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  • 1
    ISSN: 1432-0428
    Keywords: Calcium ; EDTA ; glucose tolerance ; insulin ; uraemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of calcium infusion on the intravenous glucose tolerance was tested in hypocalcaemic patients suffering from renal insufficiency. It was shown that the delayed glucose disappearance rate in uraemics could be improved (p 〈 0.005) by the infusion of calcium gluconolactobionate despite the fact that the serum concentrations of potassium, urea nitrogen, and the blood pH were not altered. The basal insulin concentration was significantly depressed by the calcium infusion (p 〈 0.02). The serum calcium concentration was significantly correlated to the glucose assimilation coefficient in the uraemic patients (p 〈 0.01). — 3 hypocalcaemic patients without renal failure had a normal glucose tolerance and a normalization of the serum calcium concentration had no discernable effect. — A slight but significant decrease of the serum calcium concentration (p 〈 0.01) by EDTA-Na2 in normocalcaemic patients did not change the intravenous glucose tolerance. — It is concluded that hypocalcaemia may be one of the causes for the abnormal glucose tolerance in chronic renal failure.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0428
    Keywords: Key words ; Glucose ; fructose ; insulin ; isolated fat cells ; re-esterification of free fatty acids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In isolated human fat cells of the greater omentum and the mammary gland, the effect of glucose, fructose, and/or insulin was tested on the re-esterification rate of FFA measured by the balance method. It could be shown that in the absence of glucose no re-esterification activity was demonstrable. Glucose alone or fructose alone stimulated the re-esterification of FFA dose-dependently in isolated fat cells of the greater omentum, and to a minor degree in fat cells of the mammary gland. Insulin had no effect on the re-esterification rate of FFA in the presence or absence of glucose or fructose, whereas it significantly stimulated the incorporation of glucose-C into CO2 and lipids. It is concluded that the re-esterification of FFA in human adipose tissue, at least in vitro, is mainly controlled by glucose without need for insulin.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 13 (1966), S. 378-381 
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 20 (1970), S. 337-349 
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wird über eine Patientin mit einer akuten myeloischen Leukämie berichtet, die im Knochenmark überwiegend atypische Myeloblasten aufwies. Im Gegensatz dazu fanden sich im peripheren Blut eine große Anzahl ebenfalls atypischer “Neutrophiler” sowie eine beträchtliche Zahl monozytenähnlicher Zellen, die wirals Zwischenformen zwischen den atypischen Myeloblasten und den pathologischen Neutrophilen auffassen. Die pathologischen “Neutrophilen” zeigen ein ungewöhnliches zytochemisches Muster, in dem der größte Teil dieser Zellen keine Sudanschwarz-B-positiven Lipide sowie kaum Peroxydase-Naphthol-AS-D-Cloroacetat-Esterase-Aktivität aufweist. Diese drei zytochemischen Reaktionen geben normalerweise eine starke positive Reaktion in den neutrophilen Granulozyten. Außerdem wurde eine atypische Werteinteilung sowohl der alkalischen Phosphatase als auch der Naphthylamidase festgestellt. Die monozytenähnlichen Zwischenformen unterscheiden sich deutlich in ihrem zytochemischen Muster von normalen Monozyten und gleichen den atypischen neutrophilen Zellen. Diese zytochemischen Befunde stützen die Ansicht, daß es bei der Patientin zu einer Ausreifung der Myeloblasten über ein monozytenähnliches Zwischenstadium zu atypischen “neutrophilen” Granulozyten gekommen ist. Trotz der hohen Zahl “neutrophiler” Granulozyten im peripheren Blut (10 350/mm3) wurden in den blutbildenden Organen nur wenig typische neutrophile Vorstufen mit einem normalen Enzymmuster festgestellt.
    Notes: Summary A case of a patient is presented, who suffered from acute leukemia, showing predominantly atypical myeloblasts in the bone marrow. In contrast, a high amount of atypical “neutrophils” were present in the peripheral blood, as well as there was a conspicuous number of monocyte-like intermediate forms between the myeloblasts and the atypical segmented “neutrophils.” The cytochemical pattern of the “Neutrophils” was highly atypical, the main part being devoid of sudanblack B-positive lipids, as well as of peroxidase and chloroacylesterase activity, which characteristically are present in large amounts in the neutrophil granulocytes. Moreover, atypical distribution of alkaline phosphatase and naphthylamidase activities were encountered in these cells. The intermediate or transitional cells exhibited a cytochemical pattern different from that of normal blood monocytes, but corresponding to that of the atypical neutrophils. Thus, the assumption of a direct maturation way from myeloblasts to “paraneutrophils” with mononuclear, monocyte-like intermediate stages was supported by the results of cytochemical investigations. In contrast to the elevated number of neutrophils in the peripheral blood (10 350/mm3) very rare normal neutrophil precursors with typical cytochemical pattern were encountered in the haematopoietic organs.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 22 (1971), S. 144-147 
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 17 (1968), S. 45-47 
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 19 (1969), S. 437-439 
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 23 (1971), S. 42-46 
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The immunocytologically determined number of gamma-g-containing peripheral lymphocytes was compared in diseases showing an increased appearance of lymphatic irritation cells in the peripheral blood. Patients suffering from mononucleosis infectiosa hepatitis epidemica, measles and rubella showed an increase in both cell populations. Patients suffering from Morbus Hodgkin showed an isolated increase of3H-tymidine labelled lymphocytes One after another did at first the3H-thymidine labelled cells reach the highest values, then the gamma-g-containing cells. On direct coordination it could be demonstrated that the IgG-containing cells where up to one fifth3H-thymidine labelled, and consequently should be separable. A greater amount of lymphoid cells, comparable to the amount of IgG-containing cells, showed a considerable quantity of ergastoplasm in the electronmicroscopic classification.
    Notes: Zusammenfassung Bei Erkrankungen mit vermehrtem Auftreten lymphatischer Reizformen im peripheren Blut wurde die immunzytologisch bestimmte Zahl gamma-Ghaltiger peripherer Lymphozyten mit der von3H-Thymidin-markierten Lymphozyten verglichen. Bei Patienten mit Mononucleosis infectiosa Hepatitis epidemica, Morbilli und Rubeolen ergab sich eine Zunahme beider Zellpopulationen, bei Patienten mit Morbus Hodgkin wurde eine isolierte Vermehrung der3H-Thymidin-markierten Lymphozyten beobachtet. Im zeitlichen Ablauf erreichten zuerst die3H-Thymidin-markierten, dann die gamma-G-haltigen Zellen die höchsten Werte. Bei der direkten Zuordnung zeigte sich, daß bis zu einem Fünftel der IgG-haltigen Zellen3H-Thymidin-markiert waren und somit teilungsfähig, sein dürften. Eine der Zahl der IgG-haltigen Lymphozyten vergleichbare, wenn auch etwas größere Anzahl lymphoider Zellen wies bei der elektronenmikroskopischen Klassifizierung vermehrt Ergastoplasma auf.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 29 (1974), S. 224-226 
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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