ISSN:
1573-6822
Keywords:
cultured liver cells
;
chromosomal aberrations
;
structure-activity relationship
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Four regioisomeric phenanthrene (PH) quinones (Q) were investigated for their ability to induce chromosomal damage and spindle disturbances. PH 1,4-Q and PH 1,2-Q induced structural as well as numerical chromosomal aberrations, whereas the isomers PH 9,10-Q and PH 3,4-Q were virtually inactive in this respect. However, all four compounds enhanced the frequency of c-mitoses.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1007302111081
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