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  • 1
    Electronic Resource
    Electronic Resource
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part B: Polymer Physics 30 (1992), S. 293-297 
    ISSN: 0887-6266
    Keywords: poly(p-phenylene) from organometallic polymerization, crystal structure of ; crystal structure of poly(p-phenylene) from organometallic preparation ; X-ray diffraction of organometallically produced poly(p-phenylene) ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The two-dimensional crystal structure of poly(p-phenylene) is investigated by linkedatom Rietveld analysis of the x-ray diffraction powder profile. Two molecular chains are packed in a rectangular pgg unit cell (a = 0.779 nm; b = 0.551 nm) with a paracrystalline shift distortion along the chain axis. The molecular conformation is not rigidly planar; rotations between adjacent phenyl-ring planes in a molecule alternate with an angle of about 20°. The setting angle between the mean molecular plane and the a axis is 55.5°.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 117-118 (Jan. 1993), p. 523-524 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Development genes and evolution 206 (1996), S. 64-71 
    ISSN: 1432-041X
    Keywords: Key words Annexin V ; Spermatogenesis ; Meiosis ; Cynops pyrrhogaster ; Differential screening
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  In order to isolate genes whose expression is up-regulated after the initiation of meiosis, we screened a cDNA expression library of newt testes with antiserum against homogenates of testes derived from the spermatogonial and spermatocyte stages. We report the isolation of spermatocyte-specific cDNA clones encoding a newt homologue of the calcium-dependent phospholipid-binding protein, annexin V. Northern blot analysis showed that newt annexin V mRNA was 1.7 kb in length and was expressed strongly in testes, but weakly in other organs. In situ hybridization revealed that the expression of newt annexin mRNA was barely observed in spermatogonia, but increased significantly in leptotene-zygotene primary spermatocytes and reached a maximum level in pachytene spermatocytes and round spermatids. The newt annexin V cDNA predicted a 323-amino acid protein and had a 68% homology to human annexin V. The predicted amino acid sequence contained a conserved 4-fold internal repeat of approximately 70 residues like other annexin proteins. Immunoblot analysis using the monoclonal antibody against newt annexin V showed that the protein was expressed scarcely in spermatogonia but was abundantly expressed in stages from primary spermatocytes to spermatids; this pattern was consistent to that of the mRNA. Immunohistochemical analysis revealed that newt annexin V was localized in the cytoplasm of the spermatogenic cells, but not in somatic cells such as Sertoli cells or pericystic cells. These results indicate that the expression of newt annexin V is up-regulated in the spermatogenic cells after the initiation of meiosis and suggest that newt annexin V plays an important role in spermatogenesis.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0992-7689
    Keywords: Ionosphere (Auroral, ionosphere) ; Magnetospheric Physics (Magnetotail; Storms and substorms)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract During the 6th August 1995, the CUTLASS Finland HF radar ran in a high time resolution mode, allowing measurements of line-of-sight convection velocities along a single beam with a temporal resolution of 14 s. Data from such scans, during the substorm expansion phase, revealed pulses of equatorward flow exceeding ∼600 m s−1 with a duration of ∼5 min and a repetition period of ∼8 min. Each pulse of enhanced equatorward flow was preceded by an interval of suppressed flow and enhanced ionospheric Hall conductance. These transient features, which propagate eastwards away from local midnight, have been interpreted as ionospheric current vortices associated with fieldaligned current pairs. The present study reveals that these ionospheric convection features appear to have an accompanying signature in the magnetosphere, comprising a dawnward perturbation and dipolarisation of the magnetic field and dawnward plasma flow, measured in the geomagnetic tail by the Geotail spacecraft, located at L = 10 and some four hours to the east, in the postmidnight sector. These signatures are suggested to be the consequence of the observation of the same field aligned currents in the magnetosphere. Their possible relationship with bursty Earthward plasma flow and magnetotail reconnection is discussed.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 41 (1985), S. 1456-1457 
    ISSN: 1420-9071
    Keywords: Granulocyte ; complement ; immune adherence ; immune deposit ; glomerulonephritis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Sections of rat kidney with bovine serum albumin nephritis were incubated either with a single component of complement or with several components in sequence and then reacted with granulocytes. The average number of granulocytes bound to a nephritic glomerulus was elevated in sections incubated with C4 or C3 and increases were most significant when C14, C142 or C1423 were incubated.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1420-9071
    Keywords: Estrogen ; receptor ; tumor ; submandibular gland ; 9,10-dimethyl-1,2-benzanthracene ; female rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract We have demonstrated the presence of estrogen receptor mRNA and the mature protein in the cytoplasm and nucleus, respectively, of a 9,10-dimethyl-1,2-benzathracene-induced submandibular gland tumor in female rats. We have previously shown that progesterone receptors are also present in human salivary gland tumors. These results suggest that endocrine therapy may be effective in treatment of submandibular gland tumors.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0568
    Keywords: Key words Cellular cementum ; Intrinsic fiber ; Cementoblast ; Human tooth
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The formation of an alternate lamellar pattern in the advanced stage of cellular cementogenesis in human molars was examined by light and electron microscopy. In longitudinal ultrathin sections, longitudinally oriented intrinsic fibril bundles appeared in close and parallel association with slender processes of cementoblasts on the cementum. Where transversely oriented intrinsic fibril bundles appeared, cementoblasts formed indentations to enclose the fibril bundles. Cytoplasmic fragments were also enclosed in the indentations. Scanning electron microscopy indicated that cementoblasts have developed two types of processes on their cementum-facing side – ridge- and finger-like. The cementoblasts formed groove-like compartments by ridge-like processes in cooperation with other cementoblasts. The compartments formed groups, and in each group the compartments were arranged in the same direction. The finger-like processes were arranged in parallel with the ridge-like processes in the compartments. These observations suggest that: (1) slender processes and cytoplasmic fragments are longitudinally and transversely cut finger-like processes, respectively; (2) the cellular indentations are transversely cut groove-like compartments; (3) the cementoblasts regulate the intrinsic fiber arrangement by the two types of processes; (4) the cementoblasts move the two types of processes synchronously and periodically to cause an alternate change in the intrinsic fiber arrangement. This dynamic sequence results in the alternate lamellar pattern of cellular cementum.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-0568
    Keywords: Keywords Cementoblasts ; Collagen fibrils ; Lamellar structure ; Maceration ; Scanning electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Human cellular cementum was examined by scanning electron microscopy to elucidate the manner of the alternate lamellar pattern forming the cellular cementum. Specimens were demineralized, trimmed with a freezing microtome, and treated by NaOH-maceration. This procedure was chosen to avoid artifacts in the fibril arrangement, and to study the fibrous architecture in detail. For comparison, non-demineralized, polished and HCl-etched specimens were also prepared. In the NaOH-macerated specimens, the lamellar pattern of the cellular cementum conformed to the twisted plywood principle of bone lamellation with a periodic rotation of matrix fibrils resulting in an alternating lamellar pattern. In contrast, matrix fibrils were irregularly arranged without indication of rotation of matrix fibrils in the polished and etched specimens. Our results suggest that polishing and etching procedures cause damage to fibrils and fibril arrangement.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-0533
    Keywords: Herpes simplex ; Encephalo-myelo-neuritis, experimental ; Infection Pattern and Age ; Fluorescent Antibody Method ; Tissue Susceptibility
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Modifikation des Infektionsmusters im Zentralnervensystem und in den Körperorganen von 108 Mäusen, die zu verschiedenen Zeiten, vom Neugeborenen bis 30 Tage alt, mit Herpes simplex-Virus intraperitoneal inoculiert worden waren, wurde mit der Fluorescenz-Antikörpermethode untersucht. Der DD-Stamm von Mäusen war viel empfänglicher gegen Herpes simplex-Virus als der C57BL-Stamm. Die Stärke der Affektion in der Lunge und Leber nimmt parallel mit dem Alter ab. Keine Läsion wurde in der Leber der über 7tägigen Mäuse verursacht. Während der Dauer des Experiments war eine hohe Sensitivität im Gastrointestinaltrakt bemerkbar. Das Nervensystem zeigte eine mäßig starke Empfänglichkeit in allen Zeiten der Entwicklung. Die Regionen, in denen Veränderungen des Infektionsmusters bestanden, waren Groß- und Kleinhirn, dabei war eine markante, doch vorübergehende Steigerung der Infektionsrate bei 7 tägigen Mäusen auffällig. Die Zunahme der Ansprechbarkeit im Großhirn fiel mit einer topistischen Vulnerabilität des Temporallappens und Hippocampus zusammen. Peripherien der sympathischen und spinalen Nerven tendierten zu stärkerem Befall bei einem Alter über 14 Tage. Im Rückenmark war die Läsion am häufigsten und von stabilem Muster. Durch den Verlauf des Alters gab es keine wesentliche Veränderung der Wirtzellen des ZNS. Die perivasculäre Zellinfiltration fand sich in den parenchymatösen Läsionen des ZNS bei 21 Tage alten Mäusen. Es gab keine deutliche Ansammlung der Virus-Antigene in der direkten Umgebung der Zellinfiltration. Rolle und Bedeutung gewisser Faktoren, wie der Weg für Viruswanderung, Virämie und Empfänglichkeit des Gewebes, die die Modifikation des Infektionsmusters im ZNS möglicherweise beeinflussen, werden in Beziehung zur Alterung der Tiere erörtert.
    Notes: Summary The modification of infection pattern in the nervous system and viscera of one hundred and eight mice, which were administered intraperitoneally with herpes simplex virus at various stages of growth ranging from newborn to 30 days old, was investigated with fluorescent antibody method. DD strain mouse was proved to be far more susceptible than C57BL strain mouse. The lung and liver became less affected in parallel with advance of age, particularly complete absence of infection occurred in the latter organ of even one week old. The gastrointestinal tracts retained high sensitivity through the experiment. The nervous system displayed a fair susceptibility in all periods of growth. The regions showing definite change of infection were the cerebrum and cerebellum, in which marked but transient increase of infection rate was demonstrated at one week of age. The elevation of infectability in the cerebrum was accompanied by certain topistic vulnerability as seen in the temporal cortex and hippocampus. Peripheries of sympathetic and spinal nerves tended to be more extensively involved after two weeks of age. The spinal cord was representative of lesions with high incidence and stable pattern of infection. No essential change occurred in the range of host cells of the nervous system through the course of aging. The perivascular cellular cuffing took place in the parenchymal lesions of the central nervous system in three weeks old mice. There was no precise accumulation of virus antigen lining the cuffs. The role and significance of virus pathways, viremia and tissue susceptibility as possible factors taking part in the pattern modification in central nervous system infection were discussed in connection with aging of animals.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 67 (1985), S. 296-299 
    ISSN: 1432-0533
    Keywords: Parkinsonism-dementia complex of Guam ; Nucleus raphe dorsalis ; Alzheimer's disease ; Morphometry ; Neurofibrillary tangles
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Recently, morphometric analysis has shown that the nucleus raphe dorsalis, which is presumed to project diffuse serotonergic fibers to the telencephalon, is affected in Alzheimer's disease. A similar study was conducted in this report in two patients with parkinsonism-dementia complex of Guam and a Guamanian control. It demonstrated a significant reduction in the number of large neurons, and the presence of abundant Alzheimer's neurofibrillary tangles in this nucleus.
    Type of Medium: Electronic Resource
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