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  • 1
    ISSN: 1432-1068
    Keywords: Modular femoral prosthesis ; Fretting ; Taper socket ; Cementless
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les auteurs décrivent une nouvelle prothèse fémorale modulaire associant une prothèse conventionnelle et un clou centro-médullaire. La prothèse est constituée d’une pièce céphalique et d’une partie diaphysaire fixées ensemble par un cône morse. Chaque pièce est modulaire selon les besoins en longueur et en diamètre. L’antéversion de la pièce céphalique est libre. Les pièces diaphysaires ont une courbure sagittale anatomique et sont creuses, permettant l’utilisation d’un guide centro-médullaire. Les pièces diaphysaires longues peuvent être verrouillées. Les pièces céphalique et diaphysaire sont en alliage de titane et la pièce diaphysaire a une surface grenaillée dans sa partie proximale. Le cône morse a été optimisé par l’adjonction d’une rainure qui a diminué l’usure par abrasion lors des tests de fatigue. Aucun démontage de la jonction intraprothétique et aucune fracture dé tige n’a été rencontrée lors de c es tests. La technique opératoire n’offre aucune particularité. Cent vingtquatre prothèses ont été implantées depuis 1990, principalement pour des fractures du col fémoral et des changements de prothèses totales de hanche. Les résultats cliniques sont en cours d’investigation. D’autres indications plus rares ont été choisies : pseudarthrose per-trochantérienne, fracture sur coxarthrose, chirurgie métastatique. Cette prothèse permet un ancrage diaphysaire stable dans les pertes de substance de l’extrémité supérieure du fémur, et autorise ainsi la repousse osseuse dans cette zone, spontanée ou après greffe osseuse, et la fixation proximale secondaire. L’optimisation du cône morse a permis de diminuer de façon considérable l’usure par abrasion. La modularité de la prothèse permet de s’adapter à toutes les morphologies et toutes les situations cliniques.
    Notes: Summary The development and clinical indications of a new modular femoral endoprosthesis consisting of a head and shaft component is discribed. Components are available in different lengths and diameters and therefore can be joined individually depending on the patients anatomy and surgery required. Both parts are joined by a unique optimized taper socket with a groove, avoiding fretting and corosion. Fatigue tests showed no loosening of the tapered connection and no prosthesis fracture. The advantage of this new modular prosthesis is diaphyseal stabilization, if necessairy by two distal interlocking screwes. Indications are revisions, pertrochanteric femoral and neoplastic fractures if cementless bridging of boney defects in the calcar region must be achieved. Further indications are femoral neck fraktures and coxarthrosis if stable diaphyseal fixation is required. The material and surface structure as well as the philosophie of the distal fixation are discussed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of orthopaedic surgery & traumatology 4 (1994), S. 143-148 
    ISSN: 1432-1068
    Keywords: Ligament croisé antérieur ; Résultats cliniques ; Contrôle de qualité ; Mesure instrumentale de la laxité ; Evaluation isocinétique de la fonction musculaire ; Anterior cruciate ligament ; Clinical scores ; Quality control ; Instrumented laxity testing ; Isokinetic muscle force
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary An objective functional evaluation after acute repair of unilateral anterior cruciate ligament (ACL) rupture was performed in a homogeneous group of 37 patients at a mean of 44.4 months after trauma. A patient questionnaire, standardized clinical testing, instrumented laxity testing and concentric isokinetic muscle torque evaluation were included. Instrumented laxity testing proved to be closely correlated with the pivot shift test (r=0.54, p〈0.001) and the Lachman test (r=0.73, p〈0.001), but offered a far better resolution. The degree of anterior instability as measured could be shown to correlate negatively with the isokinetic flexor muscle torque (r=−0.61, p〈0.001) and the hamstring/quadriceps ratio (r=−0.44, p〈0.05). The intraindividual differences of instrumented laxity testing revealed that a significant degree of instability (〉2 mm) was present in 49% of the patients contrasting with the good result in the Lysholm score (mean=84.5 pts.) and a 74% rate of satisfied patients. Instrumented laxity testing makes a significant contribution to objective evaluation of functional results after ACL repair.
    Notes: Résumé Une évaluation fonctionnelle objective a été effectuée après réparation unilatérale de rupture du ligament croisé antéro-externe (LCAE) dans une série homogène de 37 patients, avec un recul moyen de 44,4 mois par rapport au traumatisme. Un questionnaire, un contrôle clinique standardisé, des tests instrumentaux de laxité ligamentaire ainsi qu'une évaluation du moment de torsion musculaire isokinétique concentrique furent utilisés. Le contrôle instrumental de la laxité ligamentaire peut être considéré comme très proche du test d'instabilité du pivot (r = 0,54, p 〈 0,001) et le signe de Lachman (r = 0,73, p 〈 0,001) mais est plus rapidement décisif. Le degré d'instabilité antérieure mesuré pourrait être considéré comme corrélé négativement avec le moment de torsion musculaire isokinétique concentrique (r = 0,61, p 〈 0,001) et le rapport ischio-jambiers/quadriceps (r = 0,44, p 〈 0,005). Les différences entre les sujets des tests instrumentaux de laxité ligamentaire révèlèrent qu'un degré significatif d'instabilité (〉 2 mm) existait chez 49 % des patients, ce qui contraste avec les bons résultats au score de Lysholm (moyenne : 84,5 points) et une proportion de 74 % de patients satisfaits. Ainsi le test instrumental de laxité ligamentaire apporte-t-il une contribution importante à l'évaluation fonctionnelle post-opératoire des ligamentoplasties du LCAE.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1076
    Keywords: Key words Homocystinuria ; Excitotoxicity ; Organotypic cultures ; Xenopus oocytes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The excitotoxic action of homocysteine and related sulphur-containing metabolites was investigated in organotpyic cultures derived from rat brain cortex and hippocampus by inhibition experiments using antagonists selective for different glutamate receptor subtypes. In addition the direct interaction of these metabolites with glutamate receptors expressed in frog oocytes was tested by conventional two electrode voltage clamp techniques. Conclusion Neurodegeneration and epilepsy observed in homocystinuria may be mediated by l-homocysteic and l-homocysteine sulphinic acid. Both metabolites exhibit excitotoxic potency by interaction with different glutamate receptor subtypes.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 71 (2000), S. 1319-1324 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: An experimental device is reported that utilizes time-correlated nanosecond light pulses in combination with photoionization mass spectrometry. A primary light pulse is generated by a tunable dye laser in the ultraviolet regime, which photolyzes neutral gas targets under collision free conditions. Subsequently, a time-correlated extreme ultraviolet-light pulse comes from a laser-produced plasma that is monochromatized in the 10–25 eV regime. The photolysis products are ionized by one-photon absorption, so that the cations are finally detected by time-of-flight mass spectrometry. The performance of this experimental approach is characterized by investigating the primary photolysis products of chlorine dioxide. Finally, possible applications of this approach are briefly discussed. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 50 (1994), S. 1252-1254 
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 50 (1994), S. 1710-1713 
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 53 (1997), S. 1383-1384 
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 54 (1998), S. 0-0 
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 49 (1993), S. 1066-1068 
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 54 (1998), S. 521-523 
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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