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  • 1
    Electronic Resource
    Electronic Resource
    Determination of lactose malabsorption by breath analysis with gas chromatography (1976)
    s.l. : American Chemical Society
    Analytical chemistry 48 (1976), S. 393-398 
    Details
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ac60366a039
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Effect of a nonlactose diet on human intestinal disaccharidase activity (1968)
    Springer
    Digestive diseases and sciences 13 (1968), S. 593-597 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Total lactose abstinence for 42 days in 7 subjects failed to induce a deficiency in intestinal lactase or clinical lactose intolerance. Therefore, dietary lactose content does not appear to be an important factor in determining the level of intestinal lactase in humans for this period of time.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02232965
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Effects of age on lactose malabsorption in Oklahoma Native Americans as determined by breath H2 analysis (1977)
    Springer
    Digestive diseases and sciences 22 (1977), S. 113-116 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Breath H2 excretion was used to determine lactose malabsorption in 30 healthy females and 30 healthy males between the ages of 3 and 64 yr who were at least 7/8 Native American. The test meal consisted of 5 ml reconstituted nonfat dry milk (0.25 g lactose) per kg of body weight. On the basis of breath H2 tests in 15 control subjects with normal oral lactose tolerance tests, a response factor of 20 ppm was selected as the upper limit for lactose absorbers. Of the 60 subjects in the study group, 36 (60%) were classified as lactose malabsorbers since they had a response factor of 20 ppm or greater of breath H2. Only 3 of 20 children (15%) who were under the age of 12 yr were nondigesters of the small lactose dose used in this study. Approximately 82 percent (82.5%) of subjects who were 13 yr and older were lactose malabsorbers. Adolescence appears to be the period in which malabsorption of lactose becomes evident in Native North Americans.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01072952
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Lactose malabsorption and steatorrhea (1972)
    Springer
    Digestive diseases and sciences 17 (1972), S. 533-538 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Twenty-seven patients with an isolated lactase deficienty (ILD) had fecal fat studies on 45 occasions, and 9 individuals had steatorrhea at some level of oral lactose intake. The degree of steatorrhea in the individual patient was related to the amount of lactose ingested. Analysis of the stool triglycerides indicated that the steatorrhea was due to a postlipolytic rather than a lipolytic defect. Steatorrhea was also not related to the presence of diarrhea, as calculated from stool wet-weight, nor was diarrhea related to the amount of dietary lactose ingested. No correlation was found between the presence of an abnormal D-xylose excretion test and lactose-induced steatorrhea. From our data and those in the literature, it would appear that individuals with an ILD who have had gastric surgery or small intestinal resections, or have mucosal abnormalities, are most inclined to develop lactose-induced steatorrhea.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02231210
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Adequacy of endoscopic biopsy specimens for disaccharidase assays (1978)
    Springer
    Digestive diseases and sciences 23 (1978), S. 1129-1131 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Intestinal mucosa from 40 patients obtained by fiber-endoscopic biopsy was assayed for disaccharidases to determine suitability of this tissue for assay. The combined specimens from each patient provided 4.7–38.7 mg of tissue, adequate in all instances for duplicate determinations of protein, lactase, sucrase, and maltase. Tissue remained for assays of palatinase in 39 instances, trehalase and cellobiase in 37, and alkaline phosphatase in 22 cases. Twenty-four subjects had normal lactose tolerance tests and normal sucrase/lactase ratios. Thirteen patients with abnormal oral lactose tolerance tests were identified as having a primary low lactase activity on the basis of elevated sucrase/lactase ratios. This ratio was most helpful in making the diagnosis of a primary low lactase, since the mucosal specimens were not obtained from comparable areas. Tissue from three subjects with an abnormally low maltase was unsuitable for diagnosis. Endoscopic biopsy of mucosa appears to be satisfactory for disaccharidase assays in most instances.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01072890
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    Paper (German National Licenses)
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