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  • 1
    Electronic Resource
    Electronic Resource
    Anomaly of venous system in congenital occipital dermal sinus (1994)
    Springer
    Acta neurochirurgica 128 (1994), S. 174-179 
    Details
    ISSN: 0942-0940
    Keywords: Congenital occipital dermal sinus ; dural sinuses ; development ; embryology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We report two cases of congenital occipital dermal sinus in which elongation of the vein of Galen, elevation of the straight sinus, division of the superior sagittal sinus, elevation of the confluence of sinuses, elevation of transverse sinus and narrowing of the torcular angle were observed in the venous phase of cerebral angiography. Enhanced computed tomography (CT) revealed enlargement of the supracerebellar cistern, elevation of the straight sinus and of the confluence of sinuses, but no evidence of intracranial lesions. In order to study the relationship between anomalies in the dural venous sinuses and congenital occipital dermal sinus, we examined both cases from an embryological viewpoint.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01400671
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  • 2
    Electronic Resource
    Electronic Resource
    Stump pressure as a guide to the safety of permanent occlusion of the internal carotid artery (1996)
    Springer
    Acta neurochirurgica 138 (1996), S. 549-554 
    Details
    ISSN: 0942-0940
    Keywords: Balloon test occlusion ; stump pressure ; back pressure ; 99 mTc-HMPAO SPECT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Does the absolute value of the stump pressure (post-occlusion back pressure) become a useful index of a good collateral circulation? The authors continuously monitored the mean arterial pressure before, during and after 20-minute balloon test occlusion in 24 patients. The stump pressure was then compared with the results of99 mTc-hexa-methyl propyleneamine (99 mTc-HMPAO) single photon emission computed tomography (SPECT) performed after 20 minutes of test occlusion. Patients who failed to tolerate even brief periods of carotid occlusion and showed asymmetric decreases in cerebral blood flow (CBF) on SPECT were divided into high and moderate risk groups. Those with no significant change in CBF on the occluded side formed the minimum risk group. Mean stump pressure was over 50 mmHg in three of a total of 13 patients in the high and moderate risk groups, and below 50 mmHg in two of the 11 patients in the minimum risk group. The ratios of the initial mean stump pressure to the pre-occlusion mean arterial pressure (%) and of the final mean stump pressure at the end of occlusion to the post-opening mean arterial pressure (%) did not exceed 58% in any patient in the high and moderate risk groups, and were at least 60% in all patients of the minimum risk group. Maintenance of a mean stump pressure of 60% or more of the mean systemic pressure during test occlusion may be a more useful index of a good collateral circulation than the absolute value of mean stump pressure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01411175
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  • 3
    Electronic Resource
    Electronic Resource
    The Influence of Vascular Pressure and Angiographic Characteristics on Haemorrhage from Arteriovenous Malformations (2000)
    Springer
    Acta neurochirurgica 142 (2000), S. 39-43 
    Details
    ISSN: 0942-0940
    Keywords: Keywords: Arteriovenous malformation; haemorrhage; vascular pressure.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary ¶ Background. The present study was designed to determine whether there is a physiological explanation for the predisposition of patients with certain angiographic characteristics to haemorrhage from cerebral arteriovenous malformations (AVMs).  Methods. Intra-operative measurement of feeding artery pressure (FAP) and intravascular pressures in the draining venous system [draining vein pressure (DVP) and cranial sinus pressure (SP)] were performed for 30 AVM cases using direct puncture of the vessels. The correlation between pressures and previously described angiographic characteristics predisposing to haemorrhage were evaluated.  Findings. Small nidus size and only one draining vein increased the risk of haemorrhage. FAP and DVP are both inversely related to the number of draining veins and the size of the AVMs. DVP was significantly higher in AVMs with haemorrhage (23.1±8.7 mmHg) than in those without (13.5±4.4), as was FAP (58.6±12.8 as opposed to 38.7±4.7) (p〈0.05). Moreover, the difference between systemic blood pressure and the FAP with haemorrhagic AVMs (17.0±9.5 mmHg) was significantly lower than that in nonhaemorrhagic cases (33.7±5.5) (p〈0.05). The pressure difference between the feeding artery and draining vein was not significant between the haemorrhagic and nonhaemorrhagic groups. There was no significant difference of SP between haemorrhagic and nonhaemorrhagic patients.  Interpretation. The present study suggests that a high DVP probably induced by high resistance in the venous drainage system, as well as a high FAP, may contribute to the development of haemorrhage from AVMs, and physiologically supports previous reports that small AVMs and AVMs with only one draining vein are susceptible to haemorrhage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007010050005
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  • 4
    Electronic Resource
    Electronic Resource
    The Factors Influencing Haematoma Volume due to Arteriovenous Malformations (1999)
    Springer
    Acta neurochirurgica 141 (1999), S. 385-388 
    Details
    ISSN: 0942-0940
    Keywords: Keywords: Arteriovenous malformation; cerebral haemorrhage; haematoma volume; angiography; computed tomography.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary  Haemorrhage due to cerebral arteriovenous malformations (AVMs) varies from massive, requiring urgent operations, to clinically silent. The present study was designated to identify factors influencing haematoma size, and the pathophysiological mechanisms of massive haemorrhage were studied. 55 patients with intracerebral haematomas due to supratentorial AVMs were included in this study. Angiographic and clinical findings were retrospectively evaluated in relation to haematoma size.  Statistical analysis demonstrated that small size and the presence of only one draining vein were high risk factors for massive haemorrhage. The haematoma volume in small AVMs (30±4 cm3) was significantly larger than in other AVMs (7±3 cm3) (p=0.0005). AVMs with only one draining vein were associated with massive haematoma volume as compared to AVMs with two or more draining veins (30±4 versus 11±3 cm3, p=0.0023).  Our previous study demonstrated that feeding artery pressure (FAP) was significantly higher in AVMs with haemorrhage than in those without, as was draining vein pressure (DVP), and FAP and DVP were inversely related to the number of draining veins and the size of the AVMs. Thus, in small AVMs and AVMs with only one draining vein, local increase in DVP may thus contribute to massive haemorrhage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007010050314
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  • 5
    Electronic Resource
    Electronic Resource
    A source of haemorrhage in adult patients with moyamoya disease: The significance of tributaries from the choroidal artery (1996)
    Springer
    Acta neurochirurgica 138 (1996), S. 1282-1286 
    Details
    ISSN: 0942-0940
    Keywords: Moyamoya disease ; intraventricular haemorrhage ; angiography ; choroidal artery ; medullary artery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This study concerns 19 patients over 16 years of age with Moyamoya disease. Ten cases of intracranial haemorrhage, as the initial haemorrhagic event in patients aged from 21 to 55 (haemorrhagic group) and 9 cases of ischaemic events in 18- to 53-year-old patients (ischaemic group) were included. All haemorrhages were associated with intraventricular haemorrhages (IVH); and all but one case of thalamic haemorrhage were thought to be primary IVH (2 cases of small paraventricular haemorrhage; 2 of small haemorrhages in the splenium; 5 with no intracerebral haematoma). In the 9 patients of the ischaemic group, there were 2 cases of transient ischaemic attacks and 7 of cerebral infarction. Angiographic evaluations demonstrated that the abnormal basal vessel formation and the collateral supplies from the external carotid arteries were poorly developed in both groups. In contrast, the collateral circulation via the choroidal and posterior pericallosal arteries was well demonstrated. Furthermore, marked enlargement of the choroidal arteries and the medullary arteries derived from them was seen more frequently in the haemorrhagic group. These findings suggested that the haemodynamic load in the vessels supplying the walls of the posterior parts of the ventricles and the periventricular region was increased, especially in the haemorrhagic group. Those vessels were considered to be important sites of IVH in adult patients with Moyamoya disase.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01411056
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  • 6
    Electronic Resource
    Electronic Resource
    The Value of Long-Term Clinical Follow-up for Cases of Spontaneous Carotid Cavernous Fistula (1998)
    Springer
    Acta neurochirurgica 140 (1998), S. 65-72 
    Details
    ISSN: 0942-0940
    Keywords: Keywords: Spontaneous CFF; long-term follow-up; transarterial embolization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To clarify the value of clinical long-term follow-up with radiological examination, ranging from 12 to 63 months (average: 35 months), 18 consecutive patients suffering from spontaneous carotid cavernous fistula (CCF), were studied prospectively. Five aged patients without aggressive symptoms were treated conservatively, and the other 13 underwent transarterial embolization. The radiological follow-up was primarily by magnetic resonance angiography (MRA), performed from 2 to 6 times (average: 4.1 times) during the follow-up period. In three cases, CCFs persisted, but the other fifteen (83%) demonstrated complete cure as defined by long-term follow-up MRA. The three patients with persistent CCFs were comparatively young, less than 60 years old, had no atherosclerotic factors and demonstrated multiple venous drainage routes with cortical venous drainage on angiography. In two of them, the symptoms completely disappeared, and the other had only mild chemosis. However, surprisingly, in two, MRA revealed residual CCF with drainage into only cortical veins through the sphenoparietal sinus, this radiological finding being well known to signify danger. During the follow-up period, central retinal vein thrombosis occurred in two cases. The common point in these cases was that the superior ophthalmic vein was the only venous drainage route. This is also a point requiring care. We therefore emphasize the importance of careful long-term radiological follow-up for spontaneous CCF patients even when their symptoms improve or disappear. MRA is particularly suitable for this purpose and applicable in the out-patient clinic because of its non-invasive nature.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007010050059
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  • 7
    Electronic Resource
    Electronic Resource
    Effect of semi-random mutagenesis at the C-terminal 4 amino acids of human interleukin-6 on its biological activity
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 187 (1992), S. 18-25 
    Details
    ISSN: 0006-291X
    Keywords: [abr] ORF; open reading frame ; [abr] PCR; polymerase chain reaction ; [abr] RP; reversed phase ; [abr] WT; wild type ; [abr] hIL; recombinant human interleukin
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/S0006-291X(05)81452-4
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  • 8
    Electronic Resource
    Electronic Resource
    Continuous perfusion with interleukin 6 (IL-6) enhances production of hematopoietic stem cells (CFU-S)
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 159 (1989), S. 933-938 
    Details
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0006-291X(89)92198-0
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  • 9
    Electronic Resource
    Electronic Resource
    Effect of semi-random mutagenesis at the C-terminal 4 amino acids of human interleukin-6 on its biological activity
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 187 (1992), S. 18-25 
    Details
    ISSN: 0006-291X
    Keywords: [abr] ORF; open reading frame ; [abr] PCR; polymerase chain reaction ; [abr] RP; reversed phase ; [abr] WT; wild type ; [abr] hIL; recombinant human interleukin
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/S0006-291X(05)81452-4
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Low-temperature annealing effect of as-grown Bi-Sr-Ca-Cu-O thin films on superconducting property and the c-axis lattice constant (1989)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 55 (1989), S. 1360-1362 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: As-grown crystallized Bi2Sr2Ca1Cu2Ox phase films were prepared on MgO(100) substrates by rf magnetron sputtering. The as-grown film showed the Tc onset of 92 K and the Tc end of 82 K. By annealing in the furnace at 480 °C after deposition, superconducting property and the c-axis lattice constant varied with atmosphere during annealing. The film after annealing in air at 480 °C exhibited the highest superconducting transition with the Tc onset of 93 K and the Tc end of 85 K. The Tc onset increased when the c-axis lattice constant was increased, suggesting that the Tc onset increases with decreasing the oxygen content of the film.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.101897
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