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  • 1
    Electronic Resource
    Electronic Resource
    Latex as a sunscreen carrier in a silicone vehicle (2002)
    Oxford, UK : Blackwell Science, Ltd
    International journal of cosmetic science 24 (2002), S. 0 
    Details
    ISSN: 1468-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This work comprises a study of the adsorption–desorption of three chemical sunscreens on the polymer surface of the latex Aquacoat, which has a high specific surface. The aim was to delay the release of these filters from the silicone excipient containing them and therefore increasing the substantivity, i.e. prolonging the sunscreening effect.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1467-2494.2002.00144.x
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  • 2
    Electronic Resource
    Electronic Resource
    Effect of chronic gestational treatment with caffeine or theophylline on Group I metabotropic glutamate receptors in maternal and fetal brain (2005)
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 94 (2005), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Pregnant rats were treated throughout the gestational period with either caffeine or theophylline, and its effect on the metabotropic glutamate receptor (mGluRs) signal transduction pathway was studied in both maternal and fetal brain. In maternal brain, radioligand binding assays showed that chronic treatment with methylxanthines caused a significant decrease in the total number of mGluRs. This decrease was accompanied by an increase in receptor affinity. Immunodetection showed that mGluR1a and phospholipase C β1 (PLCβ1) were significantly decreased in response to chronic methylxanthine treatment, whereas αGq/11 was not affected. A loss was also detected of PLC stimulation mediated by (S)-3,5-dihydroxyphenylglycine (DHPG), a selective Group I mGluR agonist, suggesting desensitization of the mGluR/PLC pathway. In fetal brain, a loss in total mGluRs was observed in fetuses from mothers treated with caffeine or theophylline, without variation in receptor affinity. A decrease in mGluR1a, αGq/11 and PLCβ1 levels was also observed in response to treatment. However, changes detected in this immature tissue were not associated with variations in PLC activity. These results suggest that chronic caffeine or theophylline treatment down-regulates several mGluR/PLC transduction pathway components in both maternal and fetal brain, causing a loss of receptor responsiveness only in maternal brain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.2005.03211.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Observation of light below Cerenkov threshold in a 1.5 meter long integrating Cerenkov counter (1983)
    Springer
    The European physical journal 18 (1983), S. 289-299 
    Details
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We have observed Cerenkov light, well below threshold, in an integrating Cerenkov counter used to determine particle composition of the secondary hadron beam, which is the source of Fermilab narrow-band neutrinos. The phenomenon can be understood in terms of diffraction effects in a finite length counter caused by radiation emitted by particles traversing the counter even when it is evacuated. At zero pressure, the light can be considered as transition radiation produced when particles enter and leave the counter. A standard Cerenkov diffraction formula describes both the normal Cerenkov radiation and the light emitted below Cerenkov threshold.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01573729
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  • 4
    Electronic Resource
    Electronic Resource
    On the role of glucose in capacitation and acrosomal reaction of guinea pig sperm (1983)
    New York, NY : Wiley-Blackwell
    Gamete Research 8 (1983), S. 335-344 
    Details
    ISSN: 0148-7280
    Keywords: guinea pig spermatozoa ; glucose ; glucose-6-P ; capacitation ; acrosomal reaction ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: In order to determine whether metabolizable sugars delayed capacitation of guinea pig spermatozoa, these cells were pre-incubated in Tyrode's pyruvate lactate glucose medium (T-PLG) or Tyrode's glucose solution (T-G). They were then transferred to minimal culture medium containing pyruvate and lactate (MCM-PL) and the occurrence of acrosomal reactions (AR) was determined by light microscopic observations of wet mount aliquots. The percentage of acrosomal reactions was quantitated in fixed samples and occurrence of a true AR was confirmed by electron microscopy. Activated acrosome-reacted spermatozoa were observed within 5 min when cells were transferred to MCM-PL solution, after preincubating them for 60-120 min either in T-PLG or T-G media. By 15 min in MCM-PL the percentage of acrosome-reacted spermatozoa reached values similar to those obtained in cells pre-incubated from the beginning in MCM-PL medium (P 〉 0.05 in both) but significantly different from T-PLG and T-G controls (P 〈 0.0005 in both). The acrosomal reaction was external calcium dependent and independent of the Tyrode's media pH ranging from 7.2 to 8.0. The results obtained suggested that capacitation occurred in T-PLG and that it was not delayed by glucose; the results also suggested that capacitation could occur within a short time with glucose as the only exogenous substrate, but that the acrosome reaction could have been arrested by a glucose metabolite. Data are presented which suggest that intracellular levels of glucose-6-phosphate (as 2-deoxyglucose-6-phosphate)could play a key role in the expression of the acrosome reaction in sperm already able to perform it. A new hypothesis is suggested for the development of the fertilizing potential of guinea pig sperm when in the female genital tract.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrd.1120080404
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    Paper (German National Licenses)
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