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  • 1
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1520-6041
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-072X
    Keywords: Key wordsmip Gene ; Mip protein ; FK506-binding proteins ; FKBP ; Legionella pneumophila ; Escherichia coli
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A newly identified gene in Escherichia coli, fkpA, encodes a protein with extensive similarity to the macrophage infectivity potentiator (Mip) proteins of Legionella pneumophila and Chlamydia trachomatis. The FkpA protein may be a new member of the family of FK506-binding proteins (FKBPs) because its carboxyl domain includes a sequence that matches the consensus FK506-binding motif in 40 of 48 positions, including those amino acids at the active site that form hydrogen bonds with the drug FK506. The amino acid sequence of the 29 kDa FkpA protein is 30–35% identical to the Mip proteins of L. pneumophila, L. micdadei, and C. trachomatis. Of the 270 amino acids of FkpA, 113 (42%) are identical to the sequence of one or another of these Mip proteins. Overexpression of FkpA or deletion of fkpA from the E. coli chromosome had no detrimental effect on bacterial growth, indicating that fkpA is not an essential gene. Hybridization of fkpA-specific DNA probes to genomic blots revealed that similar genes exist in several representatives of the Enterobacteriaceae. Thus, mip-like genes are not found exclusively in bacteria having a predominately intracellular life style, but instead appear to be a new FKBP subfamily that is a common constituent of many bacteria.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Archives of microbiology 161 (1994), S. 501-507 
    ISSN: 1432-072X
    Keywords: Key words:Escherichia coli–Salmonella typhimurium–murB–rrfB– Repetitive extragenic palindrome – Evolution – Mutation rate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract. The murB gene of Salmonella typhimurium was cloned and found to be 75% and 82% identical to the DNA and protein sequences, respectively, of the same gene in Escherichia coli. These identities are among the lowest recorded between the two bacteria. Nevertheless, wild-type S. typhimurium murB complemented the known temperature-sensitive E. coli mutant, and wild-type E. coli murB complemented three temperature-sensitive mutants of S. typhimurium. The 5S rRNA gene, rrfB, and the region between murB and rrfB were also cloned and sequenced. The rrfB gene of S. typhimurium differs from rrfB of E. coli in only 2 of 120 nt, but the region between murB and rrfB has diverged greatly and includes a sequence that closely resembles a repetitive extragenic palindrome of the type normally associated with E. coli. Previous comparisons of gene divergence have suggested that the chromosomal mutation rate is lower in the vicinity of the origin of replication. However, the S. typhimurium murB gene, located 6 map minutes from the origin of replication, is highly substituted at synonymous sites and the sequence between murB and rrfB is significantly modified as well. Thus, murB is an exception to the general observation that genes near the origin of replication show less divergence than do genes elsewhere in the bacterial chromosome.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 89 (1988), S. 2894-2899 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The enhanced tranfer of energy between donor and acceptor molecules in a micrometer size aerosol particle due to the presence of sharp morphology dependent resonances is discussed quantum mechanically. By making use of density of states and quasimode concepts, it is shown that the enhancement factor depends only on the quality factor Q of the resonances, but not on the mode functions, therefore yielding results valid for any microparticle geometry (for which the mode functions are, in general, unknown). Emphasis is also placed on the absorption dominated limit (easily reached in practice), in which the result is particularly simple.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A bent quartz-crystal spectrometer of the Johann type with a spectral resolution of λ/Δλ= 10000–25000 is used on the Tokamak Fusion Test Reactor (TFTR) to determine central plasma parameters from the spectra of helium-like and lithium-like metal impurity ions (Ti, Cr, Fe, and Ni). The spectra are observed along a central radial chord and are recorded by a position-sensitive multiwire proportional counter with a spatial resolution of 250 μ. Standard delay-line time-difference readout is employed. The data are histogrammed and stored in 64 K of memory providing 128 time groups of 512-channel spectra. The central ion temperature and the toroidal plasma rotation are inferred from the Doppler broadening and Doppler shift of the Kα lines. The central electron temperature, the distribution of ionization states, and dielectronic recombination rates are obtained from satellite-to-resonance line ratios. The performance of the spectrometer is demonstrated by measurements of the Ti xxi Kα radiation.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 56 (1985), S. 830-832 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: An array of 64 silicon surface-barrier diodes on a circular arc view Tokamak Fusion Test Reactor (TFTR) plasmas through a slot aperture to provide poloidal imaging of x-ray emission in the 200 eV–15 keV range. Information is inferred on magnetohydrodynamic (MHD) instabilities, disruptions, radiation, impurity transport, electron temperature, and electron thermal conductivity. Spatial resolution is 2.5 cm. Movable absorber foil arrays provide energy selection. Preamplifier–amplifier pairs have gains of 0.05–100 V/μA. Two outputs are provided with (1) 40-, 80-, and 300-Hz and (2) 40-, 80-, and 600-kHz filtering. The signals are digitized at rates up to 500 kHz and stored in 128K (total system) memory. Foils, gains, and filters are selectable from the control room by a computer.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A bent quartz-crystal spectrometer of the Johann type with a spectral resolution of λ/Δλ= 10000–25000 is used on the Tokamak Fusion Test Reactor (TFTR) to determine central plasma parameters from the spectra of helium-like and lithium-like metal impurity ions (Ti, Cr, Fe, and Ni). The spectra are observed along a central radial chord and are recorded by a position-sensitive multiwire proportional counter with a spatial resolution of 250 μ. Standard delay-line time-difference readout is employed. The data are histogrammed and stored in 64 K of memory providing 128 time groups of 512-channel spectra. The central ion temperature and the toroidal plasma rotation are inferred from the Doppler broadening and Doppler shift of the Kα lines. The central electron temperature, the distribution of ionization states, and dielectronic recombination rates are obtained from satellite-to-resonance line ratios. The performance of the spectrometer is demonstrated by measurements of the Ti xxi Kα radiation.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 123 (1994), S. 0 
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract Eikenella corrodens isolates from periodontally healthy subjects and adult periodontitis patients were compared for their ability to produce a range of potential virulence factors. All were positive for proline aminopeptidase, thiol-dependent haemolysin and esterase activities. Low or negative activities were found against casein, phospholipid, lipid, collagen, aminophosphate, phosphate under acid or alkaline conditions, and eleven other amino acid substrates tested. In oral infections, the haemolytic activity of E. corrodens could be amplified in the reduced environment of the periodontal pocket and damage host cells. Proline aminopeptidase may act against proline residues in collage, immunoglobulins and complement proteins.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Bradford : Emerald
    Industrial robot 32 (2005), S. 444-448 
    ISSN: 0143-991X
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Purpose - Aims to collate and analyse data relating to the sales and installations of industrial robots in the UK for the preceding year and, by comparison with data from previous years, identify market trends. Design/methodology/approach - Data has been collected by the annual survey of UK robot sales and installations conducted by the British Automation and Robotics Association. Findings - The key statistics for 2004 are as follows: a total of 785 units installed; total installations to date (from 1978) are 21,744 units adjusted to 14,176 to allow for International Federation of Robotics 12-year retirement rule; the automotive sector remains dominant but dropped 79 per cent from 2003 to 458 units; the non-automotive sector grew 11 per cent from 2003 with 327 units installed; significant growth in three sectors are: plastics and rubber 46 per cent; construction 85 per cent; and pharmaceuticals 95 per cent. Arc and spot welding installations reduced by 45 per cent, however, spot welding remains dominant application; growth of 80 per cent in "Dispensing" applications; six-axis robots account for majority of the market; significant growth in seven-axis robots; majority of installations fall between £10 and 30?k cost classification highlighting a price drop from 2003; robots originating from EU decreased by 145 per cent; and robots originating from Japan increased by 8 per cent. Originality/value - The study identifies current trends in the UK industrial robot market in terms of factors such as industrial sector, application, robot type/structure and cost. By relating the data to the economic and industrial conditions prevalent in the UK this will provide a useful insight for robot application and development for both end-users and vendors.
    Type of Medium: Electronic Resource
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