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  • 1
    Electronic Resource
    Electronic Resource
    Stability Constants for Iodine-Aromatic Complexes in Cyclohexane. (1963)
    s.l. : American Chemical Society
    Journal of chemical & engineering data 8 (1963), S. 239-240 
    Details
    ISSN: 1520-5134
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/je60017a032
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  • 2
    Electronic Resource
    Electronic Resource
    Partition Chromatography of Yeast and Escherichia coli Soluble Ribonucleic Acid. Relation of Coding Properties to Fractionation* (1965)
    s.l. : American Chemical Society
    Biochemistry 4 (1965), S. 2412-2418 
    Details
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bi00887a022
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  • 3
    Electronic Resource
    Electronic Resource
    BEGINSELEN DER SCHEIKUNDE. (1900)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 22 (1900), S. 235-235 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja02042a024
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  • 4
    Electronic Resource
    Electronic Resource
    Tricyclic amides: a new class of systemic fungicides active against rice blast disease (1981)
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 29 (1981), S. 576-579 
    Details
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jf00105a036
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  • 5
    Electronic Resource
    Electronic Resource
    The Solubility of p-Terphenyl in o- and m-Terphenyls and in Biphenyl1 (1953)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 75 (1953), S. 436-442 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja01098a053
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  • 6
    Electronic Resource
    Electronic Resource
    Directional and compartmentalised drainage of interstitial fluid and cerebrospinal fluid from the rat brain (1992)
    Springer
    Acta neuropathologica 83 (1992), S. 233-239 
    Details
    ISSN: 1432-0533
    Keywords: Brain extracellular fluid ; Cerebrospinal fluid ; Perivascular cells ; Perivascular spaces ; lympharics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Pathways for drainage of interstitial fluid and cerebrospinal fluid from the rat brain were investigated by the injection of 2–5 μl Indian ink into cerebral white and grey matter and into the subarachnoid space over the vertex of the left frontal lobe. Animals were killed by formalin or glutaraldehyde perfusion 5 min-2 years after injection, and the distribution of ink over the surface of the brain, in 2-mm slices of brain cleared in cedar wood oil, in paraffin sections and by electron microscopy was documented. These investigations showed that carbon particles were distributed diffusely through the interstitial spaces of the white matter whereas they spread selectively along perivascular spaces in the grey matter outlining both arteries and veins and extending to surround capillaries within 1 h. Carbon particles were rapidly ingested by perivascular cells and, to some extent, by meningeal cells surrounding the larger vessels. Very little movement of carbon-labelled perivascular cells and perivascular macrophages was seen after 2 years. Carbon particles entering the subarachnoid space over the vertex of the cerebral hemispheres drained along selected paravascular and subfrontal pathways in the subarachnoid space to the cribriform plate and thence into nasal lymphatics and cervical lymph nodes. These studies demonstrate the diffuse spread of fluidborne tracers through cerebral white matter in the rat, the perivascular spread of tracer in grey matter and the compartmentalised directional flow or tracer through the subarachnoid space to the cribriform plate and nasal lymphatics. Furthermore, particulate matter selectively injected into perivascular spaces in rat grey matter is rapidly and efficiently ingested by perivascular cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00296784
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  • 7
    Electronic Resource
    Electronic Resource
    Assessment of Critical Closing Pressure in the Cerebral Circulation as a Measure of Cerebrovascular Tone (1999)
    Springer
    Acta neurochirurgica 141 (1999), S. 1221-1227 
    Details
    ISSN: 0942-0940
    Keywords: Keywords: Intracranial pressure; critical closing pressure; cerebrovascular tone; experiment; animal.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary ¶ Critical closing pressure (CCP) calculated from the blood flow velocity (FV) and arterial blood pressure (ABP) waveforms has been previously reported to be useful in the assessment of the dynamics of cerebral circulation. We investigated the relationship between CCP and intracranial pressure (ICP) and cerebrovascular tone in a model of intracranial hypertension in 22 anaesthetised New Zealand White rabbits during manipulations of arterial CO2, ABP and vasodilatation caused by hypoxia. Recordings were made of FV in the basilar artery, ABP and ICP during subarachnoid infusion of saline. During infusion ICP and CCP were significantly correlated (R=0.68; p〈0.001), but the magnitude of increase in ICP and CCP during infusion were not correlated to each other. Linear regression between the difference: CCP-ICP (representing a factor due to vasogenic tone) and cerebral perfusion pressure (CPP=ABP-ICP) was highly significant (R=−0.87; p〈0.01). Generally, CCP decreased significantly (p〈0.05) with hypercarbia, arterial hypotension and after and post-hypoxia and the difference: CCP-ICP decreased consistently after each vasodilatatory manoeuvre studied.  Our data confirmed the linear relationship between CCP and ICP, and between the difference: CCP-ICP and cerebrovascular tone. However, because the magnitude of increase in ICP was not correlated to magnitude of change in CCP, CCP cannot be use for detection of increasing ICP quantitatively.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007010050422
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  • 8
    Electronic Resource
    Electronic Resource
    Changes in transcranial Doppler flow velocity waveform following inhibition of nitric oxide synthesis (1997)
    Springer
    Acta neurochirurgica 139 (1997), S. 63-70 
    Details
    ISSN: 0942-0940
    Keywords: Transcranial Doppler ; cerebrocortical microcirculation ; basilar artery ; nitric oxide ; rabbits
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Background Analysis of the transcranial Doppler blood flow velocity (FV) waveform is used clinically to detect changes in cerebral haemodynamic profile. Such changes may be initiated both by alterations in microvascular resistance and in the tone of the cerebral arteries. Methods The role of endothelial mechanisms was investigated using inhibition of NO synthesis by systemic administration of NG-nitro-L-arginine methyl ester (L-NAME, 6 mg/kg) followed by simultaneous monitoring of both basilar artery FV and cerebrocortical microcirculation (laser Doppler flowmetry, LDF) in aneasthetised, ventilated rabbits over 60 minutes. Results Arterial blood pressure (AP) increased significantly (p 〈 0.01) above baseline level in the second minute following L-NAME and remained elevated until the end of experiment. Time average mean and systolic FV decreased immediately following L-NAME injection, with the statistically significant (p 〈 0.01) decrease from the third minute. Diastolic FV did not show such radical changes. LDF exhibited a slow decrease with time becoming significantly lower than baseline (p 〈 0.01) at 50 min. Conclusion A gradual decrease in cortical microcirculation preceded by a rapid reaction recorded in the TCD waveform implies that an increase in the tone of the great cerebral arteries is the predominant phenomenon seen during the acute phase of NO synthase inhibition.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01850870
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  • 9
    Electronic Resource
    Electronic Resource
    Quinacillin: A New Penicillin With Unusual Properties (1963)
    [s.l.] : Nature Publishing Group
    Nature 199 (1963), S. 354-356 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] A CYLATION of 6-aminopenicillanic acid (6-APA)1JL has provided a number of clinically effective, semi-synthetic penicillins2 some of which are resistant to hydrolysis by staphylococcal penicillinase. In the course of a programme concerned mainly with heterocyclic side-chain penicillins, we noted at ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/199354a0
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  • 10
    Electronic Resource
    Electronic Resource
    Iodination of Keratin (1953)
    [s.l.] : Nature Publishing Group
    Nature 171 (1953), S. 751-751 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The tyrosine contents of the treated and untreated wools were determined by the method of Block and Boiling1, and were found to be 0-214 and 4-77 per cent, respectively. If 3 : 5-di-iodo-tyrosine is the only reaction product, the fall in tyrosine content corresponds almost exactly to the amount of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/171751a0
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