ISSN:
1432-0584
Schlagwort(e):
Walker carcinosarcoma
;
3H-TdR-uptake
;
In vitro test
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Medizin
Notizen:
Summary In 36 Walker-ascites-carcinosarcoma bearing rats the reduction of 3H-TdR-incorporation into tumor cells after cytotoxic treatment as an potential prognostic factor for efficacy of chemotherapy was tested. Twelve rats each were i.p. treated with 1 mg/kg bw. DDP resp. 0.8 mg/kg bw. Adriamycin. Twelve rats were injected with 0.2 mg phys. NaCl and served as control. Survival of rats served as criterion of therapeutic efficacy. There was a significant correlation between reduction of 3H-TdR-uptake in tumor cells after cytotoxic therapy and survival.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00320469
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