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  • 1
    Electronic Resource
    Electronic Resource
    The prevalence of diet-induced migraine (1984)
    USA/Oxford, UK : Blackwell Science Ltd
    Cephalalgia 4 (1984), S. 0 
    Details
    ISSN: 1468-2982
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Nineteen percent of about 490 patients with classical or common migraine reported that headaches can be precipitated by chocolate, 18% by cheese and 11% by citrus fruit. and a highly significant majority of these patients were sensitive to all three foods. Twenty-nine percent of the patients reported sensitivity to alcohol; again this was significantly associated with sensitivity to the three food stuffs, though a substantial number of patients were sensitive to alcohol but not foods. Thirty-one percent of 331 female patients believed that oral contraceptives precipitated headaches, but this could not be related to any dietary response. Patients with affected relatives were significantly more likely to report sensitivity to alcohol and chocolate; sensitivity to cheese and citrus fruit was less strongly related, and there was no relationship at all for oral contraceptives. These correlations suggest that food induced headaches are mediated by chemical constituents common to these foods.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1468-2982.1984.0403179.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Chocolate is a migraine-provoking agent (1991)
    USA/Oxford, UK : Blackwell Science Ltd
    Cephalalgia 11 (1991), S. 0 
    Details
    ISSN: 1468-2982
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Patients with migraine who believed that chocolate could provoke their attacks were challenged with either chocolate or a closely matching placebo. In a double-blind parallel group study, chocolate ingestion was followed by a typical migraine episode in 5 out of 12 patients, while none of the 8 patients challenged with placebo had an attack (p = 0.051). The median time to the onset of the attack was 22 h. This brief study provides some objective evidence that chocolate is able to provoke a migraine attack in certain patients who believe themselves sensitive to it.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1468-2982.1991.1102093.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Kinetics of platelet 5-hydroxytryptamine uptake in headache patients (1991)
    USA/Oxford, UK : Blackwell Science Ltd
    Cephalalgia 11 (1991), S. 0 
    Details
    ISSN: 1468-2982
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Platelet 5-hydroxytryptamine (5-HT) uptake was measured in asymptomatic headache patients attending a specialist migraine clinic, and in hospital staff who did not suffer from regular or severe headache. Current levels of anxiety and depression were assessed in all subjects using the Hospital Anxiety and Depression (HAD) scale and their possible influence on the uptake kinetics taken into account during the analysis of results. The Michaelis-Menten constant (Km) was significantly raised in common migraine and tension headache compared with controls (p 〈 0.001 and p 〈 0.01, respectively), but not in classical migraine or cluster headache. The increase remained significant after adjusting for differences in age, sex, presence of anxiety or depression (HAD sub-scale score 3; 8), drug intake during the week before testing, time elapsed since last attack and time of assay (am or pm). No differences were observed between patients and controls in the maximal rate of uptake (Vmax) or platelet count, and previous reports of a reduction in Vmax in patients experiencing attack within 5 days prior to testing could not be confirmed. The cause and significance of an increased Km are not clear, but plasma factors acting as competitive inhibitors for the uptake site or an alteration in the configuration of the uptake site are possible explanations. If confirmed, the shared biochemical abnormality may suggest that common migraine and tension headache have a common pathogenesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1468-2982.1991.1103141.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Migraine to the year 2000 (1995)
    USA/Oxford, UK : Blackwell Science Ltd
    Cephalalgia 15 (1995), S. 0 
    Details
    ISSN: 1468-2982
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Although migraine is inextricably bound up with 5-hydroxytryptamine and its many receptors, its precise mechanisms continue to elude us and there is still no clear evidence supporting either a vascular or neurogenic hypothesis unequivocally. What appears to distinguish migraine sufferers from normal subjects may be a greater genetic sensitivity to a wide variety of triggering agents-even including nitric oxide and the migraine aura, as well as those more usually recognized. Attention is drawn to a possible role for neurotrophins, such as the hyperalgesia-provoking nerve growth factor (NGF) in particular, as well as basic fibroblast growth factor (bFGF) and brain-derived neurotrophic factor (BDNF).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1468-2982.1995.1504259.x
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Red wine-induced release of [14C]5-hydroxytryptamine from platelets of migraine patients and controls (1996)
    USA/Oxford, UK : Blackwell Science Ltd
    Cephalalgia 16 (1996), S. 0 
    Details
    ISSN: 1468-2982
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Red wine-induced release of [14C]5-hydroxytryptamine (5HT) from platelets of red wine-sensitive migraine patients, migraine patients not sensitive to red wine and controls, was determined in vitro. No significant differences in platelet [14C]5HT release were found between any of the groups investigated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1468-2982.1996.1601041.x
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Dietary migraine: recent progress in the red (and white) wine story (1995)
    USA/Oxford, UK : American Association for the Study of Headache/Blackwell Science Ltd
    Cephalalgia 15 (1995), S. 0 
    Details
    ISSN: 1468-2982
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The concept of dietary migraine as a clinical entity remains controversial. We review here such objective evidence that has been put forward for its existence. Red wine, in particular, is commonly alleged to initiate attacks in susceptible individuals. We discuss how some of its recently described pharmacological properties might trigger off the sequence of events leading to migrainous headache.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1468-2982.1995.015002101.x
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Inhibition of 5-Hydroxytryptophan Decarboxylase by Phenylalanine Metabolites (1958)
    [s.l.] : Nature Publishing Group
    Nature 181 (1958), S. 186-187 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Table l. INHIBITION OF S-HYDROXYTBYPTOPHAN DEOARBOXYLASE BY PHENYLALANINE METABOLITES Inhibition of Cone. dihydroxy- Additions (pinoles/ 3ml.) Ad.CO,/ 40 min. Inhibition (per cent) phenylalanine decarboxylase* (per cent) Control _ 75-7 _ _ Phenylpyruvic 100 15-7 79-3 100 ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/181186b0
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Effect of Urinary p H on 5-Hydroxytryptamine Excretion in the Rat (1961)
    [s.l.] : Nature Publishing Group
    Nature 189 (1961), S. 838-840 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Table l. SHOWING UEINAKY EXCRETION OF S-HYDROXYTRYPTAMINB AND S-HYDROXYINDOLBACBTIC ACID AS PERCENTAGE OF DOSE OF L-"C-5-HYDROXYTRYPTOPHAN OR 14C-5-HYDROXYTRYPTAMINE IN 'ACID* OR 'ALKALINE* RATS DL-14C-5-Hydroxytryptophan administration Hr. of exp. Exp. 1 Exp. 2 Ex p. 3 Exp. 4 ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/189838a0
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    Transmission of Noradrenaline across the Human Placenta (1963)
    [s.l.] : Nature Publishing Group
    Nature 197 (1963), S. 598-598 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] It seemed important to try to elucidate this point. Although the administration of radioisotopically labelled noradrenaline to the mother followed by direct detection of activity in the foetal blood appeared to offer the best chance of obtaining this information, it was not considered justifiable ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/197598a0
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Estimation of homovanillic acid in urine
    Amsterdam : Elsevier
    Analytical Biochemistry 8 (1964), S. 282-292 
    Details
    ISSN: 0003-2697
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0003-2697(64)90059-4
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    Paper (German National Licenses)
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