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  • 1
    Electronic Resource
    Electronic Resource
    Dolomitization and the genesis of the Woodcutters lead-zinc prospect, Northern Territory, Australia (1974)
    Springer
    Mineralium deposita 9 (1974), S. 175-178 
    Details
    ISSN: 1432-1866
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Conclusion Roberts' mechanism of ore genesis in this paper is plausible and is worthy of consideration. It could well apply to situations such as the Missouri-type deposits, although Gerdemann and Myers (1972) might disagree. One cannot deny that dolomitization and diagenetic processes have occurred at Woodcutters, but in view of the folding and the time-relationships exhibited by the rocks, it would appear that these are not the ultimate ore-forming processes. It is possible that the mechanism of ore genesis proposed by Roberts might apply more fully to the Bulman deposits east of Woodcutters (Patterson, 1965) where the resemblance to a Missouritype situation is stronger.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00207975
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Immunohistochemical detection of CA-125 and carcinoembryonic antigen in ovarian tumors in relation to corresponding preoperative serum levels (1992)
    238 Main Street, Cambridge, Massachusetts 02142, USA : Blackwell Scientific Publications
    International journal of gynecological cancer 2 (1992), S. 0 
    Details
    ISSN: 1525-1438
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The immunohistochemically detectable expression of CA-125 and CEA in ovarian tumor tissue from 187 patients was related to corresponding preoperative serum levels. A strong positive association between tissue expression and the serum level of both the CA-125 and CEA antigens was found in cases of invasive epithelial ovarian carcinoma. However, this relationship was absent for CA-125 in borderline cases and patients with benign ovarian tumors, although the antigen frequently was detectable in them. The presence of ascites could be verified in 3 of 10 cases with benign CA-125 negative tumors, but elevated CA-125 levels in serum. ‘False negative’ CA-125 levels were found in 6 borderline and 7 true invasive carcinoma cases despite positive tissue staining. Eight of those patients had limited stage I disease. The data suggests that although the tissue expression of the CA-125 and CEA antigens in invasive ovarian carcinoma has an important influence in the corresponding serum level, compartment barriers and low cell turnover in benign, and to a lesser extent borderline, cases result in low serum levels. In addition, other factors influence serum levels of CA-125, such as secondary peritoneal response with or without ascites, which may cause ‘falsely elevated’ CA-125 results in benign disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1525-1438.1992.02050263.x
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  • 3
    Electronic Resource
    Electronic Resource
    Tissue expression of CA-125 and carcinoembryonic antigen in ovarian carcinoma in relation to nuclear DNA content, histologic grade, and patient survival (1992)
    238 Main Street, Cambridge, Massachusetts 02142, USA : Blackwell Scientific Publications
    International journal of gynecological cancer 2 (1992), S. 0 
    Details
    ISSN: 1525-1438
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In a prospective study the immunohistochemically detectable tissue expression of the antigens CA-125 and CEA in 112 epithelial ovarian carcinomas and 23 borderline tumors was related to histologic features of the tumor and to patient survival. The CA-125 antigen was expressed mainly in non-mucinous tumors, with no evident association between histologic grade and immunoreactivity. CEA was expressed in mucinous tumors regardless of tumor grade. Flow cytometric DNA analysis was performed on fresh frozen tissue in a subgroup of 60 cases. There was no association between DNA ploidy or S-phase fraction and the CA-125 or CEA antigen expression. Tumor stage, size of residual tumor masses after surgery and DNA ploidy had independent associations with patient survival in multivariate log-rank analysis of prognostic factors. However, there was no association between the CA-125 or CEA antigen expression and patient survival. Thus, in ovarian carcinoma the expression of the CA-125 and CEA antigens seems to be independent of the inherent malignant potential of the tumor epithelium, while DNA analysis provides valuable prognostic information.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1525-1438.1992.02050271.x
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  • 4
    Electronic Resource
    Electronic Resource
    Self-reported symptom distress in cancer patients: Reflections of disease, illness or sickness?
    Amsterdam : Elsevier
    Social Science & Medicine 33 (1991), S. 1229-1240 
    Details
    ISSN: 0277-9536
    Keywords: cancer nursing ; medical anthropology ; psychosocial oncology ; salutogenic model ; sense of coherence ; symptom distress
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0277-9536(91)90071-J
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  • 5
    Electronic Resource
    Electronic Resource
    On the configuration of the 16-hydroxyl group in triterpenes: A revision
    Amsterdam : Elsevier
    Tetrahedron 29 (1973), S. 675-678 
    Details
    ISSN: 0040-4020
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0040-4020(73)80077-8
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  • 6
    Electronic Resource
    Electronic Resource
    Accuracy of dental hygienists in diagnosing dental decay (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Community dentistry and oral epidemiology 24 (1996), S. 0 
    Details
    ISSN: 1600-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract During recent decades, the duties and care rendered by Swedish dental hygienists have continuously expanded, and since 1991 they are licensed to practice dental hygiene independently. The aim of the present study was to investigate the accuracy of dental hygienists in examining and recording dental caries in comparison with dentists performing identical examinations. The study included two parts: A) Registration of carious lesions from radiographs of 100 extracted teeth, where the correct diagnosis could be verified, and B) clinical examination and registration of carious lesions in 213 patients. No statistically significant differences could be found between the dental hygienists” and their control dentists' accuracy to diagnose and record dental decay, with the exception of the number of initial lesions (white spot lesions) registered clinically, where the dental hygienists recorded more buccal and lingual lesions. Irrespective of the group of examiners (dental hygienists or dentists), however, the inter-examiner variation was wide. The variation decreased with the size of the lesion and increased with the age of the patient. This study suggests that no patient with a restorative treatment need would have been neglected if the dental hygienists had performed the examination, and, possibly, a more accurate non-restorative treatment need would have been addressed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0528.1996.tb00838.x
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  • 7
    Electronic Resource
    Electronic Resource
    Pharmacokinetics of high-dose busulphan in relation to age and chronopharmacology (1991)
    Springer
    Cancer chemotherapy and pharmacology 28 (1991), S. 130-134 
    Details
    ISSN: 1432-0843
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Busulphan levels in plasma were measured in 27 patients during conditioning therapy (1 mg/kg×4 for 4 days) before bone marrow transplantation. The mean minimal concentration found in children aged 〈5 years (237 ng ml−1) was lower than that observed in adults or older children (607 and 573 ng ml−1, respectively). The AUC for the last dose was significantly lower in young children (2,315 h ng ml−1) than in adults or older children (6,134 and 5,937 h ng ml−1, respectively). The elimination half-life for the last dose in young children was shorter (2.05 h) than that in either adults (2.59 h) or older children (2.79 h). When the AUC was normalized for body surface area, the difference between young children and the other groups was smaller but remained statistically significant. The total body clearance was significantly higher in young children (7.3 ml min−1 kg−1) as compared with both older children and adults (3.02 and 2.7 ml min−1 kg−1, respectively). The plasma levels of busulphan showed circadian rhythmicity, especially in young children. The concentration measured during the night in some patients was up to 3-fold that observed during daytime. We conclude that the busulphan dosage for children must be reconsidered and that further studies are urgently needed to develop an optimal therapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00689702
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  • 8
    Electronic Resource
    Electronic Resource
    Reaction of sulfur with organic compounds (1971)
    Springer
    Chemistry of heterocyclic compounds 7 (1971), S. 703-706 
    Details
    ISSN: 1573-8353
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The effect of the number and position of phenyl groups in a four-carbon chain on the yields of di- and triphenylthiophenes in the reaction of sulfur with phenylbutanes was investigated. New, simple methods were developed for the synthesis of 2,3-diphenylthiophene (from 1,2-diphenylbutane), 3,4-diphenylthiophene (from 2,3-diphenylbutane), 2,5-diphenylthiophene (from 1,4-diphenylbutane), and 2,3,5-triphenylthiophene (from 1,3,4-triphenyl-1-butanone). Di-, tri-, and tetrasubstituted butanes, butenes, and butadienes that contain two aromatic substituents attached to the same carbon atom do not react with sulfur under the investigated conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00476811
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