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  • 1
    Electronic Resource
    Electronic Resource
    Calculation of the nuclear spin-spin coupling constants. 3. .sigma.- and .pi.-Electron contributions in some simple unsaturated hydrocarbons (1981)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 103 (1981), S. 3652-3653 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja00403a007
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  • 2
    Electronic Resource
    Electronic Resource
    Immunological abnormalities in islets at diagnosis paralleled further deterioration of glycaemic control in patients with recent-onset Type I (insulin-dependent) diabetes mellitus (1999)
    Springer
    Diabetologia 42 (1999), S. 574-578 
    Details
    ISSN: 1432-0428
    Keywords: Keywords Type I diabetes ; insulitis ; ICA ; GAD ; biopsy ; immunohistochemistry ; HLA typing.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Aims/hypothesis. To determine whether the clinical heterogeneity observed in the development of Type I (insulin-dependent) diabetes mellitus correlates with immunohistochemical differences observed at diagnosis. Methods. Patients (n = 17) with recent-onset diabetes clinically considered to be insulin dependent (Type I), underwent pancreatic biopsy for immunohistological analysis. These patients were divided into two groups based on the presence or absence of islet immunological abnormalities (insulitis or hyperexpression of MHC class I antigens or both). The patients were also HLA typed and tested for islet cell antibodies and antibodies to glutamic acid decarboxylase (GAD-Ab). All patients were followed monthly for 2 years and their fasting plasma glucose, haemoglobin A1C and daily insulin doses were recorded. The clinical course of patients with islet immunological abnormalities was compared with that of patients without those abnormalities. Results. Patients with and without islet immunological abnormalities did not differ with regard to HLA type or islet cell antibodies. Antibodies to glutamic acid decarboxylase correlated with the presence of insulitis and MHC class I hyperexpression. These local immunological abnormalities were also associated with higher haemoglobin A1C values (p 〈 0.05) and a trend towards greater insulin requirements. Further, patients with the islet abnormalities had higher fasting plasma glucose concentrations 2 years after the biopsy than at the time of the biopsy (p 〈 0.05). Conclusion/interpretation. The heterogeneous clinical course observed following diagnosis in patients with Type I diabetes correlates with islet immunological abnormalities. Insulitis and hyperexpression of MHC class I correlate with deteriorating glycaemic control. [Diabetologia (1999) 42: 574–578]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001250051197
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  • 3
    Electronic Resource
    Electronic Resource
    Portal blood flow in the presence or absence of diffuse liver disease: measurement by phase contrast MR imaging (1995)
    Springer
    Abdominal imaging 20 (1995), S. 197-200 
    Details
    ISSN: 1432-0509
    Keywords: Magnetic resonance imaging ; Flow dynamics ; Portal vein ; Liver cirrhosis ; Chronic hepatitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: In patients with diffuse liver disease, the portal flow dynamics change markedly in accordance with disease progression and would provide a useful index of progression of stage. Methods: Portal blood flow (PBF) was measured by phase contrast magnetic resonance imaging (MRI) in 21 patients with diffuse liver disease and 20 healthy volunteers. The MRI method was validated by a flow phantom study. The mean PBF could be measured in 6.8 min without breath-holding. Results: Doppler ultrasound measurements of PBF volume were obtained reproducibly in all the healthy volunteers and were shown to correlate with the MRI values (Doppler: 12.5 ±3.2 cm3/s, MRI: 12.0 ± 3.3 cm3/s; mean ± SD). The PBF volume of patients with chronic hepatitis showed no significant difference from that of the healthy volunteers. In patients with liver cirrhosis, the PBF volume ranged from 5.01 to 32.3 cm3/s. A significant increase in PBF volume was caused in one patient by massive intrahepatic shunting and a significant decrease was caused in two patients by massive extrahepatic shunting. Conclusions: The measurement of PBF by phase contrast MRI is clinically useful in predicting intrahepatic or extrahepatic shunting in patients with liver cirrhosis, and may be of value in detecting the progression of stage in diffuse liver diseases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00200392
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  • 4
    Electronic Resource
    Electronic Resource
    Improved fluorescent microscopy for measuring the standing stock of phytoplankton including fragile components (1981)
    Springer
    Marine biology 64 (1981), S. 207-211 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Fluorescent microscopy has been used to separate autotrophic from heterotrophic microorganisms in environmental studies. We report on an improvement on this method for measuring standing stock of phytoplankton. Our method employs a membrane filter and can measure numbers of living phytoplankton including fragile flagellates and size of phytoplankton cells. This method was successfully used in Tokyo Bay and Kuroshio regions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00397110
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  • 5
    Electronic Resource
    Electronic Resource
    Determination of photosynthetic pigment composition in an individual phytoplankton cell in seas and lakes using fluorescence microscopy; properties of the fluorescence emitted from picophytoplankton cells (1986)
    Springer
    Marine biology 93 (1986), S. 343-349 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract To develop a method for the determination of photosynthetic pigment species in individual phytoplankton cells, especially natural picophytoplankton cells, the fluorescence spectra of intact cells were studied with cultured phytoplankton. The study was made mainly with phycoerythrin-containing picophytoplankton collected off Japan in 1982 with reference to diatomal species and phycoerythrin-free cyanophycean species. The spectra were measured for cell suspensions with an ordinary spectrofluorometer, and for individual cells with a microscope spectrofluorometer, paying special attention to the effect of cell-fixation. Results indicated that: (1) the cell-fixation with the glutaraldehyde and paraformaldehyde mixture modified phycoerythrin emission from picophytoplankton markedly in its wavelength location and intensity, but (2) the emission from phycocyanin was affected far less, and (3) the emission from chlorophyll a was not altered. However, the phycoerythrin emission modified by the fixation was found to be easily distinguished from other emissions, and kept its intensity high enough for detection with a fluorescence microscope. The fluorescence properties after the fixation were kept unaltered for a long period of time. Based on the results, we propose a simple method for the determination of photosynthetic pigments in individual phytoplankton cells in seas and lakes using fluorescence microscopy. Results of our tests with natural samples of phytoplankton are presented, and problems for further improvement are also discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00401101
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  • 6
    Electronic Resource
    Electronic Resource
    An anemometry technique for turbulence measurements at low velocities (1993)
    Springer
    Mineralium deposita 28 (1993), S. 547-559 
    Details
    ISSN: 1432-1866
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract A method using symmetrically bent V-shaped hot-wires has been developed for the accurate measurement of low-speed turbulence. Directional characteristics of V-shaped hot-wires at low velocities are investigated, and a generalized expression is derived for the effective cooling velocity. The measurement with V-shaped hot-wires in a pseudo turbulent field, which is artificially produced by shaking the hot-wires with an accurately known motion in a steady flow, has confirmed that the expression for the effective cooling velocity is also valid for instantaneous velocity fluctuations. The accuracy of a practical technique comprising two V-shaped hot-wires in an X arrangement is investigated by an error analysis in simulated Gaussian velocity fields using a digital computer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00624684
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  • 7
    Electronic Resource
    Electronic Resource
    Frequency response and instantaneous temperature profile of cold-wire sensors for fluid temperature fluctuation measurements (1992)
    Springer
    Experiments in fluids 13 (1992), S. 171-178 
    Details
    ISSN: 1432-1114
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The information of the wire response is necessary for the estimation of corrections and uncertainty of temperature measurements. This paper describes the theoretical response of cold-wire sensors to temperature fluctuations in a fluid flow. Existing transfer functions of cold wires are approximate and implicit functions of frequency. We present the exact solutions of heat conduction equations for a cold wire and stubs taking account of the prong effect. Because the solutions have simple forms of elementary functions, we can easily calculate the frequency response of cold wires. Sample calculations are given under several typical conditions. Also, the instantaneous temperature profiles of a cold wire are obtained for the first time.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00218164
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  • 8
    Electronic Resource
    Electronic Resource
    Human hand impedance characteristics during maintained posture (1995)
    Springer
    Biological cybernetics 72 (1995), S. 475-485 
    Details
    ISSN: 1432-0770
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Computer Science , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004220050150
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  • 9
    Electronic Resource
    Electronic Resource
    Ueber die Häufigkeit der geburtshülflichen Operationen (1909)
    Springer
    Archives of gynecology and obstetrics 89 (1909), S. 526-541 
    Details
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01929544
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  • 10
    Electronic Resource
    Electronic Resource
    Intracranial adenoid cystic carcinoma a case report (1983)
    Springer
    Acta neurochirurgica 69 (1983), S. 291-295 
    Details
    ISSN: 0942-0940
    Keywords: Computer tomography ; adenoid cystic carcinoma ; brain metastasis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A rare case of operatively verified intracranial adenoid cystic carcinoma is reported. In this case, haematogeneous metastasis to the brain parenchyma was suspected. The computer tomography showed a large hypodense mass in the left frontal lobe. The lateral wall of the tumour was irregularly enhanced with contrast media.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01401816
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