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  • 1
    Electronic Resource
    Electronic Resource
    Differential modulation by betamethasone of allergen-induced cell influx and cell peroxidase in guinea-pig lungs (1995)
    Springer
    Inflammation research 44 (1995), S. S177 
    Details
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01778319
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  • 2
    Electronic Resource
    Electronic Resource
    Effects of two cytostatics (degranol and bleomycin) on the chromosomes of human lymphocytes in culture
    Amsterdam : Elsevier
    Mutation Research/Environmental Mutagenesis and Related Subjects 74 (1980), S. 219 
    Details
    ISSN: 0165-1161
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0165-1161(80)90100-4
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  • 3
    Electronic Resource
    Electronic Resource
    Speech sound distortions caused by changes in complete denture morphology (1985)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 12 (1985), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A numerical method for speech analysis has been developed. The method is based on sounds spectrograms as carriers of information about individual voice characteristics.The effects on speech sounds caused by alterations of the oral cavity dimensions with complete dentures of different morphology were analysed. Different positions of upper incisors and different thickness of the denture palatal plate were used as changeable factors in the longitudinal and transverse dimensions of the oral cavity. The effects of these changes on the relative duration of separate sounds in a word and the patient adaptation period were also analysed.From the results some conclusions of pragmatic value were obtained useful in the clinical procedures of denture construction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2842.1985.tb00622.x
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  • 4
    Electronic Resource
    Electronic Resource
    The karyotype of the parthenogenetic Artemia (Crustacea) from Secovlje, Yugoslavia (1991)
    Springer
    Genetica 83 (1991), S. 289-291 
    Details
    ISSN: 1573-6857
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The karyotype of a parthenogenetic population of Artemia sp. living in the 289-2 saltwork is tetraploid. It consists of 84 chromosomes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00126234
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  • 5
    Electronic Resource
    Electronic Resource
    Morphological evidence of a polypeptide-like secretory function of the B cells in the mouse synovial membrane (1977)
    Springer
    Cellular and molecular life sciences 33 (1977), S. 1098-1099 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In the synovial membrane of the mouse, morphological features associated with acitve secretion are unusually well developed in cells immediately subjacent to the lining layer (in the position of B cells), comparable to those of cells known to elaborate polypeptides.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01945993
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  • 6
    Electronic Resource
    Electronic Resource
    Effect of BW B70C, a novel inhibitor of arachidonic acid 5-lipoxygenase, on allergen-induced bronchoconstriction and late-phase lung eosinophil accumulation in sensitised guinea-pigs (1993)
    Springer
    Inflammation research 38 (1993), S. 8-18 
    Details
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The actions of BW B70C, an orally available, biologically persistent and selective inhibitor of arachidonic acid 5-lipoxygenase, have been examined in two systems of anaphylaxis in actively sensitised guinea-pigsin vivo. In anaesthetised, artificially ventilated animals pretreated with mepyramine and indomethacin to leave only the “peptidoleukotriene-dependent” component (leukotrienes C4, D4 and E4) of the anaphylactic response, direct inhalation of nebulised, allergen resulted in a slowly developing bronchoconstriction which was prevented in a dose-dependent manner, by BW B70C (2–50 mg/kg p.o.) administered 1 or 6 h before challenge. In conscious animals fasted overnight and then pretreated with mepyramine to prevent death due to acute bronchial anaphylaxis, exposure to nebulised, allergen produced slight respiratory symptoms. When blood and lung samples were analysed 4–48 h after allergen provocation a sustained leukocytosis and pulmonary eosinophil accumulation were observed. In contrast, in food-replete conscious animals, the early respiratory symptoms were still observed upon allergen inhalation, but no significant blood leukocytosis or accumulation of eosinophils in the lungs occurred subsequently. The eosinophil influx induced by allergen in fasted animals was assessed both by histological examination and determination of tissue peroxidase content, two measures which demonstrated reasonable agreement. Administration of a single dose of BW B70C (10 mg/kg p.o.) 1 h prior to allergen challenge did not affect the subsequent eosinophil infiltration 24 h later, but 20 mg/kg given in divided doses (−1 and +12 h) produced 67% inhibition of cell accumulation. A single dose of 50 mg/kg (−1 h) had a similar effect (78% inhibition). The potent glucocorticosteroid betamethasone was used as a reference compound, and 4 mg/kg given as a divided dose (−1 and +7) fully inhibited lung inflammation assessed 24 h after provocation with allergen. BW B70C inhibited both acute and allergic bronchoconstriction and late-phase eosinophil accumulation subsequent to allergen inhalation in guinea-pigs. In view of the apparent requirement for sustained plasma levels of BW B70C in order to prevent late-phase eosinophil recruitment to the lung after a single challenge with allergen, it is unclear whether inhibition of 5-lipoxygenase underlies the observed anti-eosinophil accumulation effects of the compound, but the anti-bronchoconstrictor effects are consistent with the known inhibitory activity of BW B70C against 5-lipoxygenase.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02027207
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  • 7
    Electronic Resource
    Electronic Resource
    Synthesis and molecular structure of salicylaldehydeS-methyl-isothiosemicarbazone, C9H11N3OS (1983)
    Springer
    Monatshefte für Chemie 114 (1983), S. 1205-1211 
    Details
    ISSN: 1434-4475
    Keywords: Crystal structure analysis ; Salicylaldehyde S-methylisothiosemicarbazone
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Salicylaldehyd-S-methylisothiosemicarbazon wurde dargestellt und die Kristallstruktur vermessen: C9H11N3OS, monoklin, P21/n,a=5,169(4),b=16,853(10),c=11,367(5)Å, β=92,48(1)°,V=989,3(18)Å3,Z=4,d x =1,405 g cm−3. Die Struktur wurde mit Hilfe derPatterson-undFourier-Methode bestimmt und anisotropisch bis zu einemR-Wert von 0,046 verfeinert. Das Molekül ist praktisch eben, wobei ein grundlegender Unterschied zwischen der protonierten (H2 L) und der deprotonierten Form in den Komplexver-bindungen besteht. Die Formen unterscheiden sich durch eine Drehung um ca. 180° um die C1—N2-Doppelbindung. Die Moleküle H2 L sind durch Wasserstoffbindungen um das Symmetriezentrum zu einem Dimeren verknüpft.
    Notes: Abstract The crystal structure of salicylaldehyde S-methylisothiosemicarbazone together with the synthesis applied are reported: C9H11N3OS, monoclinic, P21/n,a=5.169(4),b=16.853 (10),c=11.367(5)Å, β=92.48(1)°,V=989.3(18)Å3,Z=4,d x =1.405g cm−3. The structure was solved by the heavy atom method and refined anisotropically to a residualR=0.046. The molecule is practically co-planar. There is only one basic difference between the title compound H2 L and its deprotonated and complexed forms reported hitherto: the nearly 180° difference in rotation about the formal double bond C1—N2. The molecules form hydrogen bonded dimers around $$\bar 1$$ .
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00799934
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  • 8
    Electronic Resource
    Electronic Resource
    Thermal stability of the amorphous system As-Se-I (1990)
    Springer
    Journal of thermal analysis and calorimetry 36 (1990), S. 2375-2382 
    Details
    ISSN: 1572-8943
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Mittels DTA und DDTA wurde untersucht, wie die Zugabe von Jod zu dem binären System As-Se die thermische Stabilität der so gebildeten ternären Gläser beeinflußt. Die untersuchten Gläser entsprechen verschiedenen Regionen des Phasendiagrammes, d.h. sie besitzen einen unterschiedlichen As- bzw. I-Gehalt und enthielten unterschiedlich geartete Struktureinheiten. Bei den untersuchten jodhaltigen ternären Systemen tritt der Kristallisationseffekt bei niedrigeren Temperaturen auf als bei den binären Gläsern As40Se60, das gleiche gilt für die Schmelz- als auch für die Erweichungstemperatur. Sowohl bei den binären als auch bei den ternären Systemen wurde die Aktivierungs energie für den Kristallisationsprozeß ermittelt. Das Glas As40Se60 zeigte eine etwas höhere Aktivierungsenergie, d.h. eine etwas geringere Neigung zur Kristallisation als das ternäre System. Für die kritische Abkühlgeschwindigkeit der Schmelzen zum Erreichen eines minimalen Kristallinitätsgrades wurden bei den binären (As2Se3) und ternären (AsSeI) Systemen annähernd gleiche Werte bestimmt.
    Notes: Abstract The effect of adding iodine to the binary systems As-Se on the thermal stability of the ternary glasses thus formed was investigated by DTA and DDTA. The investigated glasses corresponded to different regions of the phase diagram, i.e. they had different contents of As and I and, consequently, contained different types of structural units. In the investigated ternary systems with iodine, the crystallization effect appears at a lower temperature than in the binary glass As40Se60, and the same holds for the temperatures of softening and melting. For both binary and ternary systems, the activation energies of crystallization were determined. The glass As40Se60 exhibited a somewhat higher activation energy, i.e. a somewhat lower tendency to crystallize than the ternary system. The critical cooling rates of the melts for minimum degree of crystallinity were estimated. The obtained values are approximately equal for the binary (As2Se3) and ternary (AsSeI) systems.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01913635
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  • 9
    Electronic Resource
    Electronic Resource
    Transition metal complexes with hydrazides and hydrazones (1990)
    Springer
    Journal of thermal analysis and calorimetry 36 (1990), S. 2483-2492 
    Details
    ISSN: 1572-8943
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Sowohl in Luft als auch in Stickstoffatmosphäre wurde die thermische Zersetzung von oktaedrischen Co(II)-Komplexen der allgemeinen Formel CoLnX2· mH2O (n=2 und 3,m=1, 2 und 5,X=Cl, Br, I, NCS, OAc und SO4) untersucht. Es wurde festgestellt, daß sich die Komplexe unterhalb 800°C vollkommen zu CoO als Endprodukt zersetzen. Der wahrscheinlichste Zersetzungsmechanismus wurde unterbreitet. Die tris-Ligandenkomplexe wurden mittels Elementaranalyse sowie Spektral- und magnetischen Untersuchungen charakterisiert, alle Angaben deuten auf eine Punktsymmetriegruppe vom Typ Oh hin.
    Notes: Abstract A study was made of the thermal decomposition of octahedral Co(II) complexes of the type CoLn X 2·mH2O, wheren=2 and 3,m=1,2 and 5 andX=Cl, Br, I, NCS, OAc andv 2So4, in both air and nitrogen atmospheres. It was established that the complexes are completely decomposed below 800° and CoO is formed as final product. The most probable decomposition mechanism was proposed. The tris(ligand) complexes were characterized by elemental analysis, and spectral and magnetic measurements, and all the data suggested the presence of a point group symmetry of type Oh.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01913645
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  • 10
    Electronic Resource
    Electronic Resource
    Metal complexes with pyrazole-derived ligands (1996)
    Springer
    Journal of thermal analysis and calorimetry 47 (1996), S. 879-886 
    Details
    ISSN: 1572-8943
    Keywords: complexes ; cobalt(II) ; 3(5)-amino-4-acetyl-5(3)-methilpyrazole ; thermal decomposition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The thermal decomposition of tetrahedral cobalt(II) complexes with 3(5)-amino-4-acetyl5(3)-methylpyrazole (HL) of the general formula [Co(HL)2X2] (X=Cl, Br, I, NCO, NCS) and octahedral [Co(HL)2(H2O)4](NO3)2 and [Co(HL)2−N(CN)2}2] complexes was investigated in air atmosphere in the interval from room temperature to 1000°C. Decomposition of the complexes occurred in several successive endothermic and exothermic processes, and the residue was in all cases CoO.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01981822
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