ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
The in vivo study was performed to evaluate the biocompatibility and osteogenous ability ofinjectable fast-setting calcium phosphate cement (CPC). Eighteen four-week-old New Zealand whiterabbits were divided into six groups randomly, three in each group. According to the principle of selfcontrastat the same time, cavities of 5mm in diameter and 6mm in depth were drilled in femoral condyleof rabbits. The materials were implanted into cavities of the left leg, the right leg as the blank controlgroup. Rabbits were sacrificed at 2, 4, 8, 12, 16 and 24 weeks after surgery. The microstructure ofspecimens was observed using ESEM. The results showed that injectable fast-setting CPC had goodfluidity and plasticity; it could be injected into bone defects and fast-set in situ. The start setting time was5-8 min and the compressive strength was 25-30 MPa. The CPC had good biocompatibility andosteoconductivity, and benefited to the repair of bone defects
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/53/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.336-338.1625.pdf
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