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  • 1
    Electronic Resource
    Electronic Resource
    Impetigo herpetiformis with hyperparathyroidism (2005)
    Oxford, UK : Blackwell Science Ltd
    Journal of the European Academy of Dermatology and Venereology 19 (2005), S. 0 
    Details
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Impetigo herpetiformis, first described by Hebra, is a rare pustular disorder that primarily affects pregnant women and it is often complicated by an increased risk of spontaneous abortion. A commonly associated hypocalcemia often appears with hypoparathyroidism. Here we report a case of complicated impetigo herpetiformis without hypocalcemia paired with a compensatory hyperparathyroidism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1468-3083.2005.01293.x
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  • 2
    Electronic Resource
    Electronic Resource
    Congenital agminated segmental naevi (1995)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 133 (1995), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We report a 39-year-old woman with agminated segmental naevi on the right side of her face. The lesions were present at birth, and she had no other congenital abnormalities.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1995.tb02638.x
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  • 3
    Electronic Resource
    Electronic Resource
    Cowden's disease: clinical and molecular genetic findings in a patient with a novel PTEN germline mutation (2003)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 148 (2003), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary We report a 54-year-old woman with Cowden's disease (CD) who was found to carry a novel germline mutation in the PTEN gene. The mutation (c.334C→G) introduced a splice donor site within exon 5 that caused the expression of an aberrant transcript lacking 159 nucleotides corresponding to codons 112–164. Clinically, the patient showed multiple benign hamartomatous lesions of the skin, papillomatosis of the lips and oral mucosa, polyposis coli and bilateral fibrocystic disease of the breast. In addition, she developed different types of malignant neoplasms, including bilateral carcinomas of the breast and malignant melanomas of the skin. Molecular genetic analysis of a benign skin hamartoma and an invasive ductal breast carcinoma revealed loss of heterozygosity (LOH) at microsatellite markers on chromosome 10 in the carcinoma but not in the hamartoma. The breast carcinoma additionally carried a somatic TP53 point mutation (c.466C→G; R156G) that was associated with LOH on 17p and nuclear p53 protein accumulation. Taken together, our findings indicate that benign hamartomas in CD may develop without loss of the second (wild-type) PTEN allele, whereas the pathogenesis of malignant tumours, such as breast carcinomas, appears to require the complete inactivation of Pten as well as further alterations such as the loss of p53-dependent growth control.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.2003.05322.x
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  • 4
    Electronic Resource
    Electronic Resource
    Topical tacrolimus for oral cicatricial pemphigoid (2004)
    Oxford, UK : Blackwell Science Ltd
    Clinical and experimental dermatology 29 (2004), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2230.2004.01619.x
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  • 5
    Electronic Resource
    Electronic Resource
    Successful treatment of linear IgA disease with mycophenolate mofetil as a corticosteroid sparing agent (2005)
    Oxford, UK : Blackwell Science Ltd
    Clinical and experimental dermatology 30 (2005), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2230.2005.01741.x
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  • 6
    Electronic Resource
    Electronic Resource
    Discrete papular mucinosis—a rare subtype of lichen myxoedematosus (2000)
    Oxford, UK : Blackwell Science Ltd
    Clinical and experimental dermatology 25 (2000), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Lichen myxoedematosus is an uncommon and distinct disease entity characterized by cutaneous mucin deposition which, depending on the distribution and overall skin involvement, can be classified into several subtypes. We now describe the case of a discrete papular type of lichen myxoedematosus in a patient without any conspicious laboratory findings including normal thyroid function and the absence of any abnormal immunglobulins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2230.2000.00644.x
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  • 7
    Electronic Resource
    Electronic Resource
    Type 1 segmental cutaneous leiomyomatosis (2002)
    Oxford, UK : Blackwell Science Ltd
    Clinical and experimental dermatology 27 (2002), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary Cutaneous leiomyomas are rare benign tumours of the skin, which present in multiple disseminated, segmental or solitary forms. The pathogenesis of segmental cutaneous leiomyomatosis is not yet fully known. Most recently two types of segmental manifestation of autosomal dominant inherited diseases were postulated. Type 1 reflects heterozygosity for the underlying mutation with a clinical picture similar to that in a non-mosaic phenotype. In type 2, loss of heterozygosity leads to homo- or hemizygosity with a pronounced segmental manifestation of lesions in the affected segment. In our patient the lesions were restricted to one segment and therefore she most probably has a type 1 segmental cutaneous leiomyomatosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2230.2002.01089.x
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  • 8
    Electronic Resource
    Electronic Resource
    Toxic epidermal necrolysis in a premature infant of 27 weeks' gestational age (2005)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 152 (2005), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Toxic epidermal necrolysis (TEN) is very rare in the newborn period. So far, three cases of TEN in newborns have been reported worldwide. We report a premature infant of 27 weeks' gestational age with TEN at 4 weeks of age. Sepsis treated by an antibiotic combination regimen preceding the TEN was a common feature of all four cases. In our patient, coagulase-negative staphylococci could be identified by blood culture, whereas the previously reported patients suffered from Klebsiella pneumoniae sepsis or Escherichia coli sepsis. Possibly, the uniform association with septic infection in the cases of TEN in the neonatal period might hint at a causal association, thus differentiating it from TEN in older children or adults.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.2004.06258.x
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  • 9
    Electronic Resource
    Electronic Resource
    PREDICTION OF BENDING FATIGUE BEHAVIOUR BY THE REFERENCE STRESS APPROACH (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Fatigue & fracture of engineering materials & structures 13 (1990), S. 0 
    Details
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract— A technique is presented for prediction of low-cycle fatigue behaviour under bending conditions from the knowledge of uniaxial fatigue data. The technique utilizes the reference stress approach used in the analysis of creeping components. The results enable determination of nominal elastic bending stress in terms of the observed saturation stress amplitude in an uniaxial fatigue test conducted at a reference value of strain amplitude. The reference parameters are determined for beams with both rectangular and circular cross-sections. The predictions of fatigue bending behaviour are in excellent agreement with closed form solutions reported recently. The merits of this alternative approach lie in its potential applicability to other structural situations once their reference uniaxial parameters are determined. Since the reference parameters are nearly the same for both creep and fatigue, the approach can be a useful experimental tool for relating creep-fatigue interaction effects in structural components with uniaxial creep-fatigue tests conducted under the reference conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-2695.1990.tb00607.x
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  • 10
    Electronic Resource
    Electronic Resource
    Prästernales verruköses Karzinom (2000)
    Springer
    Der Hautarzt 51 (2000), S. 766-769 
    Details
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Verruköses Karzinom ; Ackerman-Tumor ; Buschke-Löwenstein-Tumor ; Epithelioma cuniculatum ; Keywords Verrucous carcinoma ; Ackerman's tumor ; Buschke-Löwenstein tumor ; Epithelioma cuniculatum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract Verrucous carcinomas represent rare, highly differentiated variants of squamous cell carcinoma. They preferentially develop on the oropharyngeal mucosa (Ackerman tumor), the urogenital mucosa (Buschke-Loewenstein tumors), and the soles of the feet (epitheliomata cuniculata). Various synonyma have been coined for these tumors. We report the uncommon occurrence of a large verrucous carcinoma on apparently uninvolved chest skin of a 79-year old patient. The tumor was excised radically. Complete extirpation was confirmed histologically and there was no sign of recurrence during a 3 month observation period. The clinical appearance, histomorphological features, epidemiological aspects, differential diagnosis, therapy, and nomenclature of verrucous carcinomas are discussed.
    Notes: Zusammenfassung Verruköse Karzinome repräsentieren seltene Sonderformen hochdifferenzierter Plattenepithelkarzinome. Sie treten bevorzugt an der oropharyngealen Mukosa (Ackerman-Tumoren), der urogenitalen Mukosa (Buschke-Löwenstein-Tumoren) und den Fußsohlen (Epitheliomata cuniculata) auf. Verschiedene Synonyme sind gebräuchlich für verruköse Karzinome unterschiedlicher Lokalisation. Wir berichten über das ungewöhnliche Auftreten eines großen verrukösen Karzinoms auf primär unbefallener Brusthaut bei einem 79-jährigen Patienten. Der Tumor wurde, histologisch kontrolliert, vollständig exzidiert, und in der bis jetzt 3-monatigen Nachbeobachtungsphase fand sich kein Anhalt für ein Rezidiv. Anhand dieses Falls werden klinische Erscheinungsformen, histomorphologische Charakteristika, epidemiologische Aspekte, Differenzialdiagnose, Therapie und Nomenklatur verruköser Karzinome diskutiert.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001050051212
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