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  • 1
    Electronic Resource
    Electronic Resource
    Noradrenergic modulation of calcium currents and synaptic transmission in the olfactory bulb of Xenopus laevis tadpoles (2001)
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 13 (2001), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Norepinephrine (NE) has various modulatory roles in both the peripheral and the central nervous systems. Here we investigate the function of the locus coeruleus efferent fibres in the olfactory bulb of Xenopus laevis tadpoles. In order to distinguish unambiguously between mitral cells and granule cells of the main olfactory bulb and the accessory olfactory bulb, we used a slice preparation. The two neuron types were distinguished on the basis of their location in the slice, their typical branching pattern and by electrophysiological criteria. At NE concentrations lower than 5 µm there was only one effect of NE upon voltage-gated conductances; NE blocked a high-voltage-activated Ca2+-current in mitral cells of both the main and the accessory olfactory bulbs. No such effect was observed in granule cells. The effect of NE upon mitral cell Ca2+-currents was mimicked by the α2-receptor agonists clonidine and α-methyl-NE. As a second effect, NE or clonidine blocked spontaneous synaptic activity in granule cells of both the main and the accessory olfactory bulbs. NE or clonidine also blocked the spontaneous synaptic activity in mitral cells of either olfactory bulb. The amplitude of glutamate-induced currents in granule cells was modulated neither by clonidine nor by α-methyl-NE. Taken together, the main effect of the noradrenergic, presynaptic, α2-receptor-mediated block of Ca2+-currents in mitral cells appeared to be a wide-spread disinhibition of mitral cells in the accessory olfactory bulb as well as in the main olfactory bulb.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.0953-816x.2001.01479.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Tyrosine hydroxylase-negative, dopaminergic neurons are targets for transmitter-depleting action of haloperidol in the snail brain (1996)
    Springer
    Cellular and molecular neurobiology 16 (1996), S. 451-461 
    Details
    ISSN: 1573-6830
    Keywords: antipsychotic ; neuroleptic ; gastropod ; monoamine ; catecholamine ; serotonin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary 1. The effects of long term administration of micromolar concentrations of the D2 antagonist haloperidol upon monoaminergic neurons in the snailLymnaea stagnalis was investigated. 2. Treatment by bath application with 0.5–2.0 micromolar haloperidol, caused a significant, continuous depletion of dopamine levels in the nervous system as revealed by high performance liquid chromatography. 3. A transient depletion of serotonin was also observed, but DOPA and norepinephrine levels were unaffected. Similar depletion of dopamine was observed after the land snail,Achatina fulica, was injected with haloperidol on each of 4 consecutive days. 4. The depletion of dopamine as revealed with glyoxylate-induced fluorescence inLymnaea appears to be restricted to a subpopulation of catecholaminergic neurons which are immuno-negative for tyrosine hydroxylase, the synthetic enzyme responsible for the conversion of tyrosine to DOPA.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02150226
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Immunolabeled neuroactive substances in the osphradium of the pond snail Lymnaea stagnalis (1994)
    Springer
    Cell & tissue research 275 (1994), S. 269-275 
    Details
    ISSN: 1432-0878
    Keywords: Enkephalins ; FMRFamide ; Serotonin (5HT) ; Immunocytochemistry ; Sensory organ ; Osphradium ; Lymnaea stagnalis (Mollusca)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The osphradium of molluscs is assumed to be a sensory organ. The present investigation in Lymnaea stagnalis has established two ultrastructurally different types of dendrites in the sensory epithelium. Cells immunoreactive to leucine-enkephalin and FMRFamide send processes to the sensory epithelium. These neurons of the osphradial ganglion are thus considered to be part of the sensory system, as are methionine-enkephalin-immunoreactive cells in the mantle wall in the vicinity of the osphradium. The complexity of the osphradial ganglion is further demonstrated by serotonin-immunoreactive neurons innervating the muscular coat around the osphradial canal and methionine-enkephalin-immunoreactive cells sending projections to the central nervous system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00319424
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Serotonin-and FMRFamide-immunoreactive nerve elements in the chiton Lepidopleurus asellus (Mollusca, Polyplacophora) (1994)
    Springer
    Cell & tissue research 275 (1994), S. 277-282 
    Details
    ISSN: 1432-0878
    Keywords: Serotonin (5HT) ; FMRFamide ; Immunocytochemistry ; Invertebrate nervous system ; Chiton, Lepidopleurus asellus (Mollusca)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The distribution of serotonin-like and FMRFamide-like immunoreactive (5HT-ir and FMRFa-ir, respectively) neurons in the nervous system of the chiton Lepidopleurus asellus (Mollusca, Polyplacophora) was studied using an immunocytochemical technique. The neurons were distributed in characteristic patterns in the central nervous system, the 5HT-ir neurons predominating in the ventral (pedal) cords and FMRFa-ir neurons in the lateral cords. In the body wall including the foot, a tight network of 5HT-ir and FMRFa-ir nerve fibers is found, the former being mostly attributed to the musculature whereas the latter seems to be associated with the blood sinuses. Intraepithelial neurons of both types are abundant in the fore-and hindgut. The presence and general distribution in the central and peripheral nervous system of the 5HT-ir and FMRFa-ir elements seems thus to be similar in simple and advanced molluscs. The relationship between these neurons and their targets in the body also appears to be well conserved in molluscs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00319425
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    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Immunolabeled neuroactive substances in the osphradium of the pond snail Lymnaea stagnalis (1994)
    Springer
    Cell & tissue research 275 (1994), S. 269-275 
    Details
    ISSN: 1432-0878
    Keywords: Key words: Enkephalins – FMRFamide – Serotonin (5HT) – Immunocytochemistry – Sensory organ – Osphradium –Lymnaea stagnalis (Mollusca)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. The osphradium of molluscs is assumed to be a sensory organ. The present investigation in Lymnaea stagnalis has established two ultrastructurally different types of dendrites in the sensory epithelium. Cells immunoreactive to leucine-enkephalin and FMRFamide send processes to the sensory epithelium. These neurons of the osphradial ganglion are thus considered to be part of the sensory system, as are methionine-enkephalin-immunoreactive cells in the mantle wall in the vicinity of the osphradium. The complexity of the osphradial ganglion is further demonstrated by serotonin-immunoreactive neurons innervating the muscular coat around the osphradial canal and methionine-enkephalin-immunoreactive cells sending projections to the central nervous system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00319424
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Serotonin- and FMRFamide-immunoreactive nerve elements in the chiton Lepidopleurus asellus (Mollusca, Polyplacophora) (1994)
    Springer
    Cell & tissue research 275 (1994), S. 277-282 
    Details
    ISSN: 1432-0878
    Keywords: Key words: Serotonin (5HT) – FMRFamide – Immunocytochemistry – Invertebrate nervous system – Chiton, Lepidopleurus asellus (Mollusca)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. The distribution of serotonin-like and FMRF-amide-like immunoreactive (5HT-ir and FMRFa-ir, respectively) neurons in the nervous system of the chiton Lepidopleurus asellus (Mollusca, Polyplacophora) was studied using an immunocytochemical technique. The neurons were distributed in characteristic patterns in the central nervous system, the 5HT-ir neurons predominating in the ventral (pedal) cords and FMRFa-ir neurons in the lateral cords. In the body wall including the foot, a tight network of 5HT-ir and FMRFa-ir nerve fibers is found, the former being mostly attributed to the musculature whereas the latter seems to be associated with the blood sinuses. Intraepithelial neurons of both types are abundant in the fore- and hindgut. The presence and general distribution in the central and peripheral nervous system of the 5HT-ir and FMRFa-ir elements seems thus to be similar in simple and advanced molluscs. The relationship between these neurons and their targets in the body also appears to be well conserved in molluscs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00319425
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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