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  • 1
    Electronic Resource
    Electronic Resource
    Paper Chromatography of Amino-Acids in Cerebrospinal Fluid (1953)
    [s.l.] : Nature Publishing Group
    Nature 172 (1953), S. 358-359 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Boulanger and Biserte pass protein-free fluids through their suggested resin; but we have found as a result of Partridge's work2 that, if a sulphonated polystyrene resin of the bead type is used, protein passes through unchanged. Thus in the one operation of passing the fluid through a suitable ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/172358a0
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    THE EFFECT OF MENOPAUSAL STATUS AND SEQUENTIAL MESTRANOL AND NORETHISTERONE ON SERUM BIOCHEMICAL PROFILES (1981)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 88 (1981), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Serum biochemical profiles were compared in matched groups of premenopausal and postmenopausal women. Significantly higher concentrations of sodium, urea, calcium, albumin and alkaline phosphatase were found in the postmenopausal group. In the postmenopausal group, following treatment with sequential mestranol and norethisterone, significant reductions were recorded in the concentrations of sodium, urea, calcium, albumin, alkaline phosphatase and glucose and significant increases were recorded in the concentration of globulin and in body weight. The findings suggest that haemoconcentration may take place after the menopause and that this effect may be modified by hormone treatment. No adverse effect on liver function was noted following the hormone treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1981.tb01313.x
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  • 3
    Electronic Resource
    Electronic Resource
    THE EFFECT OF MENOPAUSAL STATUS AND SEQUENTIAL MESTRANOL AND NORETHISTERONE ON SERUM CHOLESTEROL, TRIGLYCERIDE AND ELECTROPHORETIC LIPOPROTEIN PATTERNS (1979)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 86 (1979), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The serum cholesterol, trigylcerides and electrophoretic lipoprotein patterns of 35 postmenopausal women, who subsequently received sequential mestranol and norethisterone, were compared with those of 35 premenopausal women of the same age and weight. The postmenopausal women had a significantly higher level of serum cholesterol (p 〈0.01) than the premenopausal women, and a significant reduction (p 〈0.001) occurred in this group after two months of therapy. There was no significant difference in level of serum cholesterol between the premenopausal group and the postmenopausal group receiving sequential mestranol and norethisterone for two months. The serum triglycerides were not significantly higher in the postmenopausal group but there was a significant increase (p 〈0.001) after two months of therapy. The marked alteration in lipid levels at the menopause may in part account for the great increase in coronary artery disease in postmenopausal women but whether these changes are reversible by giving hormone therapy remains speculative.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1979.tb10698.x
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  • 4
    Electronic Resource
    Electronic Resource
    The investigation of proteinuria in pregnancy using iso-dalt analysis (1984)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 91 (1984), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. Urinary protein excretion has been investigated using the iso-dalt technique in pregnant patients with hypertension and proteinuria, without hypertension but with proteinuria and without either hypertension or proteinuria. This high resolution electrophoretic technique has shown a great variation in the pattern of protein excreted by these patients, particularly those with hypertension. These showed an increased number of protein species in the urine, some of unknown identity. Two urines from this group appeared to contain no detectable albumin. Currently this technique is inappropriate for the routine analysis of urine proteins. However, further studies may determine the diagnostic value of these changes in urine excretion and allow the development of more specific assays.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1984.tb03674.x
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  • 5
    Electronic Resource
    Electronic Resource
    THE EFFECT OF VARIOUS REGIMENS OF HORMONE THERAPY ON SERUM CHOLESTEROL AND TRIGLYCERIDE CONCENTRATIONS IN POSTMENOPAUSAL WOMEN (1980)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 87 (1980), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The serum cholesterol and triglyceride concentrations of 84 postmenopausal women both before and after 2, 6 and 12 months therapy with various regimens of hormone therapy were measured. There was little alteration in mean serum cholesterol concentration with cyclical oestrogens but both sequential mestranol and norethisterone and sequential oestradiol valerate and norgestrel significantly reduced the mean serum cholesterol concentration to a level similar to that found in age-matched premenopausal women. There was a small and sometimes significant rise in serum triglyceride concentration with cyclical oestrogens. Sequential mestranol and norethisterone significantly elevated serum triglyceride levels, but sequential oestradiol valerate and norgestrel significantly depressed them. The results suggest that the progestogenic agent norgestrel has an important role to play in reducing both serum cholesterol and triglyceride levels, and that the sequential preparations, by virtue of their greater cholesterol lowering effect, should perhaps be preferred to cyclical oestrogens.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1980.tb05002.x
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  • 6
    Electronic Resource
    Electronic Resource
    Gastric hypersecretion following massive small-bowel resection in man (1967)
    Springer
    Digestive diseases and sciences 12 (1967), S. 785-794 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Gastric hypersecretion following small-bowel resection in man has previously only received brief mention. This paper is a case report of a man who, following a massive bowel resection for mesenteric emboli, required repeated gastric aspiration and was shown to have gastric hypersecretion with a daily volume of 2–4 L. containing 200–500 mEq. of hydrogen ion. This hypersecretion resulted in gross biochemical abnormalities which, along with their phase of correction, were studied in detail. Possible mechanisms for this hypersecretion are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02236243
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    An enhanced chemiluminescent enzyme immunoassay for serum carcinoembryonic antigen based on a modification of a commercial kit (1986)
    New York : Wiley-Blackwell
    Journal of Bioluminescence and Chemiluminescence 1 (1986), S. 29-34 
    Details
    ISSN: 0884-3996
    Keywords: Enhanced chemiluminescence ; enzyme immunoassay ; carcinoembryonic antigen ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: A conventional colorimetric peroxidase end-point (ortho-phenylenediamine substrate), used in an enzyme immunoassay for carcinoembryonic antigen, employing plastic beads as solid support, has been replaced by a much faster (30 seconds versus 30 minutes) enhanced chemiluminescent assay for the peroxidase label. Para-iodophenol was used to enhance the light emission from the peroxidase catalysed chemiluminescent reaction between luminol and hydrogen peroxide. Values for precision and carcinoembryonic antigen concentration obtained with the chemiluminescent and colorimetric versions of the immunoassay on 62 serum specimens were in good agreement.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bio.1170010106
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