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  • 1
    Electronic Resource
    Electronic Resource
    Ectopic action potential generation: its occurrence in a chronic epileptogenic focus (1985)
    Springer
    Experimental brain research 60 (1985), S. 599-602 
    Details
    ISSN: 1432-1106
    Keywords: Experimental epilepsy ; Ectopic action potential generation ; Bursting behavior ; Rat neocortex ; Cobalt
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Intracortical axon terminals of thalamocortical relay neurons projecting into chronic cortical epileptogenic foci may generate high frequency bursts of action potentials during spontaneous cortical epileptiform paroxysms. Such bursts occur regularly before onset of the corresponding surface paroxysms in a large proportion of the tested neurons. Therefore, such axon terminals bursting may participate in the triggering of the synchronous, prolonged intracellular depolarization shifts which are observed in cortical neurons during epileptic events.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00236948
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Extracellular calcium activity changes in cat sensorimotor cortex induced by iontophoretic application of aminoacids (1980)
    Springer
    Experimental brain research 40 (1980), S. 247-250 
    Details
    ISSN: 1432-1106
    Keywords: Extracellular Ca2+ activity ; Cerebral cortex ; Excitatory aminoacids ; Ca2+ antagonists ; GABA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Extracellular Ca2+ activity (aCa) changes were measured with Ca2+-sensitive microelectrodes in the cat cerebral cortex during iontophoretic administration of excitatory and inhibitory aminoacids. Glutamate, aspartate and DL homcysteate usually decreased aCa from a baseline of 1.3 mM to as low as 0.1 mM. The amplitude of the changes was largest at depths between 100 and 300 μm beneath the cortical surface. The aCa decreases could be deminished or blocked by Co2+, Mn2+ or La3+ as well as by GABA. These data suggest that large Ca2+ conductances that may be voltage-sensitive are present in apical dendrites of neocortical neurones.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00237788
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Doubtful Value of Bicuculline as a Specific Antagonist of GABA (1970)
    [s.l.] : Nature Publishing Group
    Nature 228 (1970), S. 675-676 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The tests were performed as follows. A given unit was excited in a regular manner by 4-6 s applications of L-glutamate (20-60 nA) at intervals of some 5 s (Figs. 1 and 2). The glutamate-evoked responses were then depressed to a various extent by different amounts of GABA applied for 30-40 s; in ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/228675a0
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Unexpected Features of the Action of Dinitrophenol on Cortical Neurones (1970)
    [s.l.] : Nature Publishing Group
    Nature 228 (1970), S. 562-564 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Nishi, Soeda and Koketsu8, and Kawamura and K. K.7 recently showed that in sympathetic ganglia and the cerebral cortex, DNP readily blocks the slow excitatory muscarinic action of acetylcholine (ACh). This observation seemed to confirm the hypothesis that in this muscarinic role? ACh has a primary ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/228562a0
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  • 5
    Electronic Resource
    Electronic Resource
    Activation of purkinje neurons through climbing fibres after chronic lesions of the olivo-cerebellar pathway (1968)
    Springer
    Cellular and molecular life sciences 24 (1968), S. 914-916 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Résumé Les décharges évoquées dans les cellules de Purkinje lors de l'activation des fibres grimpantes ont été testées par stimulation afférente dans un groupe d'animaux intact et dans un groupe d'animaux avec lésion chronique totale et bilatérale de la voie olivo-cerebelleuse. On a démontré qu'une partie seulement des fibres qui atteignent la région vermienne du lobe postérieur du cervelet ont leur origine dans l'olive inférieure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02138651
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    Paper (German National Licenses)
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