ISSN:
1612-1112
Keywords:
Lonazolac
;
Precolumn enrichment
;
Direct injection
;
Serum clean-up
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary Lonazolac and its p-hydroxylated metabolite M1 are determined in serum by high performance liquid chromatography using direct injection of comparatively large volumes with precolumn enrichment. No sample workup is required prior to analysis. Reproducibility, calibration plots, recoveries and detection limits are presented, together with various applications of the method. Data from direct injection of serum are also compared to results from a conventional extraction work-up.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02258909
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