ISSN:
1573-8353
Keywords:
4-hydroxyquinolone
;
carbostyril
;
1-phenylethylamides
;
optical activity
;
X-ray diffraction structural analysis
;
anticonvulsants
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract A synthesis is reported for optically pure antipodes of 1-phenylethylamides of 1-R-4-hydroxy-2-oxo-3-quinolinecarboxylic acids. An attempt was made to establish the absolute configuration of these products by X-ray diffraction crystallographic analysis. The anticonvulsant activity of the S-enantiomers was studied.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02256844
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