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  • 1
    Electronic Resource
    Electronic Resource
    TRH-refraktäre TSH-Werte, Trijodthyroninspiegel und T3/T4-Quotienten bei mit T3/T4-Kombinationspräparaten behandelten hypothyreoten Kindern (1977)
    Springer
    Journal of molecular medicine 55 (1977), S. 131-135 
    Details
    ISSN: 1432-1440
    Keywords: Hypothyroidism ; Children ; T3/T4 preparations ; TRH-test ; Triiodothyrinine ; T3/T4 quotient ; Hypothyreose ; Kinder ; T3/T4-Kombinationspräparat ; TRH-Test ; Trijodthyronin ; T3/T4-Quotient
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei 23 Kindern mit primärer Hypothyreose, die mit Thyroxin (T4) und Trijodthyronin (T3) enthaltenden Kombinationspräparaten behandelt worden waren, wurden TRH-Teste, TBI, T3- und T4-Bestimmungen durchgeführt. Die T3/T4-Quotienten wurden berechnet. 7 von 10 Patienten mit TRH-refraktären TSH-Werten und normalen T4-Spiegeln wiesen überhöhte T3-Werte auf. Bei 6 von diesen Patienten konnten pathologisch überhöhte T3/T4-Quotienten beobachtet werden. Eine TRH-refraktäre TSH-Suppression wurde nur bei hohen T4-Werten gefunden. Nach einer Reduktion der Substitutionsdosis normalisierten sich die überhöhten T3-Spiegel. Die Befunde zeigen, daß nicht nur die T4-Werte sondern auch die TSH- und T3-Spiegeln unter der Behandlung mit Schilddrüsenhormonen kontrolliert werden sollten. Die Durchführung der Substitutionstherapie der Hypothyreose mit T3/T4-Kombinationspräparaten im Verhältnis 1:4 sollte überdacht werden.
    Notes: Summary TRH-tests, triiodothyronine (T3), TBI, and thyroxine (T4) determinations were carried out in 23 children with primary hypothyroidism treated with T3/T4-preparations. T3/T4 quotients were calculated. 7 out of 10 patients with TRH refractory TSH values and normal T4 levels had T3 values above normal range. In 6 of them pathologically elevated T3/T4 quotients could be observed. A TSH refractory TSH suppression was only found in patients with superior normal T4 values. After a reduction of the replacement doses the T3 values were normal. The findings show — that not only the T4 values should be controlled under treatment with thyroid preparations but also the T3 and TSH serum levels. The replacement therapy of hypothyroidism with T3/T4 preparations in proportion 1:4 should be revised.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01490240
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  • 2
    Electronic Resource
    Electronic Resource
    Psychochirurgie bei unerträglichen Schmerzen (1950)
    Springer
    Acta neurochirurgica 1 (1950), S. 1-41 
    Details
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary 1. After observations on the psychology of severe pain and on anatomy of the higher segments of the pain-system, the treatment of chronic unbearable pain is reviewed. 2. Based on the literature, psychosurgical operations against pain are discussed, above all leucotomy with its variations and topectomy. 3. Report on 10 patients with pain, 9 of whom had been treated with leucotomy and one with topectomy. 4. According to our experience, the postoperative success in the first months is frequent, but only together with a simultaneous change of the person in general. 5. Relapses occur regularly after some months. Therefore the indications of successful operations are strongly limited.
    Abstract: Résumé 1. Après des observations de la psychologie des graves douleurs et de l'anatomie des plus hauts segments du système de la douleur, on jette un coup d'oeil sur le traitement des douleurs chroniques insupportables. 2. En se basant sur la littérature médicale, on fait des opérations psychochirurgicales pour les douleurs, surtout la leucotomie avec ses variations et la topectomie. 3. Rapport sur 10 malades souffrant de douleurs, dont 9 ont été traité avec la leucotomie et 1 avec la topectomie. 4. Selon nos expériences, les succès post-opératoires dans les premiers mois sont très fréquents, mais seulement avec un changement simultané de la personne en général. 5. Après quelques mois régulièrement on constate une rechute. Les indications d'opérations couronnées par le succès sont très limitées par conséquent.
    Notes: Zusammenfassung 1. Nach Bemerkungen zur Psychologie schwerer Schmerzzustände und zur Anatomie der höheren Abschnitte des Schmerzsystems wird ein Überblick über die Behandlung unerträglicher chronischer Schmerzen gegeben. 2. An Hand der Literatur werden psychochirurgische Eingriffe bei Schmerzen, vor allem die Leukotomie mit ihren Varianten und die Topektomie besprochen. 3. Bericht über 10 eigene Schmerzkranke, von denen 9 leukotomiert und einer topektomiert wurden. 4. Nach unseren Erfahrungen sind Erfolge in den ersten Monaten post Operationem häufig, aber nur bei gleichzeitiger allgemeiner Wesensveränderung. 5. Nach einigen Monaten sind Rückfälle die Regel. Die Indikationen der erfolgreichen Eingriffe werden dadurch stark eingeschränkt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01578010
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  • 3
    Electronic Resource
    Electronic Resource
    CLINICAL USE OF RESERPINE IN PSYCHIATRY: COMPARISON WITH CHLORPROMAZINE (1955)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 61 (1955), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1955.tb42463.x
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  • 4
    Electronic Resource
    Electronic Resource
    Partial oscillator strengths (25-50 eV) of the one-electron states of CH"4^+, measured in an (e, 2e) experiment
    Amsterdam : Elsevier
    Chemical Physics Letters 37 (1976), S. 240-242 
    Details
    ISSN: 0009-2614
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0009-2614(76)80206-0
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  • 5
    Electronic Resource
    Electronic Resource
    Lateral inhibition and habituation of the human auditory cortex (2004)
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 19 (2004), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The goal of this study was to compare the lateral inhibition and the habituation in the human auditory cortex, two important physiological effects during auditory processing that can be reliably measured by means of magnetoencephalography when recording auditory evoked fields. Applying 40-Hz amplitude-modulated stimuli allowed us to record simultaneously the slow transient evoked and the steady-state fields and thus to characterize the lateral inhibition and the habituation effect in primary and non-primary auditory cortical structures. The main finding of the study is that the lateral inhibition effect of non-primary auditory areas as measured on the major component of the slow transient auditory evoked field (N1) is significantly stronger than the corresponding habituation effect. By contrast, this effect was not observed for the 40-Hz steady-state fields, characterizing the activation of the primary auditory cortex in humans. The results might be interpreted as (i) evidence that the inhibition mediated by lateral connections is stronger than the habituation of excitatory neurons in the non-primary auditory cortex and (ii) the processing hierarchy in the human auditory cortex is demonstrated by the different behaviour of lateral inhibition and habituation in primary and non-primary auditory cortical structures.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.0953-816X.2004.03296.x
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  • 6
    Electronic Resource
    Electronic Resource
    The Surface Chemistry of Bone Mineral. X. The Lack of Interaction between Sodium and Carbonate Ions (1958)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 62 (1958), S. 377-379 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/j150561a045
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  • 7
    Electronic Resource
    Electronic Resource
    The effect of antiallergic intranasal formulations on ciliary beat frequency of human nasal epithelium in vitro (1998)
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 53 (1998), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The nasal mucociliary clearance is an important defense mechanism of the upper respiratory tract. It is known to be influenced by many pharmacologic substances. We investigated the effects of three topical intranasal antiallergic formulations containing disodium cromoglycate (DNCG), dimethindene maleate (DMM), and azelastine-HCL (AZL) on nasal ciliary beat frequency (CBF) in vitro. Nasal ciliated cells were harvested from 16 healthy volunteers. Cells were diluted 1:10 in culture medium and incubated with a placebo formulation (PLAC), containing 0,022% benzalkonium chloride, which was part of all formulations, a registered 2% formulation of DNCG, a 0.1% formulation of DMM, and a registered 0.1% formulation of AZL. After an incubation period of 20 min, CBF was registered by a photoelectric measurement device. Under control conditions (CONTROL), CBF was 11 4±1 3 Hz. PLAC reduced CBF to 9.7±2.3 Hz (NS). DNCG reduced CBF t o 9.7±2 Hz (NS). DMM reduced CBF to 7.2+1.7 Hz F〈0.O5 vs CONTROL, NS vs PLAC), and AZL reduced CBF to 0.9+1.8 Hz P ≤ 0.05 vs CONTROL, P ≤ O.001 vs DNCG, P 〈 0.001 vs PLAC). In conclusion, a possible influence of antiallergic intranasal formulations on nasal ciliary function has to be considered in clinical application.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1398-9995.1998.tb03801.x
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  • 8
    Electronic Resource
    Electronic Resource
    Search for solar periodicities in Miocene tree ring widths (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Terra nova 5 (1993), S. 0 
    Details
    ISSN: 1365-3121
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: We have analysed ring-width records of two Miocene coniferous trees with an absolute age of 15–20 million years. Such data may reflect solar periodicities from the prehistoric past. Evidence for a main period of ∼ 12.5 years has been found. This is near the present basic solar activity period of ∼ 11 years. Other periodic components appear at 220, 150 and 53 years, respectively, which may also be related to solar variations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3121.1993.tb00269.x
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  • 9
    Electronic Resource
    Electronic Resource
    Photoelectron branching ratios and partial ionization cross-sections for CO and N"2 in the energy range 18-50 eV
    Amsterdam : Elsevier
    Journal of Electron Spectroscopy and Related Phenomena 8 (1976), S. 367-376 
    Details
    ISSN: 0368-2048
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0368-2048(76)80023-0
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  • 10
    Electronic Resource
    Electronic Resource
    Zur Kenntnis und Problematik des hellzelligen Adenomes in der Schilddrüse (1973)
    Springer
    Virchows Archiv 361 (1973), S. 163-173 
    Details
    ISSN: 1432-2307
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A retrospective study of 4271 surgical specimens from the thyroid gland revealed 2 morphologically benign and 6 obviously malignant clear-cell tumors. In one case, origin of the carcinoma from the thyroid gland was proven by autopsy, and another case was classified as clear-cell carcinoma of the thyroid gland because its metastases took up radioiodine. In two cases thyroid nodules were believed to be late metastases from clear-cell carcinomas of the kidney operated on some time before. In two other cases a carcinoma of the kidney was detected after extirpation of the thyroid nodules. According to morphological criteria two cases were classified as clear-cell adenomas. This rare variant of thyroid tumor is not generally considered to be benign and remains open to discussion. Clear-cell adenoma of the thyroid gland does not contain lipids or glycogen in neoplastic cells, but exhibits a characteristic ultrastructure. The cytoplasm is filled with smooth surfaced empty vesicles which are believed to derive from the Golgi apparatus. Vesicular degeneration of the cytoplasm seems to be responsible for the clear aspect of the tumor cells in histological examination. Thus the thyroid clear cell seems to be a very rare but characteristic element in neoplasia of the follicular epithelium, and might be analogous to the oxyphil cell. Criteria for the diagnostic differentiation and problems of the different clear-cell tumors of the thyroid gland are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00557845
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