectomy for polypoid gallbladder cancer; wedge resection of the gallbladder bed and dissection of regional lymph nodes had to be done. When a malignancy of the gallbladder is suspected during preoperative examinations, open cholecystectomy should be done.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00187354
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