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  • 1
    Electronic Resource
    Electronic Resource
    Effects of continuous light on rat parotid gland structure and reactivity (1989)
    Springer
    Anatomy and embryology 179 (1989), S. 497-501 
    Details
    ISSN: 1432-0568
    Keywords: Parotid gland ; Ultrastructure ; Amylase ; Secretion ; Isoproterenol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effects of continuous light on ultrastructural organization and sympathetic secretory responses of the rat parotid gland are reported. After 50 days of continuous light exposure, the fine structure of the parotid gland exhibited features of enhanced secretory activity as judged by the striking development of rough endoplasmic reticulum and Golgi complexes, the depletion of secretory granules and the increased turnover of secretory cells. The secretory responses of parotid gland to isoproterenol revealed that continuous light induced a 30% increase in amylase release. This secretory hyperactivity appears to be related to a postsynaptic supersensitivity of sympathetic fibers of the autonomic nervous system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00319593
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  • 2
    Electronic Resource
    Electronic Resource
    Drug utilization by children in Tenerife Island (1988)
    Springer
    European journal of clinical pharmacology 34 (1988), S. 495-499 
    Details
    ISSN: 1432-1041
    Keywords: drug utilization ; drug surveillance ; drug monitoring ; Tenerife (Canary Islands) ; children ; childhood diseases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Drug utilization was studied in children below 14 years of age in Tenerife, Canary Islands, who were seen as outpatients by 15 paediatricians and 10 general practitioners. Data on diagnosis, previous drug exposure and prescriptions were collected from a random sample of 1327 children. Nose and throat infections (40.1%), respiratory diseases (10.2%) and miscellaneous symptoms, namely common cold, influenza or nasal congestion (10.5%), were the most frequent reasons for visiting a physician. Antibiotics represented 28.5% of the prescriptions. The youngest group (0–2 years) received more drugs than the other two groups (2–6 and 6–14 years), and 8.4% of the children did not receive any drug. Only 358 (5.1%) of the 7,000 pharmaceutical specialities available were used, and the 10 most frequently prescribed drug products constituted more than 30% of all prescriptions. Combination drugs accounted for 42.4% of the prescribed items. Healthy children presenting only for check up were frequently treated with drugs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01046708
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  • 3
    Electronic Resource
    Electronic Resource
    Paediatric drug prescribing. A comparison of Tenerife (Canary Islands, Spain) and Sweden (1989)
    Springer
    European journal of clinical pharmacology 37 (1989), S. 65-68 
    Details
    ISSN: 1432-1041
    Keywords: drug utilization ; antibiotics ; paediatric prescribing ; childhood ; Swedish Diagnosis and Therapy Survey ; international comparison ; therapeutic traditions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The prescribing of medicines for ambulant children below 14 years of age has been compared between Tenerife (Spain) and Sweden. Data obtained from a random sample of 1327 children in a prospective study in Tenerife were compared with data from 3901 children in a Swedish survey linking diagnosis and therapy. Upper respiratory tract infection was the main diagnosis in both countries and antibiotics was the most frequently prescribed drug group (28.2% in Tenerife and 28.8% in Sweden). Half of the children in Sweden did not receive any medication, but only 10% of those in Tenerife did not receive a prescription. Children who received a prescription on average got 1.4 drugs in Sweden and 2.3 in Spain. Amongst the ten most commonly prescribed products in Sweden there were 11 active pharmacological principles as compared to 25 in Spain. These most frequently used preparations accounted for two thirds of all the prescriptions for children in Sweden and one third in Tenerife. In conclusion, drugs were significantly more often used to treat paediatric outpatients in Tenerife than in Sweden. The prescribing physician in Spain also chose a wider variety of drugs and more commonly used fixed combination products.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00609427
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  • 4
    Electronic Resource
    Electronic Resource
    The virial coefficients of the pearl-necklace model (2000)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 113 (2000), S. 10398-10409 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: We consider the virial coefficients of an idealized model polymer under good solvent conditions, the so-called pearl-necklace model, consisting of a fully flexible chain of m tangent hard spheres. We employ an efficient algorithm recently proposed to determine the second, third, and fourth virial coefficients of chains of up to 100 monomers. We also include some preliminary results for chains of up to 200 monomers. These results, which include the first off-lattice calculations of third and fourth virial coefficients of polymer models, are compared with predictions obtained from Wertheim's equation of state. It is shown that, despite the good agreement of Wertheim's equation of state for the compressibility factor, the predictions for the individual virial coefficients are far from satisfactory. It it shown that for the values of m considered in this work, the truncated virial expansion correctly describes the equation of state up to packing fractions of 0.25. A new equation of state which describes the low and high density regimes of the pearl-necklace model is proposed. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1322637
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  • 5
    Electronic Resource
    Electronic Resource
    Effects of BN 52021 on hemodynamics on rats with experimental cirrhosis of the liver
    Amsterdam : Elsevier
    Prostaglandins 30 (1985), S. 717 
    Details
    ISSN: 0090-6980
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0090-6980(85)90061-9
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  • 6
    Electronic Resource
    Electronic Resource
    Host range of Acremonium cucurbitacearum, cause of Acremonium collapse of muskmelon (1998)
    Oxford, U.K. and Cambridge, USA : Blackwell Publishers
    Plant pathology 47 (1998), S. 0 
    Details
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: The pathogenicity of Acremonium cucurbitacearum to 31 cucurbits, 18 crop plant species, and 15 weed species was evaluated under greenhouse conditions. This study demonstrates that many other cucurbits in addition to muskmelon and watermelon can potentially serve as hosts of A. cucurbitacearum. Using a disease severity index (DSI), all muskmelon and watermelon cultivars were ranked as susceptible or highly susceptible, with the exception of honeydew cultivar TAM Dew Improved, which ranked resistant in one study. Highly resistant cucurbits included Cucurbita maxima (autumn squash), Luffa acutangula, L. aegyptiaca (sponge gourd) and Benincasa hispida (ash gourd). Cyclanthera pedata and Cucumis miriocarpus were rated as resistant. The percentage recovery of A. cucurbitacearum ranged from 8% to 100% and tended to be higher in plants with a higher DSI. Other crops and weed species common to muskmelon production fields are not likely to be involved in the perpetuation or propagation of the fungus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3059.1998.00199.x
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  • 7
    Electronic Resource
    Electronic Resource
    Utility of bibliometric analysis for research policy: A case study of Spanish research in neuroscience
    Amsterdam : Elsevier
    Research Policy 19 (1990), S. 457-466 
    Details
    ISSN: 0048-7333
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Economics , Nature of Science, Research, Systems of Higher Education, Museum Science
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0048-7333(90)90053-9
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  • 8
    Electronic Resource
    Electronic Resource
    Effect of sexual steroids upon ontogeny of alpha-amylase of rat parotid gland (1982)
    Springer
    Molecular and cellular biochemistry 44 (1982), S. 65-69 
    Details
    ISSN: 1573-4919
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Summary The effect of gonadectomy (at the 10th day of life) and treatment with sexual steroids (during the first month) upon development of alpha-amylase activity in rat parotid gland has been studied. Alpha-amylase specific activity of parotid glands from 20-day-old orchidectomized rats and from 25-day-old ovariectomized animals was significantly higher than that of intact male and female rats of the same age respectively. Spayed males treated with testosterone (10 μg/day on the 13th, 15th, and 17th day) and ovariectomized rats treated with oestradiol (2.5 μg/day from the 16th to the 22nd day) showed values of enzymic activity similar to those of normal animals. Results indicate that oestradiol and testosterone have an inhibitory effect upon the increase of alpha-amylase activity in parotid gland during a very defined period of development.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00226891
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  • 9
    Electronic Resource
    Electronic Resource
    Metabolic changes induced by galactose (1975)
    Springer
    Cellular and molecular life sciences 31 (1975), S. 153-154 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Resumen La administracion de 100 g de galactosa a 9 voluntarios sanos por via oral, demostro ser capaz de elevar la insulinemia, sin modificar la glucosa en sangre. Secundariamente se aprecio un descenso de los acidos grasos libres. La galactosa puede actuar directamente sobre el pancreas o a traves del intestino.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01990676
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  • 10
    Electronic Resource
    Electronic Resource
    Ontogenesis of alpha-amylase in rat parotid gland during postnatal development (1981)
    Springer
    Histochemistry and cell biology 71 (1981), S. 125-133 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Changes in α-amylase (α-1,4-glucan-4-glucanohydrolase, EC 3.2.1.1) of parotid gland were investigated during postnatal development of the rat. Modifications in amylase activity after birth allow the distinction of three stages which can be correlated with the morphologic development of the parotid gland. Significant sexual differences in the evolution of α-amylase activity were found. During the first stage (from birth to the 20th day) there is a higher increase in females, while males have a more pronounced increment in the second stage (from the 20th to the 30th day). By means of gel electrophoresis of parotid extracts, four molecular forms of amylase can be separated. The slowest migrating band (Form 1) is not detected at the initial stage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00592576
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