Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
Alimentary pharmacology & therapeutics
5 (1991), S. 0
ISSN:
1365-2036
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
The effect of cisapride on duration of post-operative ileus after surgery was investigated in a randomized, double-blind, placebo-controlled study. Patients undergoing elective upper gastrointestinal (n= 47) or colonic (n= 22) surgery were pre-operatively randomly allocated to treatment with either cisapride 30 mg t.d.s., by rectal administration, or placebo. Treatment started exactly 48 h after surgery if the patient at this time had not passed stool. Time to passage of first stool after surgery was estimated.Mean time to passage of stool was 85 (32) h (s.d.) for cisapridetreated and 91 (43) h for placebo-treated patients. No difference between the treatment groups was noted.Treatment with cisapride did not shorten the duration of postoperative ileus after either upper gastrointestinal or colonic surgery.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1365-2036.1991.tb00519.x
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