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  • 1
    Electronic Resource
    Electronic Resource
    Tadpole Collagenase. Preparation and Purification* (1966)
    s.l. : American Chemical Society
    Biochemistry 5 (1966), S. 3123-3130 
    Details
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bi00874a007
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  • 2
    Electronic Resource
    Electronic Resource
    Low-molecular-weight enzyme inhibitors suppress the development of experimental allergic encephalomyelitis (1984)
    Springer
    Cellular and molecular life sciences 40 (1984), S. 1405-1407 
    Details
    ISSN: 1420-9071
    Keywords: Enzyme inhibitors ; experimental allergic encephalomyelitis ; cell surface enzymes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary We tested the activity of low-molecular-weight enzyme inhibitors with immunomodifying actions on the suppression of experimental allergic encephalomyelitis (EAE). Of the agents tested the inhibitors of alkaline phosphatase, aminopeptidase B and esterase gave significant protection againts the clinical expression of EAE in guinea pigs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01951914
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  • 3
    Electronic Resource
    Electronic Resource
    Culture experiments on the sea urchin Strongylocentrotus pulcherrimus fed an artificial diet (1975)
    Springer
    Marine biology 29 (1975), S. 105-108 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The omnivorous sea urchin Strongylocentrotus pulcherrimus inhabits the coast of Japan. It also ingests foreign foods, which are not normally present in the natural habitat. In cultures, foreign foods, such as white fish meal, shellfish meal, milk casein, gelatin, soybean meal, yellow corn, alfalfa and yeast were provided in the form of a moist and soft material and their ingestion and digestibility were examined. The foreign foods were prepared by mixing with agar-agar. Digestibility of the diet, and that of nitrogen contained in the diet, was estimated as 54.7 and 64.7% dry weight. Sea urchins cultivated over a period of 5 months on such a foreign diet exhibited 24% increase in wet weight during this period. Occasionally, the ingestion of artificial food suddenly decreased, but was soon resumed upon supplying a hot-water extract of brown algae.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00388981
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  • 4
    Electronic Resource
    Electronic Resource
    Feeding factors for the sea anemone Anthopleura midorii (1973)
    Springer
    Marine biology 18 (1973), S. 55-60 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The carnivorous feeding behavior of the sea anemone Anthopleura midorii was found to be a sequence of successive feeding motions, which consisted of several separate actions: (1) tentaculation on any solid matter; (2) retention of prey by tentacles; (3) mouth opening; (4) ingestion of food; (5) digestion of food; (6) extrusion of indigestible waste material. Hot water extract of a natural prey induced the entire feeding sequence when extract was given in the form of an artificial food by mixing with α-potato starch and water. The fractionated extract induced only a limited feeding action. Several amino acids induced feeding. Alanine, glycine or histidine stimulated the retention of artificial food by tentacles, and proline evoked mouth opening. Cysteine or reduced glutathione (GSH) induced food ingestion. Unnatural food stuff such as α-potato starch was ingestible, if an appropriate amount of a chemical substance was added.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00347921
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  • 5
    Electronic Resource
    Electronic Resource
    Evaluation of the antiviral effect of synthetic oligopeptides whose sequences are derived from paramyxovirus F1 N termini (1990)
    Springer
    Medical microbiology and immunology 179 (1990), S. 87-94 
    Details
    ISSN: 1432-1831
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We examined the antiviral effects of three oligopeptides, carbobenzoxy (Z)-d-Phe-Ile-Gly, Z-d-Leu-Ile-Gly and Z-d-Phe-Phe-Gly, which mimic the N-terminal regions of F1 glycoproteins of two Newcastle disease virus strains (Miyadera and D26) and Sendai virus, respectively. Only one of these peptides, Z-d-Phe-Phe-Gly, significantly and with a similar potency inhibited viruses of homologous and heterologous F1 N-terminal sequences, suggesting no strict sequence requirement for inhibition. Furthermore, the enveloped RNA viruses of several different families showed essentially the same sensitivity to the three peptides as the paramyxoviruses, while a nonenveloped RNA virus was not susceptible to any of them. In addition, the Z-d-Phe-Phe-Gly peptides was effective only when the virus particles had been pretreated before infection.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00198529
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  • 6
    Electronic Resource
    Electronic Resource
    Studies on the adaptation of mumps virus to chick embryo (1986)
    Springer
    Medical microbiology and immunology 174 (1986), S. 295-304 
    Details
    ISSN: 1432-1831
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract About 15 serial passages of wild type mumps virus (Sasazaki strain) in the amnion sac of chick embryo (CE) yielded a CE-adapted strain which was poorly replicative and did not form plaques in Vero cells where the wild strain grew well. In the course of this limited replication of the CE-adapted strain in Vero cells, we have analysed the viral protein and RNA synthesis. It was found that protein synthesis took place very efficiently at least early in infection by 12 h. The subsequent rate of synthesis remained, however, at a low level without showing the progressively increasing synthesis observed with the wild strain. Furthermore, 50S genomic RNA was synthesized early in the limited infection, but the subsequent synthesis was markedly suppressed. In addition, the other virus-specific RNA species could not be detected throughout. Thus the amplified RNA synthesis observed in the permissive CE cells and in the wild strain-infection of Vero cells seemed not to occur in the limited replication. Neither interferon nor DI (defective interfering) RNA was involved in the limited virus growth. When Vero cells were infected with the wild strain 6 to 8 h before inoculation of CE-adapted strain, growth restriction was overcome and the yield of the latter virus was greatly enhanced by a factor more than 103. These results suggest that through adaptation to CE, mumps virus may be altered in such a way that there is a restriction, probably at a step (s) involved in amplification of the viral RNA synthesis in Vero cells and that the restriction may be overcome by the simultaneous genome expression of the prototype wild strain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02123682
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  • 7
    Electronic Resource
    Electronic Resource
    Protein kinase associated with Newcastle disease virus (1984)
    Springer
    Medical microbiology and immunology 172 (1984), S. 223-231 
    Details
    ISSN: 1432-1831
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Purified virions of Newcastle disease virus (NDV) were found to contain protein kinase activity which was, like other virion-associated kinases, stimulated by Mg2+ and totally independent of Ca2+ and cAMP. The kinase phosphorylated preferentially the P and NP polypeptides of NDV. Triton-KCl fractionation of the virions has shown that the protein kinase activity may be associated with glycoprotein-free subviral particles, but not with nucleocapsids containing either only NP or some L and P proteins together with NP as protein constituent.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02123717
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  • 8
    Electronic Resource
    Electronic Resource
    Inhibition of lymphocyte DNA synthesis by plasma from patients with Kawasaki disease (1986)
    Springer
    European journal of pediatrics 145 (1986), S. 517-521 
    Details
    ISSN: 1432-1076
    Keywords: Immunosuppressive factor ; Kawasaki disease ; Lymphocyte DNA synthesis ; Patient's plasma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Plasma obtained from patients with Kawasaki disease during the acute phase markedly inhibited DNA synthesis in autologous peripheral blood lymphocytes (PBLs) stimulated by phytohaemagglutinin-P (PHA-P) or concanavalin A (Con A). The inhibition became less marked with the progression of the disease and there was no effect on DNA synthesis in PBLs stimulated by pokeweed mitogen (PWM). The plasma also inhibited DNA synthesis in PBLs obtained from healthy adults. The postulated suppressors markedly inhibited DNA synthesis in PBLs from healthy adults stimulated by PHA-P, Con A, purified protein derivative (PPD) or mixed lymphocyte culture reaction (MLR) but they had little effect on the DNA synthesis stimulated by PWM or protein A. With respect to the mechanism, the suppression was found to be potentiated by an increase in the concentration of the patients' plasma, and not to be associated with cytotoxicity nor with a deficiency of factor(s) indispensable for PBL proliferation. It was also evident that the suppression was not related to the concentration of the stimulant, to the lengths of the culturing period nor to the presence of prostaglandins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02429055
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  • 9
    Electronic Resource
    Electronic Resource
    Lysinuric protein intolerance and systemic lupus erythematosus (1998)
    Springer
    European journal of pediatrics 157 (1998), S. 130-131 
    Details
    ISSN: 1432-1076
    Keywords: Key words Lysinuric protein intolerance ; Systemic lupus erythematosus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report lysinuric protein intolerance (LPI) and systemic lupus erythematosus (SLE) in a 14-year-old girl. The co-existence of LPI and SLE in the same patient has been reported before and suggests that SLE is directly connected with LPI. Conclusion Possibly in LPI the metabolic derangement can cause immunological abnormalities. Therefore, when multisystem involvement is observed in LPI patients, SLE should be considered as a rare complication.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004310050784
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  • 10
    Electronic Resource
    Electronic Resource
    Technology in emulsified particle size control by new mixing method (2005)
    Oxford, UK : Blackwell Science Ltd
    International journal of cosmetic science 27 (2005), S. 0 
    Details
    ISSN: 1468-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The best pulverization of emulsions that can be achieved using conventional mixing blades is in the micrometer realm. Now, with our new ‘thin-film spin system’ high-speed mixer, it is possible to attain pulverization in the nanometer realm. The particle size distribution can now be controlled to achieve an almost single distribution state. Particles can be pulverized without being severed, preventing secondary agglomeration after processing. This new mixing system also solves many of the problems common to conventional pulverization processes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1463-1318.2005.00273_4.x
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