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  • 1
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 22 (1950), S. 1561-1562 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 42 (1986), S. 537-542 
    ISSN: 1420-9071
    Keywords: Annual ring ; beech ; trace metals ; environmental pollution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Annual rings of 140–160-year-old beeches (Fagus sylvatica) from St. Ingbert, Saarland (FRG) were prepared and analyzed for 14 metals by atomic absorption spectroscopy. According to the chronological variations of their concentrations, the elements could be divided into three groups: 1) Metals without any tendency for chronological changes. This was established for Na, K, Cu, Cr, Co, Ni, Pb, and Cd. 2) Metals with a recent decrease of their concentrations, appropriate for Ca, Mg, Mn, and Zn. 3) Metals with a recent tendency to increase, e.g. Fe and Al. These variations are discussed in connection with the industrial history of the Saarland region and the influence of acid immissions which may alter the soil and thereby the trace element metabolism of the trees with consequences for the vitality of the plants.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 168 (1983), S. 341-348 
    ISSN: 1432-0568
    Keywords: Presynaptic perikarya of interneurons of LGN ; Night-active prosimian and simian ; EM ; Degeneration of retino-geniculate terminals
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The lateral geniculate nucleus (LGN) of Aotus trivirgatus and Nycticebus coucang shows two types of neurons at the ultrastructural level: a large thalamo-cortical relay neuron (TCR) and a small neuron of Golgi type II, which is considered to be an interneuron. The interneuron contains small aggregations of synaptic vesicles in the perikaryon adjacent to the cell membrane in synaptic contact to a TCR neuron. Only in the perikaryon of the interneurons can cilia have their origin. After unilateral enucleation, neurofilamentous or dark degenerations of large boutons with round vesicles (type RL) occur in the outer layers of the contralateral LGN and in the inner layers of the ipsilateral LGN. The optic terminals establish synaptic contacts in the glomerulus with dendritic spines of the TCR neurons and with presynaptic dendrites (F2) of interneurons.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 5 (1926), S. 2100-2107 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 6 (1927), S. 1982-1984 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung 1. Die Frage, ob es ein die Nährstoffresorption förderndes inneres Sekret der Bauchspeicheldrüse gibt, wird in der neuesten Literatur als unentschieden hingestellt. 2. Es wird deshalb der Einfluß des Insulins auf die Nährstoffresorption geprüft a) bei pankreaserkrankten Menschen mit schweren Resorptionsstörungen, b) bei pankreaslosen Hunden. Es zeigt sich, daß Insulinmengen, die die pathologische Kohlehydratstörung beseitigen, keinerlei Einfluß auf die Nährstoffresorptionsstörung haben. 3. Unterbindung sämtlicher Ausführungsgänge des Pankreas führt zu den gleichen schweren Resorptionsstörungen wie Pankreasexstirpation. 4. Es wird daraus geschlossen, daß es ein die Nährstoffresorption förderndes inneres Sekret des Pankreas nicht gibt.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 46 (1968), S. 1226-1227 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary J131 triolein was applicated by a duodenal tube to 27 patients. The radioactivity of the blood and the feces was compared with the results, obtained by peroral feeding of the labeled fat. The results indicate, that the advantage of a defined exposition of the labeled triolein to the fat-splitting enzymes and to the small bowel surface is equalized by the disadvantage of ineffective hydrolysation of the fat due to inadequate stimulation of the pancreas. So this modification of the J131 triolein test can not be favoured for clinical uses.
    Notes: Schlußfolgerung Aus diesen Ergebnissen wurde der Schluß gezogen, daß durch die intraduodenale Instillation die J131-markierten Testlipide den Verdauungsenzymen und dem eigentlichen Resorptionsprozeß zwar zu einem definierten Zeitpunkt exponiert werden, dafür aber andere Störfaktoren, vor allem eine ungenügende Hydrolyse der Testlipide infolge inadäquater Pankreasstimulation in Kauf genommen werden müssen, so daß diese Modifikation des J131-Trioleintest für die klinische Diagnostik nicht geeignet ist. Selbst die vorherige Gabe einer Reizmahlzeit [2] oder der Gebrauch pankreasstimulierender Hormone [3] vermag aus den oben erwähnten Gründen den diagnostischen Wert dieser Modifikation nicht entscheidend zu verbessern.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 45 (1967), S. 1056-1056 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary For quantitative determination of fecal protein losses the following procedure was employed: The feces were homogenized in a blender. Depending on th consistency of the feces, especially in normal persons water had to be added in a ratio 2:1 or 1:1 (w/w). An aliquot was centrifuged in a high speed centrifuge (Servall SS1) at 16000 rpm for 5 hours. The supernatant was filtered. The proteins of 1–2 ml of this fluid were precipitated with ethanol (end concentration 80%). After repeated washings of this precipitate with ethanol, the N-content was determined by a Mikrokjehldahl-method. Another aliquot of the original mixture was freeze dried, thus determining the dry wight and the whole fluid content of the feces vice verse. From these data, the daily protein losses were calculated. 10 normal persons had a mean protein loss of 0,51 g a day. (range 0.19–0.85 g). In patients with ulcerative colitis or enterocolitis this figures went up to 13,7 g/24 hours. One patient with protein loosing enteropathy due to intestinal lymphangiectasis excreted between 6 and 36 g proteins a day.
    Notes: Zusammenfassung Es wird eine Methode zur quantitativen Bestimmung der in den Faeces ausgeschiedenen Proteine beschrieben. Mit dieser Methode fand man bei zehn darmgesunden Versuchspersonen eine Proteinausscheidung von 0,19–0,85, im Mittel 0,51 g/24 h. Vier Patienten mit Colitis ulcerosa schieden demgegenüber zwischen 3,2 und 13,7 g Protein/24 h, ein Patient mit enteralem Proteinverlust infolge intestinaler Lymphangiektasie sogar zwischen 6,2 und 35 g/Protein/24 h aus.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 44 (1966), S. 398-402 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Thinlayer- and columnchromatographic studies on brain gangliosides of Tay-Sachs-disease indicate, that the increase of gangliosides in Tay-Sachs brain is due to the accumulation of a fast moving fraction. In normal child brain only traces of this fraction are detectable. The quantitative analysis displays as building blocks sphingosin, stearic acid, galactose, glucose, galactosamin and N-acetyl-neuraminic acid in a molar ratio of 1:1:1:1:1:1, thus indicating that the T.S.-ganglioside is different from the normal gangliosides by the lack of one mol galactose. The normal tri-di- and monosialogangliosides account for ∼1% of the dry weight of the Tay-Sachs-brain. This is about the same percentage as it is in normal child brain. Quantitative studies of the “normal” gangliosides of Tay-Sachs brain showed them identical with gangliosides of normal child brain. One therefore may assume, that in Tay-Sachs-disease the formation of gangliosides is normal and that the accumulation of gangliosides is due to a defective degradation of the monosialoganglioside GIV.
    Notes: Zusammenfassung Die Vermehrung der Ganglioside bei der Tay-Sachsschen Erkrankung beruht nach chromatographischen Untersuchungen auf der Akkumulation einer Fraktion, die normalerweise nur in Spuren vorkommt. Diese Fraktion unterscheidet sich von den vier Gangliosidfraktionen, die den Hauptanteil normaler Gangliosidpräparationen ausmachen, durch das Fehlen eines Mol Galaktose im Gangliosidmolekül. Die vier normalerweise vorhandenen Gangliosidfraktionen mit dem molaren Galaktose-Glucoseverhältnis 2:1 haben auch bei der Tay-Sachsschen Erkrankung mit ca. 1% den gleichen quantitativen Anteil am Hirntrockengewicht wie im normalen kindlichen Gehirn. Es liegt also offenbar kein Defekt in der Produktion normaler Ganglioside vor. Über die Ursache des gestörten Abbaues oder der Metabolisierung der abnorm akkumulierten Gangliosidfraktion mit dem molaren Galaktose-Glucoseverhältnis von 1:1 können keine Aussagen gemacht werden.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 11 (1932), S. 1764-1766 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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