ISSN:
0170-2041
Keywords:
Fungicides
;
Silanes
;
Siloxanes
;
1,2,4-Triazoles
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Synthesis of Fungicidal (1H-1,2,4-Triazol-1-yl-methyl)silanes and -siloxanesThe synthesis of FlusilazoleTM (1a) was substantially improved by thorough exclusion of oxygen nucleophiles in the reaction of (chloromethyl)bis(4-fluorophenyl)methylsilane with sodium 1H-1,2,4-triazolide. New α,α-diaryl-α-(1H-1,2,4-triazol-1-yl-methyl)siloxanes 3 were obtained firstly from diaryl(1H-1,2,4-triazol-1-yl-methyl)silanols or -silanolates, which were prepared by different methods from the corresponding silanol hydrochlorides and further treated with functional, linear oligodimethylsiloxanes or secondly from α,α-diaryl-α-(chloromethyl)siloxanes and 1-(trimethylsilyl)-1H-1,2,4-triazole. The siloxane 4 containing a triazolylmethyl group and additionally silicofunctional coupling groups could be synthesized by hydrosilylation of an α-triazolylmethyl-ω-vinylsiloxane with triethoxysilane.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.199419940207
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