Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The coagulation factors were estimated in 40 patients with myocardial infarction under long-term treatment with dicumarol derivatives, in 28 patients with cirrhosis of the liver, and in a group of 20 normal persons. In addition to the well-known reduction of factor II, VII, IX, and X, the myocardial infarction group showed also a moderate reduction of factors V and VIII; the liver cirrhosis group showed similar, but more pronounced changes. An unequivocal difference between the influence of coumarin and hepatogenic changes in coagulation, were found in the following points: 1. Coumarin treatment causes no decrease of the fibrinogen level, while cirrhosis of the liver showed a marked decrease of fibrinogen. 2. Under anticoagulation treatment the platelet factor 3 showed normal activity; in cirrhosis of the liver the activity of this factor often showed a strong decrease. 3. No change of the antithrombin II content was found in the anticoagulant group; antithrombin III was distinctly increased. In contrast, cirrhoses of the liver showed a decrease of the antithrombin II and, in a decompensated state, mostly also a considerable decrease of antithrombin III. In cholangitic liver cirrhoses antithrombin II was distinctly increased. Furthermore, the streptokinase resistance test was carried out in 80 normal persons, 45 patients under long-term coumarin treatment, and 20 patients with cirrhosis of the liver. In the anticoagulant group, just as in the group with cirrhosis of the liver, the mean value of this test was significantly lower than in the normal group.
    Notes: Zusammenfassung Bei 40 Patienten mit Myokardinfarkt, die unter Langzeitbehandlung mit Dicumarolderivaten standen, bei 28 Patienten mit Leberzirrhose und bei einer Gruppe von 20 Normalfällen wurden Gerinnungsfaktoren bestimmt. Neben der bekannten Verminderung der Faktoren II, VII, IX und X fand sich in der Gruppe der Myokardinfarkte auch eine mäßige Verminderung der Faktoren V und VIII; die Leberzirrhosen zeigten ähnliche, jedoch stärker ausgeprägte Veränderungen. Ein eindeutiger Unterschied zwischen Cumarin-Einfluß und hepatogen bedingten Gerinnungsveränderungen fand sich in folgenden Punkten: 1. Cumarin-Behandlung verursacht keine Erniedrigung des Fibrinogenspiegels, bei den Leberzirrhosen war das Fibrinogen deutlich vermindert. 2. Der Plättchenfaktor 3 zeigte unter Antikoagulantienbehandlung eine normale Aktivität; bei Leberzirrhosen war die Aktivität dieses Faktors oft stark eingeschränkt. 3. In der Antikoagulantiengruppe fand sich keine Veränderung des Antithrombin-II-Gehalts; das Antithrombin III war deutlich vermehrt. Demgegenüber zeigten Leberzirrhosen eine Verminderung des Antithrombins II und in dekompensiertem Zustand meist auch eine erhebliche Verminderung des Antithrombins III. Bei cholangitischen Leberzirrhosen war Antithrombin II deutlich vermehrt. Außerdem wurde bei 80 Normalfällen, 45 Patienten unter Cumarin-Langzeitbehandlung und bei 20 Leberzirrhosen der Streptokinase-Resistenztest durchgeführt. In der Antikoagulantiengruppe gleicherweise wie in der Gruppe der Leberzirrhosen lag der Mittelwert für diesen Test signifikant tiefer als bei der Gruppe der Normalfälle.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part B: Polymer Physics 31 (1993), S. 537-543 
    ISSN: 0887-6266
    Keywords: gas sorption ; diffusion in polymers ; hydrogen bonding ; copolymers ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: A series of vinyl alcohol/vinyl butyral copolymers was examined to assess the effect of internal hydrogen bonding on gas sorption and diffusion. Sorption and permeation measurements for carbon dioxide and methane were performed on four vinyl alcohol/vinyl butyral copolymers. Upon comparing the various data, it was found that hydrogen-bonded copolymers exhibit a much wider variation in diffusion coefficient than non-hydrogen-bonded copolymers. The fractional free volumes of the studied copolymers were considerably lower than expected based on values of the diffusion coefficient. This may be due to the fact that predicted occupied volumes are too large and that the effect of internal hydrogen bonding is not accounted for properly. Using a relationship between infrared spectral shift and hydrogen-bond length, fractional free volumes in the hydrogen bonded copolymers were correlated with the interatomic spacing associated with the hydrogen bond. This implies that the average length of a hydrogen bond can be used as a measure of chain packing in hydrogen-bonded polymers. © 1993 John Wiley & Sons, Inc.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part B: Polymer Physics 32 (1994), S. 131-139 
    ISSN: 0887-6266
    Keywords: hydrogen bond ; gas sorption ; gas transport ; gas permeability ; diffusion ; polymer blends ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The gas sorption behavior of CO2, C2H6, and CH4, and the gas transport behavior of CO2 and CH4, were examined for polyethersulfone (PES), polyhydroxyether, and four miscible blends containing 20, 40, 60, and 80 wt % PES. The 40 wt % PES blend exhibited the lowest sorption levels and the lowest permeabilities for all of the gases. Application of the dual-mode sorption model revealed negative deviations for the Henry's law parameter kD that were larger than those observed for blends relying on van der Waals or simple polar interactions. Also, the magnitude of the blend interaction parameter obtained from the gas sorption data and the volume of mixing were both more negative in the hydrogen-bonded blend. Diffusion coefficients at infinite dilution and from the dual mode/partial immobilization model exhibited minima at 40 wt % PES, as did the fractional free volume, a measure of chain packing ability. © 1994 John Wiley & Sons, Inc.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...