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  • Electronic Resource  (5)
  • 1985-1989  (4)
  • 1970-1974  (1)
  • 1900-1904
  • 1987  (4)
  • 1973  (1)
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  • Electronic Resource  (5)
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  • 1985-1989  (4)
  • 1970-1974  (1)
  • 1900-1904
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  • 1
    Electronic Resource
    Electronic Resource
    Antiallergic activity of loratadine, a non-sedating antihistamine (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 42 (1987), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Loratadine is a new non-sedating antihistamine. The present studies compared loratadine and terfenadine, another non-sedating antihistamine, for their ability to inhibit the bronchial response to histamine and other autacoids which have been implicated as contributing to the symptoms of an allergic reaction. In addition, the two antihistamines were evaluated in models of immunologically mediated allergic reactions. Loratadine is a more potent inhibitor of histamine-induced bronchospasm in guinea pigs than is terfenadine. Both antihistamines exhibit marked antiserotonin activity at doses 10 times their antihistamine ED50 values. In contrast, loratadine and terfenadine produce little or no inhibition of the bronchial responses to methacholine, leukotriene C4 or platelet-activating factor. An allergic bronchospasm in guinea pigs is inhibited by loratadine (ED50= 0.40 mg/kg, p.o.) and terfenadine (ED50= 1.7 mg/kg, p.o.). The bronchospasm associated with allergic anaphylaxis in rats is significantly inhibited by 10 mg/kg, p.o. loratadine and 30 mg/kg, p.o. terfenadine. Loratadine exhibits antiallergy activity in vitro. At micromolar concentrations, loratadine inhibits the release of histamine from Con A and A23187-stimulated rat peritoneal mast cells and the release of histamine and leukotrine C4 from a Con A-stimulated cloned murine mast cell line
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1398-9995.1987.tb02188.x
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  • 2
    Electronic Resource
    Electronic Resource
    The regulation of feeding in Locusta migratoria: Internal inhibitory mechanisms (1973)
    Springer
    Entomologia experimentalis et applicata 16 (1973), S. 329-342 
    Details
    ISSN: 1570-7458
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Zusammenfassung Alle Hauptnerven des Mund- und Rachennervensystems wurden kontrolliert reseziert. Erst wenn die rückwärtigen Rachennerven zerschnitten werden, nehmen die Insekten wesentlich mehr Nahrung zu sich. Solche Insekten versuchen längere Zeit zu fressen. Wenn sich während des Fressens der Vorderdarm füllt, wird keine Nahrung an den Mitteldarm weitergegeben und sein Vorderende ist der letzte Teil, der sich vollständig ausdehnt. Nach Durchtrennung der rückwärtigen Rachennerven sind alle Teile des Vorderdarms offen-sichtlich mehr gedehnt. Eine solche erhöhte Nahrungsaufnahme tritt aber nicht ein, wenn die Nahrung relativ ungünstig ist. Das Abbinden des Kropfes verursacht beim nachträglichen Fressen keine übermäßige Ausdehnung des Vorderteiles. Die Nahrungsaufnahme hat keinen Unterschied im Körpervolumen zur Folge und das Durchtrennen des ventralen Nervenstranges bleibt ohne Einfluß auf die nachträglich aufgenommenen Nahrungsmengen. Das vergrößerte Darmvolumen wird durch Kollaps des Luftsackes kompensiert.
    Notes: Abstract During the course of a meal by insects with an empty gut, food is held in the foregut and the midgut remains empty. The last part of the foregut to fill is the extreme anterior end of the crop, and stretch receptors in this region control the amount eaten. Cutting the posterior pharyngeal nerves isolates these receptors from the frontal garglion and results in hyperphagia pharyngeal nerves isolates these receptors from the frontal garglion and results in hyperphagia during one meal. On unfavourable food, when smaller amounts are eaten, distension of the foregut is not involved in regulating meal size. Feedback from receptors in the body wall is not important in regulating meal size; most of the increase in gut volume resulting from feeding is taken up by the collapse of the air sacs so that there is little or no change in the body volume.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00334244
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Secretion and membrane recycling in plant cells: novel intermediary structures visualized in ultrarapidly frozen sycamore and carrot suspension-culture cells (1987)
    Springer
    Planta 171 (1987), S. 43-57 
    Details
    ISSN: 1432-2048
    Keywords: Acer ; Daucus ; Cell culture ; Freeze-fracture (rapid freezing) ; Membrane recycling ; Plasma membrane ; Secretion (vesicle-mediated)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Freeze-fracture electron microscopy of propane-jet-frozen samples has been employed to investigate vesicle-mediated secretion and membrane recycling events in carrot (Daucus carota L.) and sycamore maple (Acer pseudoplatanus L.) suspension-culture cells. Stabilization of the cells by means of ultrarapid freezing has enabled us to preserve the cells in a turgid state and to visualize new intermediate membrane configurations related to these events. Indeed, many of the observed membrane configurations, such as flattened membrane vesicles with slit-shaped membrane fusion sites and horseshoe-shaped membrane infoldings, appear to result from the action of turgor forces on the plasma membrane. Individual cells exhibited great variations in numbers and types of membrane configurations postulated to be related to secretion and membrane-recycling events. In the majority of cells, the different membrane profiles displayed a patchy distribution, and within each patch the membrane configurations tended to be of the same stage. This result indicates that secretory events are triggered in domains measuring from 0.1 to about 10 μm in diameter. Based on an extensive analysis of the different membrane configurations seen in our samples, we have formulated the following model of vesicle-mediated secretion in plant cells: Fusion of a secretory vesicle with the plasma membrane leads to the formation of a single, narrow-necked pore that increases in diameter up to about 60 nm. During discharge, the vesicle is flattened, forming a disc-shaped structure perpendicular to the plane of the plasma membrane. As the vesicle is flattened, the pore is converted to a slit, the maximum length of which coincides with the diameter of the flattened vesicle. The flattened vesicle then tips over and concomitantly the plasma-membrane slit becomes curved into a horseshoe-shaped configuration as it extends along the outer margins of the tipped-over vesicle. Some coated pits are present interspersed between the above-mentioned structures, but their numbers appear insufficient to account for an exclusively endocytotic mechanism of membrane recycling. Instead, our micrographs are more consistent with a mixed mode of recycling of membrane components to the cortical endoplamic reticulum and to Golgi cisternae that involves both internalization of membrane by endocytosis and of individual lippid molecules by unknown mechanisms (lipid exchange proteins?). To this end, overall flattening out of the horseshoe-shaped membrane infoldings is accompanied by a retraction and reduction in size of their central, tongue-like structure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00395066
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  • 4
    Electronic Resource
    Electronic Resource
    Search for superdeformation in180Os (1987)
    Springer
    The European physical journal 328 (1987), S. 379-380 
    Details
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Two-dimensional γ-ray energy correlations have been measured at high spins in1800s with the TESSA2 spectrometer. The Eγ − Eγcorrelation matrix displays ridges characteristic of rotational bands with different energy separations of 96± and 72± keV for the energy regions of 660 to 840 keV and 975 to 1170 keV, respectively. The separation of these ridges remains constant in both energy regions. The dynamical moments of inertia are θ(2) =83±3 and 111±5 ħ2/MeV, respectively. The latter value suggests superdeformation in1800s with an axis ratio c/a=1.76 (β2 ≅0.64) at high spins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01290507
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  • 5
    Electronic Resource
    Electronic Resource
    Functional response of pacific damsel bug,Nabis kinbergii [Hemiptera: Nabidae] (1987)
    Springer
    BioControl 32 (1987), S. 303-309 
    Details
    ISSN: 1573-8248
    Keywords: Pacific damsel bug ; nabid ; functional response ; Punaise du Pacifique ; nabide ; réponse fonctionnelle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Description / Table of Contents: Résumé La punaise,Nabis kinbergii Reuter est rencontrée communément dans les champs de luzerne à la fin de l'été et durant l'automne en Nouvelle Zélande. Son potentiel en tant que prédateur des espèces communes d'insectes ravageurs n'a pas encore été étudié. Ce travail rend compte de la roponse fonctionnelle des femelles adultes et des 5e stades larvaires de cette punaise vis-à-vis de deux espèces proies, le miride:Sidnia kinbergi (Stal) et le puceron du pois:Acyrtosiphon pisum (Harris). Une équation deHolling (1959) de type II définit bien la réponse fonctionnelle de ce prédateur sauf lorsque les 5e stades n'ont que des nymphes du Miride pour proie. Cette punaise,Nabis kinbergii manifeste des réponses identiques à celles d'un autreNabidae: Reduviolus americoferus (L.).
    Notes: Abstract The functional responses of adult and 5th instar Pacific damsel bug,Nabis kinbergii Reuter were determined under laboratory conditions using Australian crop mirid,Sidnia kinbergi (Stal), and pea aphid,Acyrthosiphon pisum (Harris) as prey.Holling's (1959) type II equation was found to adequately define the functional response of this predator except when 5th instar nymphs were provided with Australian crop mirid as prey. In this instance, a type III response was found.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02373255
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    Paper (German National Licenses)
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