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  • 1
    Electronic Resource
    Electronic Resource
    Cryogenic Transmission Electron Microscopic Studies of Micellar Structure Correlated with Solution Viscosity on Perfluorooctyl Sufonates and Their Mixtures with a Nonionic Surfactant (1995)
    s.l. : American Chemical Society
    Langmuir 11 (1995), S. 2361-2366 
    Details
    ISSN: 1520-5827
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/la00007a008
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  • 2
    Electronic Resource
    Electronic Resource
    Protein C activation in NIDDM patients (1996)
    Springer
    Diabetologia 39 (1996), S. 1455-1461 
    Details
    ISSN: 1432-0428
    Keywords: Keywords Protein C ; protein S ; diabetes mellitus ; soluble thrombomodulin ; microalbuminuria ; activated protein C-protein C inhibitor complex ; fibrin monomer ; soluble E-selectin.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Enhanced activation of the clotting system has been recently implicated in the pathogenesis of vascular complications in patients with diabetes mellitus. Abnormalities of the anticoagulant system may constitute a potential trigger factor for the haemostatic activation observed in diabetic subjects. The current study aimed to evaluate anticoagulant activity in diabetic patients by assessing the plasma levels of activated protein C-protein C inhibitor complex; and by measuring the anticoagulant response to exogenous thrombomodulin. This study comprised 61 patients (34 men, 27 women) with non-insulin-dependent diabetes mellitus (NIDDM) of whom 22 showed microalbuminuria and 39 normoalbuminuria. Data obtained in 31 non-obese and non-diabetic subjects were available for comparison. The plasma levels of fibrinogen (p 〈 0.02), prothrombin fragment 1 + 2 (p 〈 0.05), fibrin monomer (p 〈 0.0001), protein C antigen (p 〈 0.005), total protein S antigen (p 〈 0.02), soluble thrombomodulin (p 〈 0.005) and soluble E-selectin (p 〈 0.005) were significantly higher in diabetic patients than in healthy subjects. The plasma level of activated protein C-protein C inhibitor complex (7.4 ± 3.8 vs 3.0 ± 0.4 pmol/l) was significantly higher (p 〈 0.0001) and the anticoagulant response to exogenous thrombomodulin (23.4 ± 2.6 vs 35.3 ± 3.0 ng/ml) was markedly lower (p = 0.005) in all diabetic patients than in healthy subjects. Cases with microalbuminuria presented low plasma levels of activated protein C-protein C inhibitor complex (5.5 ± 0.6 vs 8.6 ± 0.7 pmol/l, p 〈 0.05) and significantly decreased values of the anticoagulant response to exogenous thrombomodulin (16.5 ± 2.9 vs 23.4 ± 2.6 %, p = 0.03) as compared to those with normoalbuminuria. The present study suggests that the hyper-coagulable state in NIDDM is associated with an increased activation of protein C but with a poor plasma reactivity to the anticoagulant effect of thrombomodulin. [Diabetologia (1996) 39: 1455–1461]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001250050598
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  • 3
    Electronic Resource
    Electronic Resource
    Urinary acidic glycosaminoglycans in Werner's syndrome (1982)
    Springer
    Cellular and molecular life sciences 38 (1982), S. 313-314 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The composition of urinary acidic glycosaminoglycans (AGAG) in 4 patients with Werner's syndrome was determined by an enzymatic assay system using chondroitinases and hyaluronidase. In Werner's syndrome, the amount of hyaluronic acid and heparan sulfates in the total AGAG increases. A compositional change in the chondroitin sulfate isomers occurs. The change of urinary AGAG in Werner's syndrome appears to reflect age-related changes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01949362
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  • 4
    Electronic Resource
    Electronic Resource
    Einfluß des Klimas auf den experimentellen Hochdruck in Kaninchen (1969)
    Springer
    Journal of molecular medicine 47 (1969), S. 927-928 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Unilateral renal artery constriction was performed in 14 rabbits during the warm season and in 11 rabbits during the cold season. The rise of blood pressure after the renal artery constriction was greater in the latter than in the former group.
    Notes: Zusammenfassung Einseitige Nierenarteriendrosselung wurde bei 14 Kaninchen in der warmen Jahreszeit und bei 11 Kaninchen in der kalten Jahreszeit durchgeführt. Der durch Nierenarteriendrosselung ausgelöste Blutdruckanstieg war größer in der letzteren als in der ersteren Gruppe.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01486272
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  • 5
    Electronic Resource
    Electronic Resource
    Asymptomatic sequelae to acute sarin poisoning in the central and autonomic nervous system 6 months after the Tokyo subway attack (1997)
    Springer
    Journal of neurology 244 (1997), S. 601-606 
    Details
    ISSN: 1432-1459
    Keywords: Key words Sarin poisoning ; Asymptomatic sequelae ; Neurotoxicity ; Neurophysiological methods ; Posttraumatic stress ; disorder
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Six to eight months after the Tokyo subway attack in March 1995, the neurophysiological effects of acute sarin poisoning were investigated in 18 passengers exposed to sarin (sarin cases) in the subways to ascertain the focal or functional brain deficits induced by sarin. The event-related and visual evoked potentials (P300 and VEP), brainstem auditory evoked potential, and electrocardiographic R-R interval variability (CVRR), together with the score on the posttraumatic stress disorder (PTSD) checklist, were measured in the sarin cases and the same number of control subjects matched for sex and age. None of the sarin cases had any obvious clinical abnormalities at the time of testing. The P300 and VEP (P100) latencies in the sarin cases were significantly prolonged compared with the matched controls. In the sarin cases, the CVRR was significantly related to serum cholinesterase (ChE) levels determined immediately after exposure; the PTSD score was not significantly associated with any neurophysiological data despite the high PTSD score in the sarin cases. These findings suggest that asymptomatic sequelae to sarin exposure, rather than PTSD, persist in the higher and visual nervous systems beyond the turnover period of ChE; sarin may have neurotoxic actions in addition to the inhibitory action on brain ChE.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004150050153
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  • 6
    Electronic Resource
    Electronic Resource
    Continuous production of glucose-6-phosphate by immobilized Achromobacter butyri cells (1979)
    Springer
    Applied microbiology and biotechnology 7 (1979), S. 45-51 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Whole cells of Achromobacter butyri OUT 8004 having polyphosphate glucokinase activity were immobilized in polyacrylamide gel. The immobilized cells were activated by organic solvents, especially acetone. The immobilization resulted in increased stability of polyphosphate glucokinase. Continuous high yield production of G-6-P from glucose and metaphosphate was performed with an immobilized cell column, which had a half-life of approximately 20 days.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00522477
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  • 7
    Electronic Resource
    Electronic Resource
    Continuous production of glutathione by immobilized Saccharomyces cerevisiae cells (1978)
    Springer
    Applied microbiology and biotechnology 6 (1978), S. 23-27 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Glutathione was continuously produced by an immobilized Saccharomyces cerevisiae IFO 2044 cell column. The production of glutathione was strongly influenced by the level of activity of the glycolytic pathway. This activity was maintained constant by the addition of NAD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00500853
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  • 8
    Electronic Resource
    Electronic Resource
    Facet formation sign in sarcoidosis: a new sign in endoscopic ultrasonography (1992)
    Springer
    European radiology 2 (1992), S. 526-531 
    Details
    ISSN: 1432-1084
    Keywords: Endoscopy ; Lymphatic system, ultrasound studies ; Lymphatic system, diseases ; Mediastinum, ultrasound studies ; Sarcoidosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Endoscopic ultrasound was performed in 56 patients with histologically or clinically proven mediastinal or lung diseases. These 56 patients comprised 12 with sarcoidosis, 8 with lymphoma, 20 with lung cancer, 10 with oesophageal cancer, and 6 with other diseases. A 7.5 MHz electronic linear-arrayed ultrasonic endoscope was used. In 38 of the 56 patients lymph nodes were detected by endoscopic ultrasound. Eleven patients with sarcoidosis showed lymph nodes in a “facet formation” (like stones in an old stone wall), while lymph nodes in the other 27 patients were round in shape and did not form facets. The “facet formation sign”, evaluated by endoscopic ultrasound, may be a characteristic finding in sarcoidosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00187546
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  • 9
    Electronic Resource
    Electronic Resource
    Effects of glutamate and GABA on specific response properties of neurones in the visual cortex (1974)
    Springer
    Experimental brain research 21 (1974), S. 285-297 
    Details
    ISSN: 1432-1106
    Keywords: Visual cortex ; Receptive fields ; Response specificity ; Electrophoresis ; Glutamate ; GABA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Changes of specific response properties of single neurones in area 17 of the cat's cortex were studied during electrophoretic administration of glutamate and gamma-aminobutyric acid (GABA). Most cells were excited by glutamate. The diameter of the cells' discharge field (ERF) was enlarged by less than 1° in most cells, and the amplitude of the response within the ERF was increased. There was a weak correlation between the original size of the ERF and its enlargement during glutamate. Stimuli presented in non-optimal orientations and moved in the non-optimal direction became also effective in eliciting an excitatory response. When glutamate “doses” sufficiently high to increase background activity were used, inhibitory regions of the receptive fields could be revealed. GABA decreased the excitability of the cells until the response was totally blocked. In some cases, glutamate also decreased the excitability of cells. Simultaneous recordings from two cells suggested that the inhibitory effect may be indirect through activation of nearby inhibitory neurones. It is pointed out that extracellular recording combined with electrophoretic administration of glutamate can reveal information about a cell's properties which can otherwise only be obtained with intracellular recordings. The functional implications of the results are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00235748
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  • 10
    Electronic Resource
    Electronic Resource
    Development of New Container Manufacturing Process by Vertical Type Centrifugal Casting Method and its Solidification Analysis (1997)
    s.l. ; Stafa-Zurich, Switzerland
    Advanced materials research Vol. 4-5 (Oct. 1997), p. 307-312 
    Details
    ISSN: 1662-8985
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/40/transtech_doi~10.4028%252Fwww.scientific.net%252FAMR.4-5.307.pdf
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