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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 22 (1974), S. 144-146 
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 38 (1966), S. 1102-1103 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 45 (1973), S. 2261-2262 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 66 (1944), S. 1259-1262 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Pure and applied geophysics 120 (1982), S. 167-185 
    ISSN: 1420-9136
    Keywords: Corsica ; Historical seismicity ; Macroseismic study
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Description / Table of Contents: Abstract The documents that we have compiled (archives, newspaper reports and seismic catalogues) enabled us to go back to the end of the 18th century in the seismic history of Corsica. The number of felt earthquakes (epicentres off shore or on the island) which were documented during the two and a half centuries is relatively low. Maximum intensities have reached VI or rarely VII. The seismic activity is mainly located in the North-East of Corsica, near faults which have recently been active between the ‘Corse schisteuse’ (Alpine domain) and the ‘Plaine Orientale’ (Quaternary, Neogene). A seismic crisis happened recently (1978–1979) in this area where present activity of some of these faults has been suggested. Macroseismic studies have been conducted for the main shocks (I max=VI and V) in order to locate them accurately. Two among them (April 3, 1978 and March 27, 1979) are studied here in detail. Using the Kövesligethy formula hypocenters are respectively found at 4.5±0.5 km and around 5 km, whereas the corresponding absorption factors are 0.020 and 0.031. Such depths show that the two events affected the upper crust of Corsica (30 km).
    Notes: Résumé L'étude des documents (archives, presse et catalogues sismiques) que nous avons consultés, nous a permis de remonter jusqu'à la fin du XVIIIe siècle dans l'histoire sismologique corse. Le nombre des séismes ressentis (épicentres en mer ou sur l'île) recensés pendant ces deux siècles et demi est relativement faible. Les intensités maximales ont parfois atteint le degré VI, plus rarement VII. L'activité sismique touche principalement une région située au Nord-Est de la Corse, au voisinage de failles au rejeu récènt et séparent le domaine de la Corse schisteuse (alpin) du domaine de la Plaine Orientale (Quaternaire, Néogène). Une crise sismique récente (1978–1979) a de nouveau secoué cette même région où on a suggéré l'activité actuelle de certaines de ces failles. Les plus importants de ces séismes (I max=VI et V) ontifait l'objet d'enquêtes macrosismiques qui permettent d'en préciser les épicentres. Deux d'entre-eux ont été étudiés en détail (3 avril 1978 et 27 mars 1979); en utilisant la relation de Kövesligethy, les hypocentres se situent respectivement à 4,5±0.5 km et vers 5 km, pour des coefficients d'absorption de 0,020 et 0,031. Ces profondeurs indiquent que ces deux séismes ont mis en jeu des éléments superficiels de la croûte corse (30 km).
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1238
    Keywords: Adrenaline ; Glucose ; Amino acids ; Urea ; Stable isotopes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective To determine the magnitude and time course of adrenergic effects on metabolism in volunteers and possible implications for the use of sympathomimetics in the critically ill. Design Descriptive laboratory investigation. Subjects 7 volunteers. Intervention Primed continuous infusions of stable isotope tracers ([15N2]-urea, [6,6-D2]-glucose, [methyl-D3]-L-leucine, [15N]-L-alanine) were used. After isotopic steady state had been reached an infusion of adrenaline (0.1 μg/kg/min) was administered (4 h). Isotopic enrichment was measured using gas chromatography-mass spectrometry and the corresponding rates of appearance were calculated. Measurements and main results Glucose production increased from 14.1±1.2 to 21.5±2.0 μmol/kg/min (p〈0.05) after 80 min of adrenergic stimulation and then decreased again to 17.9±1.2 μmol/kg/min after 240 min. Leucine and ketoisocaproate (KIC) fluxes were 2.3±0.2 and 2.6±0.2 μmol/kg/min, respectively, at baseline and gradually decreased to 1.8±0.2 and 2.2±0.1 μmol/kg/min, respectively, after 240 min of adrenaline infusion (bothp〈0.05). Alanine flux increased from 3.7±0.5 to 6.9±0.9 μmol/kg/min (p〈0.05) after 80 min of adrenergic stimulation. Urea production slightly decreased from 4.8±0.9 to 4.3±0.8 μmol/kg/min during adrenaline (p〈0.05). Conclusions Adrenaline induced an increase in glucose production lasting for longer than 240 min. The decrease in leucine and KIC flux suggests a reduction in proteolysis, which was supported by the decrease in urea production. The increase in alanine flux is therefore most likely due to an increase in de-novo synthesis. The ammonia donor for alanine synthesis in peripheral tissues and the target for ammonia after alanine deamination in the liver remain to be investigated. These results indicate that adrenaline infusion most probably will not promote already enhanced proteolysis in critically ill patients. Gluconeogenesis is an energy consuming process and an increase may deteriorate hepatic oxygen balance in patients.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-1238
    Keywords: Key words Left atrial thrombus ; Cardiac surgery ; Infant ; Recombinant tissue-type plasminogen activator ; Hemopericardium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 10-month-old boy with major left atrial thrombus following cardiac surgery was treated with intravenously administered recombinant tissue-type plasminogen activator (rt-PA; Actilyse, Thomae-Behring, Germany). The left atrial thrombus was diagnosed by Doppler echocardiography 8 days after complete correction of a ventricular septal defect. rt-PA therapy was administered over a 10-day period. Significant hemopericardium occurred 50 h after the start of thrombolytic therapy. rt-PA infusion was discontinued for 20 h to insert a pericardial drainage. The initial rt-PA dose was 0.1 mg/kg over 10 min followed by a continuous daily infusion of 1.7 mg/kg together with low-dose heparin. Thrombolytic therapy was restarted 20 h after pericardial drainage was inserted. The daily rt-PA dose was gradually raised to 3 mg/kg (total dose: 18 mg/kg). On day 7 and 8 a clear decrease in P-plasminogen and P-antithrombin occurred, requiring additional fresh frozen plasma and P-antithrombin concentrate substitution. One day later, without further side effects, complete thrombolysis occurred. Although hemopericardium demanded discontinuation of thrombolytic therapy, rt-PA administration, closely monitored by Doppler echocardiography, was continued, leading to complete thrombolysis of the left atrial thrombus in the early postoperative period. We consider the literature dealing with rt-PA thrombolysis in infancy we discuss this case report.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Intensive care medicine 22 (1996), S. S22 
    ISSN: 1432-1238
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Conclusion 1)Basal production in pig is comparable to human basal production[1]; 2) Endotoxin significantly increases the NO release; 3) Our technique allows to reliably estimate the excess endogenous NO production in hyperdynamic states as documented by the significant correlation between the changes in SVR and those of NO formation.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-1238
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-1238
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Conclusions Unlike in healthy volunteers in patients with septic shock the hepatic metabolic response to adrenergic stimulation may not mirror the catecholamine-induced increase in splanchnic blood flow. Given the high O2 cost of hepatic gluconcogenesis, infusing dobutamine may potentially reduce hepatic energy requirements in these patients.
    Type of Medium: Electronic Resource
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