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  • 1
    Electronic Resource
    Electronic Resource
    A temporary local extrinsic denervation facilitates the regeneration of the rat enteric nervous system after surgical interventions - postoperative outcome and morphological results
    Amsterdam : Elsevier
    Regulatory Peptides 40 (1992), S. 264 
    Details
    ISSN: 0167-0115
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0167-0115(92)90445-Z
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A temporary, local extrinsic denervation facilitates the regeneration of the rat enteric nervous system after surgical interventions - neuropeptide levels in submucosa and muscularis
    Amsterdam : Elsevier
    Regulatory Peptides 40 (1992), S. 263 
    Details
    ISSN: 0167-0115
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0167-0115(92)90444-Y
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Imaging of lung cancer with fluorine-18 fluorodeoxyglucose: comparison of a dual-head gamma camera in coincidence mode with a full-ring positron emission tomography system (1999)
    Springer
    European journal of nuclear medicine 26 (1999), S. 388-395 
    Details
    ISSN: 1619-7089
    Keywords: Key words: Positron emission tomography ; Dual-detector coincidence imaging ; Fluorodeoxyglucose ; Lung cancer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Dual-head gamma cameras operated in coincidence mode are a new approach for tumour imaging using fluorine-18 fluorodeoxyglucose (FDG). The aim of this study was to assess the diagnostic accuracy of such a camera system in comparison with a full-ring positron emission tomography (PET) system in patients with lung cancer. Twenty-seven patients (1 female, 26 males, age 62±9 years) with lung cancer or indeterminate pulmonary nodules were studied on the same day with a full-ring PET scanner (Siemens ECAT EXACT) and a coincidence gamma camera system (ADAC Vertex MCD). Sixty minutes after injection of 185–370 MBq FDG, a scan of the chest was performed with the full-ring system. Approximately 2 h p.i., the coincidence camera study was performed. Coincidence gamma camera (CGC) and PET images with (PETac) and without attenuation correction (PETnac) were analysed independently by two blinded observers. In addition, FDG uptake in primary tumours and involved lymph nodes was quantified relative to normal contralateral lung (T/L ratios). All primary tumours were histologically proven. The lymph node status was histologically determined in 23 patients. In four patients, no lymph node sampling was performed because of extensive disease or concurrent illnesses. In the 27 patients, 25 primary lung cancers and two metastatic lesions were histologically diagnosed. The number of coincidences per centimetre axial field of view was 3.33±0.93×105 for the CGC and 1.09±0.36×106 for the dedicated PET system. All primary tumours (size: 4.6±2.6 cm) were correctly identified in the CGC and dedicated PET studies. T/L ratios were 4.7±2.5 for CGC and 6.9±2.8 for PETnac (P 〈0.001). Histopathological evaluation revealed lymph node metastases in 11 of 88 sampled lymph node stations (size: 2.3±1.0 cm). All lymph node metastases were identified in the PETac studies, while PETnac detected 10/11 and CGC 8/11. For positive lymph nodes that were visible in CGC and PETnac studies, T/L ratios were 3.7±2.3 for CGC and 6.6±3.1 for PETnac (P=0.02). The diameters of false-negative lymph nodes in the CGC studies were 0.75, 1.5 and 2 cm. False-positive FDG uptake in lymph nodes was found in two patients with all three imaging methods. For all lesions combined, T/L ratios in CGC relative to PETnac studies decreased significantly with decreasing lesion size (r=0.62; P〈0.001). In conclusion, compared with a full-ring PET system the sensitivity of CGC imaging for detection of lung cancer is limited by a lower image contrast which deteriorates with decreasing lesion size. Nevertheless, the ability of CGC imaging to detect pulmonary lesions with a diameter of at least 2 cm appears to be similar to that of a full-ring system. Both systems provide a similar specificity for the evaluation of lymph node involvement.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002590050402
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Nahtfreie Anastomosen an der Ratte, am Kaninchen und am Schwein (1988)
    Springer
    Langenbeck's archives of surgery 373 (1988), S. 91-96 
    Details
    ISSN: 1435-2451
    Keywords: Intestinal anastomosis ; Sutureless anastomosis ; Breaking strength ; Bursting pressure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Am Rattencolon, Kaninchencolon und Schweinedünndarm konnte nachgewiesen werden, daß eine Heilung von Darmanastomosen möglich ist, obwohl die initial adaptierende Naht nach einer Stunde entfernt wird. Durch invertierende Einzelknopfnähte (Jobert) werden die Darmenden zunächst adaptiert. Nach einer Stunde ist eine fibrinöse Verlötung der Darmwände eingetreten. Die invertierten Serosaflächen sind verklebt. Der Berstungsdruck weist am 1., 3. und 7. postoperativen Tag zwischen nahtfreier und Nahtanastomose keinen signifikanten Unterschied auf. Die Reißfestigkeit der Anastomose beträgt eine Stunde nach Entfernung der Fäden 19,5 ± 5,8 g = 0,19 N und 24 h nach Entfernungder Fäden80.5 g ± 9,5 g = 0,80 N. Art und Ausdehnung der Verwachsungen sind bei nahtfreien und genähten Anastomosen gleich. Im histologischen Bild zeigen Nahtanastomosen Nekroseareale, welche bei nahtfreien Anastomosen fehlen.
    Notes: Summary Healing of intestinal anastomoses was found to be effective in rat, rabbit and pig even after temporary approximation by sutures for one hour. Approximation of bowel segments was achieved by interrupted inverting sutures. After one hour a fibrinous connection of inverted serosa segments was to be observed. Bursting pressure was determined on the 1st, 3rd and 7th postoperative day. There was no significant difference between sutureless and regular anastomoses. Determination of breaking strength of approximated anastomoses one hour and twenty-four hours after removal of sutures was found to be 0.19 N and 0.8 N, respectively. Extent of adhesions was similar in conventional and sutureless anastomoses. Histologic analyses revealed areas of necrosis in sutured anastomoses, whereas in sutureless anastomoses no necrosis could be detected.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01262770
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Untersuchung zur Frühphase der Anastomosenheilung unter besonderer Berücksichtigung von Peritonitis und Ischämie (1988)
    Springer
    Langenbeck's archives of surgery 373 (1988), S. 217-221 
    Details
    ISSN: 1435-2451
    Keywords: Sutureless anastomosis ; breaking strength ; Peritonitis ; Ischemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Als Parameter zur Messung der biomechanischen Festigkeit von nahtfreien Darmanastomosen innerhalb der ersten 24 postoperativen Stunden eignet sich am besten die Prüfung der Reißfestigkeit. Hierbei wird die Anastomose durch sechs, in Jobert-Technik angelegte Fäden adaptiert, die nach einer Stunde wieder entfernt werden. Diese kurze Adaptation reicht aus, da das ausgeschwitzte Fibrin die Anastomose schon nach einer Stunde fest zusammenhält. Unsere Messungen wurden an nahtfreien Anastomosen unter Normalbedingungen, Peritonitis, einseitiger und kompletter Ischämie durchgeführt. Zum Vergleich wurde auch die Reißfestigkeit der konventionell genähten Anastomosen in den ersten 24 postoperativen Stunden bestimmt. 1. Die nahtfreie Anastomose weist am ersten postoperativen Tag stets eine geringere Reißfestigkeit auf als die konventionell genähte. 2. Während nach 6 h die Reißfestigkeit unter Normalbedingungen stark ansteigt, bleibt sie unter Peritonitis unverändert auf niedrigem Niveau. 3. Unter absoluter Ischämie wird die nahtfreie Anastomose auch nach dreistündiger Fadenadaptation nach Ziehen der Fäden sofort insuffizient. Die Reißfestigkeit ist damit nicht meßbar. 4. Bei einseitiger Ischämie hält die Anastomose zwar nach Entfernen der Fäden, die Reißfestigkeit ist jedoch gegenüber der normalen nahtfreien Anastomose signifikant erniedrigt.
    Notes: Summary Experimental sutureless colonic anastomosis was evaluated under various conditions during the first 24 postoperative hours. Adaptation of large bowel segments was achieved by interrupted inverting sutures, which were removed after one hour. This short adaptation period was sufficient for fibrinous contact of bowel segments. Breaking strength of intestinal anastomosis was determined unter normal conditions, in peritonitis, complete ischemia and unilateral ischemia of one bowel segment. As control parameter breaking strength of conventional anastomosis was determined under normal conditions. We obtained the following results: 1) Sutureless anastomosis exhibited significantly lower breaking strength than conventional anastomosis. 2) Sutureless anastomosis showed a significant increase in breaking strength under normal conditions after the first 6 h, on the contrary breaking strength remained at lower levels in peritonitis. 3) In complete ischemia anastomotic failure was observed even after 3 h of adaptation. Therefore breaking strength was not measurable. 4) Under unilateral ischemia breaking strength of intestinal anastomosis was significantly lower than under normal conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01261812
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