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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 117 (1992), S. 200-205 
    ISSN: 0942-0940
    Keywords: Barbiturate therapy ; cerebro-vascular resistance ; dopamine ; oxygen extraction fraction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of barbiturates on the cerebral haemodynamics and the influence of dopamine on barbiturates were investigated using 20 cats, and clinical indication of barbiturate therapy is discussed. Cerebral blood flow, oxygen extraction fraction, and cerebro-vascular resistance as well as physiological variables were evaluated at various concentrations of barbiturates in the blood. Thiamylal caused simultaneous reduction of mean arterial blood pressure and cerebral blood flow. As the disruption of autoregulation proceeded, cerebro-vascular resistance and oxygen extraction fraction increased till the barbiturate-induced coma stage. Furthermore, cerebro-vascular resistance increased much more markedly by the combined use of dopamine. Clinically, our results indicate barbiturates would increase cerebral circulatory disturbances caused by vasospasm following subarachnoid haemorrhage because barbiturates further increase cerebro-vascular resistance. Then again, the combined use of dopamine is not preferable because of deterioration in vasospasm.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0942-0940
    Keywords: Barbiturate therapy ; cerebral metabolism ; dopamine ; electro-encephalogram
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of dopamine during barbiturate therapy was investigated in 29 cats including 5 sham-operated cats. According to Kiersey's classification of electro-encephalographic patterns, physiological variables, cerebral metabolic rates for oxygen and glucose, cerebral blood flow (CBF), and intracranial pressure (ICP), etc. were evaluated in each electro-encephalographic pattern. Oxygen-glucose index was calculated and used as an indicator for aerobic or anaerobic metabolism of glucose. Group 1 (12 cats), to which only thiamylal was administered, maintained aerobic glycolysis due to a parallel reduction of cerebral metabolic rates for oxygen and glucose (about half of the initial value at Kiersey's fifth pattern) in spite of reduction of CBF and mean arterial blood pressure (MABP). Group 2 (12 cats), to which dopamine was administered in addition to thiamylal due to a reduction of MABP, showed anaerobic glycolysis though MABP and CBF were maintained. These findings are ascribed to an increase of cerebral metabolic rate for glucose up to 130% of the initial value though cerebral metabolic rate for oxygen decreased down to half of the initial value: The beneficial effect of barbiturate on cerebral metabolism was reduced by use of dopamine. ICP was reduced in both groups. Our result indicates that administration of extracellular fluid may be preferable for treatment of hypotension during barbiturate therapy than dopamine medication.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0942-0940
    Keywords: Primary intracranial malignant melanoma ; Longterm survival
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A 57-year-old male with primary intracranial malignant melanoma who survived 9 years and 6 months is reported. He underwent surgical removal of the tumour three times during the decade 1978 to 1988, and received chemo-immuno-radiotherapy during that time. Acute tumour growth, suggesting tumour dissemination, was seen in the CT scans after the third removal of recurrent tumour, but then it disappeared after combined chemoradiotherapy with DTIC. He gradually became inactive, probably because of brain atrophy caused by high-dose radiotherapy and chemotherapy, and died of renal failure without any sign of recurrence on CT scans.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0960-894X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0040-4020
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 0040-4039
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Tetrahedron Letters 25 (1984), S. 3873-3874 
    ISSN: 0040-4039
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Fresenius' Zeitschrift für analytische Chemie 320 (1985), S. 573-576 
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Summary A liquid-membrane type diethyldithiocarbamate ion-selective electrode (DDC-ISE) was constructed by utilizing the nitrobenzene extract of the methyltrioctylammonium-DDC ion-pair. The DDC-ISE shows Nernstian response in the concentration range of 10−5–10−1 M DDC in 0.1 M sodium hydroxide solution. The electrode potential is constant in the pH range of 7.6–13.0. Potentiometric titrations of Hg(II), Cu(II), Ni(II) and Zn(II) in ammoniacal solutions with NaDDC and successive titration of two binary systems, Hg(II)-Ni(II) and Hg(II)-Zn(II), were successfully carried out with this electrode.
    Notes: Zusammenfassung Eine Diethyldithiocarbamat-ionenselektive Flüssig-Membranelektrode (DDC-ISE) wurde entwickelt, die den Nitrobenzolextrakt des Ionenpaares Methyltrioctylammonium-DDC benutzt. Die DDC-ISE zeigt Nernstsches Ansprech-Verhalten im Konzentrationsbereich von 10−5–10−1 M DDC in 0,1 M Natriumhydroxidlösung. Das Elektrodenpotential ist im pH-Bereich von 7,6–13,0 konstant. Potentiometrische Titrationen von Hg(II), Cu(II), Ni(II) und Zn(II) mit NaDDC in ammoniakalischer Lösung sowie sukzessive Titrationen der binären Systeme Hg(II)-Ni(II) und Hg(II) — Zn(II) wurden erfolgreich durchgeführt.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1573-5052
    Keywords: Guild structure ; Historical events ; Non-equilibrium coexistence ; Regeneration niche ; Markov model
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Species assembly and niche differentiation were studied, and future species composition was predicted by simple Markov models, in an old-growth deciduous forest at the Ogawa Forest Reserve in central Japan. The dominant species in our 6ha study site are Quercus serrata, Fagus japonica, and F. crenata. An ordination by population parameters revealed four different combination 3 of life forms and regeneration niches. Cluster analysis based on interspecific spatial correlation revealed three groups of species. The species in cluster A, such as F. japonica, occurred at the bottom of the valley, while those in cluster B, such as Q. serrata, occurred along ridges. Species in cluster C, such as F. crenata, did not show any particular habitat preference. Clusters B and C were further divided into three smaller clusters (a-c). Both clusters Ba and Bb included shade intolerant species. Species in cluster Ba had large clump sizes (〉1500 m2), reflecting regeneration following large-scale disturbances. Species in cluster Bb had smaller clump sizes (〈400 m2) reflecting regeneration following local disturbances. Clusters Ca and Cb mainly included shade tolerant species and shade intolerant species, respectively. Markov models predicted that shade intolerant species, particularly those in cluster Ba, would be eliminated. Thus, species coexist by differentiation of both habitats and regeneration niche in this forest community. Some species such as Quercus serrata, however, regenerate following large-scale disturbances or human activity.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1573-5052
    Keywords: Canopy gap ; Community dynamics ; Deciduous forest ; Disturbance ; Ogawa Forest Reserve ; Permanent plot
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Forest community dynamics were studied for 4 years in a 6 ha permanent plot of species rich, old-growth, temperate deciduous forest in Ogawa Forest Reserve, central Japan. The gap formation rate, recruitment, mortality, gain and loss rate in basal area during 4 years were 42 m2 ha−1 yr−1, 1.74% yr−1, 1.19% yr−1, 1.12% yr−1 and 0.88% yr−1, respectively. The turnover time calculated from them ranged from 58 to 240 years. Both the mortality and mortality factors were size dependent; trees in middle size class had smallest mortality, and the proportion of the trees killed by disturbances increased with size. Gap creations were concentrated in a particular year, suggesting a large heterogeneity in time. Spatial distribution of recruited trees were biassed to the old gaps (older than 4 years), especially that of the species with Bell-shaped dbh distribution (shade intolerant) strongly associated with the gaps. Recruitment in tree stems and the loss of basal area, thus had the larger variability than mortality of stems and this forest, and the species with L-shaped dbh distribution seemed to going to increase the importance in the future if the present trend continues to be held. The turnover time of population is positively correlated with the maximum dbh size of the species, indicating the slow change of the population of large sized species.
    Type of Medium: Electronic Resource
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