ISSN:
1420-9071
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Medizin
Notizen:
Summary In the end-stage of progressive alloxan diabetes of the rabbit we have been able to overcome the acute pyruvic acidosis by the use of phosphorylated vitamin B1 (cocarboxylase) together with vitamin B2, while it is impossible to cure the endogen hyperpyruviæmia with simple vitamin B1. The superiority of the coferment over the vitamin, which is only effective at the beginning of the decompensation, implies the existence of a disturbance in the phosphorylation during the crisis of diabetic metabolism. We have been successful in preventing the inevitable death in coma of diabetic rabbits by doses of cocarboxylase + riboflavin, and we were able to keep them alive by continuous doses of insulin together with vitamin B1 and B2.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF02153878
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