ISSN:
1432-1041
Schlagwort(e):
dimethicone
;
cytoprotection
;
gastric lesions
;
potential difference
;
bile salts
;
healthy volunteers
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Chemie und Pharmazie
,
Medizin
Notizen:
Summary The gastric potential difference (PD) was measured in ten healthy volunteers after sodium taurocholate intake. This bile salt was given after treatment with dimethicone or placebo in a cross-over design study. With dimethicone the fall in PD was lower (16.1 vs. 24.8 mV,) and shorter (32.5 vs. 51.0 min) than with the placebo. Our result suggests that the silicone can prevent the formation of the gastric lesions induced by bile salts.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00558299
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