ISSN:
1573-0778
Keywords:
deletion 7q
;
met oncogene
;
myelofibrosis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
,
Process Engineering, Biotechnology, Nutrition Technology
Notes:
Abstract The met oncogene is the normal counterpart of a chemically-induced transforming gene. The chromosomal localization of met is 7q21–31. In a patient with myelofibrosis and an interstitial deletion on 7q, we demonstrate that a Taq I polymorphism for the met oncogene is lost in the neoplastic cells, thus indicating that the deletion occuring in the long arm of chromosome 7 involves the met locus.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00351120
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