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  • 1
    Electronic Resource
    Electronic Resource
    Multinuclear magnetic resonance studies of macrocyclic complexation in room-temperature molten salts (1984)
    s.l. : American Chemical Society
    Inorganic chemistry 23 (1984), S. 2557-2558 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic00185a001
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  • 2
    Electronic Resource
    Electronic Resource
    NMR and potentiometric studies of lithium salts in 1-butylpyridinium chloride-aluminum(III) chloride molten systems (1986)
    s.l. : American Chemical Society
    Inorganic chemistry 25 (1986), S. 4430-4433 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic00244a029
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  • 3
    Electronic Resource
    Electronic Resource
    Crystal and molecular structure of a lithium-C222B cryptate complex isolated from N-butylpyridinium chloride-aluminum(III) chloride molten salt medium (1986)
    s.l. : American Chemical Society
    Inorganic chemistry 25 (1986), S. 2825-2827 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic00236a033
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  • 4
    Electronic Resource
    Electronic Resource
    Intracellular elemental concentrations in renal tubular cells. An electron microprobe analysis (1979)
    Springer
    Journal of molecular medicine 57 (1979), S. 993-999 
    Details
    ISSN: 1432-1440
    Keywords: Electron microprobe analysis ; Intracellular electrolytes ; Kidney ; Ischaemia ; Elektronenstrahl-Mikroanalyse ; Intrazelluläre Elektrolyte ; Niere ; Ischämie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In order to be able to examine the processes involved in transepithelial transport in tissues, which are not composed of a single cell type, methods are required, which permit analysis at a cellular level. The technique of electron microprobe analysis permits the intracellular concentrations of many elements to be determined simultaneously in various portions of the cell. The application of this method to renal cortical tissue has shown that the best estimates of the cytoplasmic concentrations are to be obtained in regions close to the nucleus, farthest from the basolateral infoldings and microvilli, which separate the intracellular environment from the extracellular space. The nuclear concentrations of Na and K do not differ from those in the surrounding cytoplasm, although those of P and C1 are somewhat higher in cytoplasm. The intracellular element concentrations in the different cell types vary somewhat, proximal tubular cells contain higher concentrations of Na and C1 and lower ones of P than distal tubular cells. Following ischaemia, a manoeuvre know to result in a disturbance of intracellular electrolytes, Na was observed to rise and K to fall only in the non-surface cells of kidneys exposed to the air, but in all cells, if the kidneys were kept air-free in an atmosphere of N2. The proximal and distal tubular cells showed a variable resistance to ischaemia, the distal tubular cells being much more resistant. Despite the severity of the electrolyte disturbance following ischaemia, the intracellular composition was completely restored one hour after re-introducing renal blood flow.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01479984
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  • 5
    Electronic Resource
    Electronic Resource
    Short-term bromide uptake in skins of Rana pipiens (1994)
    Springer
    The journal of membrane biology 138 (1994), S. 171-179 
    Details
    ISSN: 1432-1424
    Keywords: Intracellular ions ; X-ray microanalysis ; Sodium ; Chloride ; Bromide ; Frog skin epithelium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Intracellular ion concentrations were determined in split skins of Rana pipiens using the technique of electron microprobe analysis. Based on the 1 min Br uptake from the apical bath, two types of mitochondria-rich (MR) cells could be distinguished: active cells which rapidly exchanged their anions with the apical bath and inactive cells which did not. Br uptake and frequency of active MR cells were closely correlated with the skin conductance, g t. Replacing Cl in the apical bath with an impermeant anion significantly lowered g t and the Br uptake and Na concentration of active cells. Even larger reductions were observed after apical amiloride (0.1 mm). The inhibition of the Br uptake was reversible by voltage clamping (100 mV, inside positive). Cl removal and amiloride also led to some shrinkage of active cells. The results suggest that the active cell is responsible for a large part of g t. Inactive MR cells had much lower Br and Na concentrations which were not significantly affected by Cl removal, amiloride, or voltage clamping. Principal cells, which represent the main cell type of the epithelium, showed only a minimal Br uptake from the apical side which was not correlated with g t. Moreover, Cl removal had no effect on the Na, Br, and Cl concentrations of principal cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00232645
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  • 6
    Electronic Resource
    Electronic Resource
    Electron microprobe analysis of intracellular electrolytes in resting and isoproterenol-stimulated exocrine glands of frog skin (1985)
    Springer
    The journal of membrane biology 86 (1985), S. 211-220 
    Details
    ISSN: 1432-1424
    Keywords: exocrine glands ; ion secretion ; electron microprobe analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary In the intact, in vitro frog skin, isoproterenol (ISO) stimulates and amiloride-insensitive increase in short-circuit current (SCC) that can be localized to the exocrine glands and is associated with secretion of chloride. To determine which cells in the glands respond to stimulation we measured the intracellular electrolyte concentrations of the various cell types of the mucous and seromucous glands of the skin using freeze-dried cryosections and electron microprobe analysis. In the resting state, the various cell types of the glands have intracellular electrolyte concentrations similar to the epithelial cells of the skin. Exposure to amiloride (10−4 m) has little effect on the concentration of Na and Cl in the cells of the glands. The effect of isoproterenol has two distinct phases. Analysis of glands in tissues frozen at the peak of the SCC response (13 min after addition of isoproterenol) shows that the only significant change is an increase in Na and Ca in a group of cells at the ductal pole of the acini of both gland types. These are termed “gland” cells. The duct cells and cells that secrete macromolecules did not show any significant changes at this timepoint. In the gland cells, after a one-hour exposure to isoproterenol the Na concentration is at prestimulation levels while Cl drops. There is also a smaller drop in Cl in the duct and skin epithelial cells. Ouabain, which can completely block the isoproterenol SCC response, has little short-term effect on Na and Cl in the control gland but accentuates the gain of Na and drop in Cl in the isoproterenol-treated condition. Bumetanide and, to a lesser extent, furosemide, also blocks the isoproterenol SCC response and causes a further drop in Cl. The results provide indirect evidence that a major portion of the ionic component of the gland secretion is produced by a distinct group of cells separate from those producing the macromolecular component and that the mechanism of secretion involves a Na:Cl coupled transport system linked to the activity of the basolateral Na pump.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01870600
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  • 7
    Electronic Resource
    Electronic Resource
    Formation of large unilamellar vesicles using alkyl maltoside detergents
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Biomembranes 862 (1986), S. 294-302 
    Details
    ISSN: 0005-2736
    Keywords: Alkyl maltoside ; Dialysis kinetics ; Vesicle formation
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2736(86)90231-2
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  • 8
    Electronic Resource
    Electronic Resource
    Preparation of biological soft tissue for electron microprobe analysis of electrolytes
    Amsterdam : Elsevier
    Cryobiology 11 (1974), S. 563 
    Details
    ISSN: 0011-2240
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0011-2240(74)90203-X
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  • 9
    Electronic Resource
    Electronic Resource
    EFFECTS OF MULTIPLE ADMINISTRATIONS OF THE MMPI FOR EMPLOYEE SCREENING (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Personnel psychology 47 (1994), S. 0 
    Details
    ISSN: 1744-6570
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Psychology
    Notes: Psychological screening has become commonplace in a number of occupational groups. With the growing popularity of screening and the relative scarcity of appropriate personality measures, re-screening individuals with the same inventory is frequent. This paper examines the effect of re-screening with the Minnesota Multiphasic Personality Inventory (MMPI) on contract workers (n = 1,997) from the nuclear power industry. Participants completed the Inventory as a part of a routine screening procedure. Each participant provided several profiles as a result of regular employment cycles. Although the differences are generally small, some scales show large enough mean changes to warrant concern when interpreting the profiles of those who have taken the profile multiple times. Although scale reliabilities tend to increase, the usefulness of the Inventory appears to decrease with an increasing number of administrations. The effect is one of increasing normality of test profiles. One interpretation of the results is that candidates for jobs become “test-wise,” and the scores are the result of a combination of responses to the repeated assessment. It becomes increasingly difficult to identify unfit employees with the Inventory. Given these results, further research on retesting effects of the Inventov, as well as other personality measures, is indicated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1744-6570.1994.tb01738.x
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  • 10
    Electronic Resource
    Electronic Resource
    Adenosine Inhibits Choline Kinase Activity and Decreases the Phosphorylation of Choline in Striatal Synaptosomes (1988)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 50 (1988), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: The main objective of these studies was to determine whether adenosine inhibits choline kinase in rat striata, leading to a decreased incorporation of choline into phosphorylcholine, a mechanism that may mediate seizure-induced increases in the levels of free choline in brain. Incubation of paniculate and soluble fractions of striatal synaptosomes with adenosine or its metabolically stable analogues significantly inhibited enzyme activity. The inhibition was noncompetitive versus choline and competitive versus MgATP. Inhibitor constants for adenosine, 2-chloroadenosine, and 2′,5′-dideoxyadenosine at the MgATP site were 94, 49, and 207 μM, respectively; these values were less than the Michaelis constant for MgATP (340 μM). To determine whether adenosine altered the phosphorylation of choline in an intact preparation, synaptosomes were in cubated with [3H]choline in the presence or absence of adenosine or its analogues and the amount of [3H]-phosphorylcholine formed from the [3H]choline taken up was measured. All compounds tested significantly reduced the synthesis of [3H]phosphorylcholine. Results suggest that following seizures or hypoxia, when levels of adenosine increase and the concentration of ATP decreases, inhibition of choline phosphorylation may be manifest, resulting in increased levels of free choline in brain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1988.tb02501.x
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