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  • 1
    Electronic Resource
    Electronic Resource
    Morphological study on the hereditary neurogenic amyotrophic dogs: Accumulation of lipid compound-like structures in the lower motor neuron (1983)
    Springer
    Acta neuropathologica 61 (1983), S. 270-274 
    Details
    ISSN: 1432-0533
    Keywords: Dog ; Motor neuron disease ; MCBs ; Zebra body ; Metabolic disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A morphological study was performed on hereditary neurogenic amyotrophic dogs, the clinical features of which especially resembled spinal progressive muscular atrophy (SPMA), a human motor neuron disease. The skeletal muscles showed obvious neurogenic atrophy with endomysial fibrosis. The peripheral nerves revealed axonal degeneration mainly limited to the motor nerve. In the spinal cord, the number of anterior horn cells seemed normal but, interestingly enough, numerous accumulated granules were detected in these anterior horn cells. Histochemically, these granules were interpreted as a lipid compound. Under the electron microscope, the granules were disclosed as multi-lamellar structures, arranged concentrically or in parallel, resembling membranous cytoplasmic bodies (MCBs) or zebra bodies. This finding strongly suggests that hereditary abnormality of lipid metabolism may underlie SPMA in these dogs. However, unlike other metabolic disorders where accumulations of granules are diffusely distributed, in the dogs we examined accumulations were found only in the anterior horn cells of the spinal cord and in the hypoglossal and spinal accessory nuclei. We are unable to explain this occurrence at the present time. Further investigations should be made on dogs because they serve as an important animal model of human motor neuron disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691997
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  • 2
    Electronic Resource
    Electronic Resource
    EVALLUTION of FIBER INGREDIENTS PRODUCED BY ENZYMIC AND/OR YEAST FERMENTATION of TRITICALE (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food processing and preservation 14 (1990), S. 0 
    Details
    ISSN: 1745-4549
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: The chemical composition, nutritional properties, and functional characteristics of various fiber ingredients prepared by enzymic and yeast fermentation of triticale were evaluated. Drying and other processing parameters, including the effect of varying the level of residual starch, sugar, or soluble solids on ingredient composition were determined. Triticale fiber ingredients produced by fermentation had similar in vitro protein digestibility values compared to products made from wheat. Levels of Fe, Ca, and Zn were higher in triticale fiber ingredients than for comparable wheat fiber products, bran, or oat bran, suggesting that the nutrient availability for these minerals may be higher for triticale products. These fiber ingredients from triticale were incorporated at flour replacement levels of up to 15% (w/w) in yeast raised bread, yielding products with acceptable color, appearance and crumb grain scores products. Comparative data for other fiber ingredients are also presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-4549.1990.tb00146.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Reversed-phase high-performance thin-layer chromatography of mono-, di- and trisubstituted bile acid methyl esters (1983)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 6 (1983), S. 617-620 
    Details
    ISSN: 0935-6304
    Keywords: High-performance thin-layer chromatography, HPTLC ; Reversed-phase ; Octadecyl-bonded silica gel ; Bile acid methyl esters ; Methyl 5β -cholanates ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A comparative study is reported on separation of series of mono-, di-, and trisubstituted methyl 5β-cholanates, which differ only in the position and stereochemistry of hydroxyl or keto groups at position and stereochemistry of hydroxyl or keto groups at positions C-3, C-7, and/or C-12, by reversed-phase [with chemically-bonded (C-18) silica gel] and normal-phase (silica gel) high-performance thin-layer chromatography (HPTLC). Methnol (or acetonitrile)/water systems were employed as mobile phase. Reversed-phase HPTLC found to be particulary effective for separation of the stereoisomers of di- and trisubstituted compounds whereas the less polar monosubstituted isomers are well resolved in normal-phase HPTLC.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240061106
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    Paper (German National Licenses)
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