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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Histopathology 37 (2000), S. 0 
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The recognition of recurrent genetic alterations in specific tumour types has provided the basis for the reclassification of certain soft tissue neoplasms, and molecular analysis of patient material has the potential to provide both diagnostic and prognostic information. In this review, we evaluate the role of molecular genetic testing as the prospective ‘gold standard’ for sarcoma diagnosis. Molecular genetic testing, as with every new method, promises to improve accuracy and to be more sensitive and less subjective, claims that have been made previously by histochemistry, electron microscopy and immunohistochemistry. Technical limitations in molecular assays, as well as more general specificity issues, decrease the clinical usefulness of molecular pathological testing significantly and suggest that, at present, molecular evaluation is best considered an ancillary technique that neither supersedes other ancillary techniques nor eclipses traditional pathological examination.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of organic chemistry 35 (1970), S. 2043-2044 
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford UK : Blackwell Science Ltd
    Histopathology 39 (2001), S. 0 
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Transport in porous media 6 (1991), S. 241-259 
    ISSN: 1573-1634
    Keywords: Fractures ; tracer ; Wairakei ; Palinpinon ; geothermal reservoirs ; numerical
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Technology
    Notes: Abstract The most important results from a tracer test are whether or not tracer is detected at each observation well and the travel times to the wells that respond. A method developed by the authors for accurately calculating travel times for tracer movement in general flow fields enables the locations of major fractures in a reservoir to be deduced from the travel-time data. The procedure is applied here to data from Wairakei, New Zealand, and Palinpinon, Philippines.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Transport in porous media 1 (1986), S. 293-312 
    ISSN: 1573-1634
    Keywords: Convection ; geothermal heat transfer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Technology
    Notes: Abstract For a uniform saturated porous layer heated from below, the dependence of the quantity of heat transferred on the distribution of the heat source is investigated. It is found, using perturbation methods and numerical techniques, that very small nonuniformities in the heat source having the same wavelength as the preferred convection mode significantly reinforce natural convection.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1573-1634
    Keywords: Geothermal heat pipe ; upstreaming, stability ; solution selection ; boundary conditions ; steady state ; two-phase counterflow
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Technology
    Notes: Abstract In a geothermal reservoir, the heat pipe mechanism can transfer heat very efficiently, with vapor rising and liquid falling in comparable quantities, driven by gravity. For a given heat and mass flux that is not too large, there are two possible steady solutions with vapor-liquid counterflow, one liquid-dominated, and one vapor-dominated. Numerical solution of the equations for two-phase vertical counterflow displays intriguing stability behaviour. If pressure and saturation are fixed at depth, and heat and mass flux specified at the top, the vapor-dominated solution is almost always obtained. That is, for a variety of boundary values, the solution settles to the vapor-dominated steady-state, and only for very special values is it possible to obtain the liquid-dominated case. Similarly the liquid-dominated solution is almost always obtained if the boundary conditions are reversed, with pressure and saturation fixed at the top and heat and mass flux specified at depth. This behaviour is here explained in two complementary ways. It is shown to be a consequence of upstream differencing of the flow terms in the numerical method. It is also shown to be expected behaviour for wavelike saturation solutions. Hence the observed behaviour is not only a direct consequence of the numerical method used, but is fundamental to geothermal heat pipes.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Transport in porous media 2 (1987), S. 497-517 
    ISSN: 1573-1634
    Keywords: Geothermal ; well test analysis ; fractured reservoirs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Technology
    Notes: Abstract Several numerical experiments comparing the response of a fractured geothermal reservoir with that of a uniform reservoir are reported. A constant rate drawdown test followed by a buildup test is investigated for both an initially two-phase reservoir and an initially liquid reservoir which flashes during the test. Also, cold water injection into a two-phase reservoir is considered. In all cases the fracturing of the reservoir significantly changes the results for the uniform reservoir, and makes interpretation of the well test results more difficult.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Transport in porous media 6 (1991), S. 261-280 
    ISSN: 1573-1634
    Keywords: Fractures ; tracer ; geothermal reservoirs ; numerical ; potential flow
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Technology
    Notes: Abstract A new method is presented for calculating the time taken for tracer to move between wells in a fractured geothermal reservoir. The reservoir model considered is a two-dimensional confined layer, but many wells and a background regional flow can be included. Also, either a straight or dog-leg, finite length, high permeability fracture can be included. The fracture can alternatively be considered as a barrier to lateral flow. The flow field is represented by complex potentials which are used to accurately calculate the streamline locations and tracer travel times are evaluated by numerical integration along the streamlines. The methods developed are used to model the dispersion of tracer produced by large-scale differences in the flow paths along which the tracer travels from the release well to the observation well(s).
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 3 (1979), S. 355-366 
    ISSN: 0363-9061
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: Two finite difference algorithms suitable for long-time simulation of the exploitation of a two-phase geothermal reservoir are presented. One is based on the hopscotch method proposed by Saul'yev1 and analysed further by Gordon2 and Gourlay.3 The other is based on the well-known ADI method. Both methods use a Newton-Raphson iterative technique in order to obtain accurate solutions of the non-linear difference equations involved. Rapid convergence of the iterative schemes occurs both for single-phase and two-phase reservoir problems. One- and two-dimensional model problems are presented.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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