Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Environmental geology 20 (1992), S. 43-55 
    ISSN: 1432-0495
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract The sulfate pollution in an agriculturally used watershed has been investigated with respect to the transport in the saturated zone and the development of sulfate in the unsaturated zone. Besides of other sources such as acid wet and dry deposition or sulfate input by agricultural activities, most of the sulfate originates from oxidation of pyrite by either NO3 or O2. High sulfate concentrations coincided with high nitrate leaching caused by plowing of former grassland or by vegetable crop residues and with former wet lands that have become dry. By using soil water concentration data and maps showing the extension of former wetlands and grassland as well as agricultural land use, it was possible to delineate regions of high sulfate input. The transport of sulfate in the aquifer was analyzed with a modified version of the USGS MOC model, which takes into account the nonlinearity of the underlying equation describing unconfined groundwater flow. The calibration of the transport model showed good agreement between the estimated and modeled sulfate input rates. A prediction of future sulfate concentrations in the aquifer was feasible by using “worst-case” parameters.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 46 (1968), S. 49-51 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary A case of ectopic ACTH syndrome is reported presenting with hypercorticism and pronounced hypokalemic alkalosis in a woman aged 55 y. with metastatic cancer of the pancreas. The failure to show a significant difference of plasma ACTH-levels from bulbus superior venae jugularis resp. femoral vein supported the clinical assumption of non pituitary origin of elevated plasma ACTH.
    Notes: Zusammenfassung Es wird über einen Fall von ektopischem ACTH-Syndrom mit Hypercortizismus und hypokaliämischer Alkalose bei einem metastasierten Pankreas-Carcinom berichtet. Das Fehlen einer Differenz zwischen den ACTH-Spiegeln im Plasma aus dem Bulbus cranialis venae jugularis und aus der Vena femoralis unterstützte die Annahme einer nicht hypophysären Herkunft der erhöhten ACTH-Spiegel.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 51 (1973), S. 143-144 
    ISSN: 1432-1440
    Keywords: Intestinal alkaline phosphatase ; bone alkaline phosphatase ; hyperthyroidism ; Alkalische Dünndarmphosphatasen ; alkalische Knochenphosphatasen ; Hyperthyreose
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Parallel zu tierexperimentellen Befunden, daß Thyroxingaben zu einer erhöhten Enzymkonzentration alkalischer Phosphatasen im Dünndarmgewebe führen, konnte im Serum von 50 hyperthyreoten Patienten eine Vermehrung intestinaler alkalischer Phosphatasen nachgewiesen werden. Damit tragen neben der deutlichen Zunahme von Isoenzymen ossären Ursprungs als Folge reaktiv gesteigerter Osteoblastentätigkeit auch intestinale alkalische Phosphatasen zu der bei einer Hyperthyreose häufig zu findenden Erhöhung der Serumgesamtaktivität bei. Die angeführten Befunde sollten daher für die differentialdiagnostische Wertung des klinisch-chemischen Parameters „Gesamtaktivität der alkalischen Phosphatase im Serum“ bei der Hyperthyreose berücksichtigt werden.
    Notes: Summary According to experimental results showing increased alkaline phosphatase concentrations in the small intestine of hyperthyroid rats, elevated intestinal alkaline phosphatase serum levels were observed in hyperthyroid patients with normal liver function. Therefore, an elevation of total serum alkaline phosphatase activity in hyperthyroidism is not only due to the main increase of bone phosphatase activity but also to an increase of intestinal alkaline phosphatase activity.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 45 (1967), S. 323-324 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary A group of clinically euthyroid obese patients was found to have significantly lower PBI-values (4,47 γ-%) than controls (5,09 γ-%). Binding of triiodothyronine-125I to serum proteins as estimated by dextran gel filtration was significantly increased in the obese group (87,64 vs. 84,98%).
    Notes: Zusammenfassung Das proteingebundene Jod im Serum wurde bei einer Gruppe von adipösen Patienten im Mittel signifikant vermindert gegenüber dem Mittelwert eines Normalkollektivs gefunden. Die Bindung von Trijodthyronin-125Jod an Serumproteine war bei Adipositas signifikant erhöht.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The myocardial extraction of acetoacetate and β-hydroxybutyrate was determined in 55 metabolically normal patients during diagnostic heart catheterizations. In order to obtain a complete insight into the substrate supply of the myocardium, arterio-coronary-venous differences of glucose, lactate, pyruvate, non esterified fatty acids, amino acids and oxygen were also measured. From the considerably varying arterial concentrations of acetoacetate (7,2±0,66 µMol/100) and β-hydroxybutyrate (21,3±2,6 µMol/100) the human heart muscle extracts an average of 50% acetoacetate (3,6±0,36 µMol/100) and 35,2% β-hydroxybutyrate (7,5±1,2 µMol/100). Both substrates showed a statistically significant correlation between arterial concentration and myocardial extraction. The β-hydroxybutyrate/acetoacetate quotient was found to be 2,87±0,25 in the arterial and 3,69±0,31 in the coronaryvenous blood. Although a high percentage of the arterial level of acetoacetate is extracted by the heart, this substrate accounts for only 2,6±0,3% of the total oxydative myocardial metabolism. The value for β-hydroxybutyrate at 6,0±1,0% is considerably higher, thus obtaining an oxygen extraction ratio of 8,6% for the total ketone-bodies. The other substrates involved in the myocardial metabolism showed oxygen extraction ratios similar to those previously reported by our group: glucose 14,5±1,9%, lactate 12,9±1,1%, pyruvate 1,0±0,1%, non esterified fatty acids 69,7±3,0%. With higher arterial levels of ketone-bodies an increase of their oxygen extraction ratio was found, whereas the uptake of carbohydrates was proportionally decreased. The percentual extraction of non esterified fatty acids did not change. These results indicate that the myocardium oxidizes ketonebodies in preference to carbohydrates. The redox-potentials of the β-hydroxybutyrate/acetoacetate and the lactate/pyruvate systems are changed across the heart in an opposite way. The β-hydroxybutyrate/acetoacetate system becomes more negative (ΔE=−3,1±0,6 mV), the lactate/pyruvate system tends to be slightly positive (ΔE=+0,9±0,63 mV).
    Notes: Zusammenfassung Das Verhalten von Acetacetat und β-Hydroxybutyrat im Stoffwechsel des menschlichen Herzens wurde im Rahmen diagnostischer Herzkatheterisationen an 55 stoffwechselgesunden Patienten untersucht. Außerdem erfolgte die Bestimmung der arterio-coronarvenösen Differenzen für Glucose, Lactat, Pyruvat, nicht veresterten Fettsäuren, Aminosäuren und Sauerstoff, um einen vollständigen Einblick in die Substratversorgung des Myokards zu erhalten. Bei physiologisch stark schwankenden arteriellen Konzentrationen von Acetacetat (7,2±0,66 µMol/100) und β-Hydroxybutyrat (21,3±2,6 µMol/100) extrahiert der Herzmuskel vom Angebot durchschnittlich 50% Acetacetat (3,6±0,36 µMol/100) und 35,2% β-Hydroxybutyrat (7,5±1,2 µMol/100). Für beide Substrate konnte zwischen arterieller Konzentration und myokardialer Extraktion eine statistisch gesicherte Abhängigkeit nachgewiesen werden. Der Quotient β-Hydroxybutyrat/Acetacetat beträgt arteriell 2,87±0,25 und coronarvenös 3,69±0,31. Der Anteil von Acetacetat am oxydativen Stoff-wechsel des menschlichen Herzens erreicht trotz hoher prozentualer Extraktion nur 2,6±0,3%. Der Wert für β-Hydroxybutyrat liegt mit 6,0±1,0% wesentlich höher, so daß sich für die Gesamtketonkörper ein Sauerstoffextraktionsquotient von 8,6% ergibt. Für die übrigen am Myokardstoffwechsel beteiligten Substrate errechnen sich Sauerstoffextraktionsquotienten, die in den von uns bereits früher angegebenen Bereich fallen: Glucose 14,5±1,9%, Lactat 12,9±1,1%, Pyruvat 1,0±0,1%, nicht veresterte Fettsäuren 69,7±3,0%. Bei überdurchschnittlich hohen arteriellen Ketonkörperkonzentrationen nimmt der Anteil der Ketonkörper am gesamten oxydativen Stoffwechsel des Herzens beträchtlich zu, während die Kohlenhydrate in etwa gleicher Größenordnung abnehmen. Die nicht veresterten Fettsäuren zeigen keine Änderung ihrer prozentualen Extraktion. Die Ketonkörper stellen somit gegenüber den Kohlenhydraten ein vom Herzmuskel bevorzugtes Substrat dar. Die Redoxpotentiale der Substratpaare ß-Hydroxybutyrat/Acetacetat und Lactat/Pyruvat werden bei der Herzmuskelpassage im Prinzip in gegensätzlicher Weise verändert, und zwar erfährt das β-Hydroxybutyrat/Acetacetat-System eine Negativierung (ΔE=−3,1±0,6 mV) und das Lactat/Pyruvat-System eine angedeutete Positivierung (ΔE=+0,9±0,63 mV).
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    ISSN: 1432-1440
    Keywords: Angiotensin-converting enzyme inhibitors ; Cilazapril ; Furosemide ; Natriuresis ; Antinatriuresis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The goal of this study was to quantitate the effect of angiotensin-converting enzyme inhibition on renal sodium handling after furosemide injection. The study was carried out on low and normal salt intake to assess potential interaction with salt balance. Eighteen healthy normotensive volunteers were examined in a double placebo-controlled parallel group design. Subjects were randomly put on either low-salt (20 mmol/day) or normal-salt (110 mmol/day) diet. In either arm of the diet volunteers were first treated orally with placebo for 1 week and subsequently with 2.5 mg/day of the angiotensin-converting enzyme inhibitor cilazapril for another 1 week. Cumulative 24-h urinary sodium excretion was measured on the 6th day of the respective week after sham injection and on the 7th day after injection of 40 mg furosemide. Compared to pretreatment with placebo, pretreatment with cilazapril resulted in a higher cumulative sodium excretion after furosemide injection (day 7) than after the sham injection (day 6) on both salt intakes. The difference in natriuresis (cilazapril versus placebo) was evident 2 and 3 h after injection of furosemide. Neither the time of onset nor the magnitude of antinatriuresis were affected by cilazapril. Following furosemide angiotensin II increased significantly even after cilazapril pretreatment. Cilazapril tended to reduce urinary furosemide excretion. At any given urinary furosemide concentration, the increment in urinary sodium excretion was significantly greater with cilazapril irrespective of salt intake. The study shows that (a) cilazapril increases furosemide-induced natriuresis irrespective of salt intake, (b) antinatriuresis is not affected by cilazapril, and (c) angiotensin II levels rise after furosemide on cilazapril in therapeutic doses.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Medical microbiology and immunology 134 (1952), S. 549-564 
    ISSN: 1432-1831
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Medical microbiology and immunology 138 (1954), S. 535-541 
    ISSN: 1432-1831
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Die tuberculostatischen Dosen (t.s.D.) für Streptomycin∶Conteben ∶PAS∶Neoteben verhalten sich wie 100∶10∶5∶1. Unter 34 TbB-Stämmen sind nur 8, deren Empfindlichkeit gegen 4, 3 oder 2 dieser Tuberculostatica der des Teststammes H 37 Rv entspricht. Die höchste Quote resistenter Stämme wurde gegenüber Neoteben mit 52% gefunden, es folgen PAS mit 31%, Conteben mit 27% und Streptomycin mit 18%. Verminderte Empfindlichkeit=t.s.D. höher als bei Teststamm H 37 Rv zeigten gegenüber Conteben 73%, Neoteben 67%, Streptomycin 52% und PAS 38% der Stämme. Resistenz oder verminderte Empfindlichkeit gegenüber Streptomycin tritt fast nur gemeinsam mit diesen Erscheinungen gegenüber anderen Tuberculostatica auf, dagegen wird verminderte Empfindlichkeit oder Resistenz gegenüber Neoteben in der Mehrzahl der Fälle isoliert gefunden. Resistenzsteigerung in vitro durch Abimpfen der resistentesten Kolonie und Weitertesten in ein- bis zweimaliger Folge erfolgt bei Conteben in steigender Erhöhung bis zu einem Maximum, bei Neoteben wird bereits bei der ersten Weiterimpfung das Maximum der Resistenz erreicht. Dies wird als adaptationsähnliche Erscheinung bei Conteben angesehen, die auszubilden die TbB-Stämme bei Neoteben auf Grund dessen relativer Neuheit in der Behandlung noch nicht imstande waren.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Biological cybernetics 54 (1986), S. 313-317 
    ISSN: 1432-0770
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Computer Science , Physics
    Notes: Abstract Experiments by Schiller et al. have suggested that non-directional edge-specific simple cells are constructed from two directionally selective subunits with opposite preferred direction. This hierarchical notion was based on the fact that the responses of such units to edges moving in opposite directions are spatially displaced with respect to each other. An alternative explanation of the observed response separation is the delay between the responses of the center and surround mechanisms at the retinal level. Measurements of the response separation as a function of stimulus speed support this explanation and argues against the hierarchical notion of Schiller et al.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...