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  • 1
    Electronic Resource
    Electronic Resource
    Relation of allergy to HIV infection (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the European Academy of Dermatology and Venereology 2 (1993), S. 0 
    Details
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In this retrospective study on 141 HIV-positive subjects, allergy was studied by a specific questionnaire and the Phadia-Top-Test, an in vitro screening test detecting specific IgE; both were correlated to the patient's history, clinical symptoms and the treatment used. Allergy was studied in reference to HIV-negative controls and in relation to the clinical and biological subgroups of HIV patients.The application of the x2 test demonstrated a high incidence of allergy and a specific relation to the HIV infection compared to the controls as well as in relation to the clinical stage of the infection. Atopy was not specifically related to the HIV infection despite the higher frequency found in the AIDS-IKEL group.A significant number (21%) of patients with T4 〉 300/μ1 considered immunocompetent presented clinical manifestations of AIDS-IKEL and 100% of these patients were allergic. A significant number (19%) of patients with T4 〈 300/μ1 considered immunodeficient were asymptomatic and 75% of them were allergic.Thus allergic symptoms may transiently be the only clinical manifestations in HIV infection and possibly a co-factor for the evolution of the disease due to the immunomodulatory function of the mediators, the cytokines and the proteases released during allergic reaction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1468-3083.1993.tb00033.x
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  • 2
    Electronic Resource
    Electronic Resource
    Circulating autoantibodies in patients with fibrocystic disease of the breast (1983)
    Springer
    Journal of cancer research and clinical oncology 106 (1983), S. 219-221 
    Details
    ISSN: 1432-1335
    Keywords: Autoantibodies ; Fibrocystic disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Antinuclear, parietal-cell, smooth-muscle, mitochondrial, and adrenal antibodies were determined in the blood serum of 110 patients with fibrocystic disease of the breast and of 102 healthy blood donors by indirect immunofluorescence. Thirty-eight percent of the patients had detectable autoantibodies compared to 16% of the controls (P〈0.001). Significant differences were found in the incidence of parietal-cell and smooth-muscle autoantibodies between the patients and controls. In addition, more than one autoantibody was detected in the serum of a significantly larger number of patients than controls. The findings indicate that an immunologic mechanism is involved in the pathogenesis of fibrocystic disease of the breast.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00402611
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    Paper (German National Licenses)
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