ISSN:
1432-0568
Keywords:
Juxtaglomerular apparatus
;
Extraglomerular mesangial cell field
;
Structure-function correlation
;
Resetting of tubuloglomerular feedback
;
Rat
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The extraglomerular mesangial cell field was studied by morphometric techniques in volume expanded and volume depleted rats. The volume density of the extraglomerular mesangial interstitium was found to be significantly different between the two conditions, 16.9±3.7% in volume depletion and 29.0±4.1% in volume expansion. No difference in the volume density of the peritubular interstitium could be detected under the same conditions. These findings are interpreted as indicating a specific sensitivity of the extraglomerular mesangial interstitium to changes in body fluid content, a phenomenon which may play a role in the mechanism of resetting the tubulo-glomerular feedback control.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00319007
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