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  • 1990-1994
  • 1985-1989  (3)
  • 1965-1969
  • 1988  (3)
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  • 1990-1994
  • 1985-1989  (3)
  • 1965-1969
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  • 1
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    Unbekannt
    The Development of Criminology in Britain 1948-1960 (1988)
    London : Periodicals Archive Online (PAO)
    British Journal of Criminology, Delinquency and Deviant Social Behaviour. 28:2 (1988:Spring) 165 
    Details
    ISSN: 0007-0955
    Thema: Rechtswissenschaft
    Notizen: A HISTORY OF BRITISH CRIMINOLOGY
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:4065-1988-028-02-000004
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Temperature-sensitive mutants of mouse hepatitis virus type 3 (MHV-3): isolation, biochemical and genetic characterization (1988)
    Springer
    Archives of virology 100 (1988), S. 147-160 
    Details
    ISSN: 1432-8798
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Mouse hepatitis virus 3 (MHV-3) is highly hepatotropic in sensitive mice. Temperature-sensitive mutants (ts mutants) induced by N-methyl-N′-nitrosoguanidine and 5-fluorouracil were isolated. Twelve mutants which were able to induce the formation of syncytia at 33°C but not at the restrictive temperature (39.5°C) were selected for detailed study. No viral RNA synthesis was detected after infection at the restrictive temperature with six of the mutants (RNA−) whereas six others were RNA+, although they displayed RNA synthesis which was generally reduced. No differences have been detected in the size of the genome or the viral-intracellular RNA species found in wild type virus or ts mutant infected cells at permissive temperature. The pattern of virus-induced proteins analyzed after immunoprecipitation by SDS-PAGE was similar in wild type virus and RNA+ mutant infected cells at 39.5°C. Complementation experiments between ts mutants enabled us to distinguish five groups. Three of the groups contained RNA− mutants and two of them RNA+. Plaques made by mutants in one group displayed characteristic features that distinguished them from the wild type.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01487679
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  • 3
    Digitale Medien
    Digitale Medien
    Respiratory symptoms and pulmonary function in 871 miners according to Pi phenotype: A longitudinal study (1988)
    Springer
    European journal of epidemiology 4 (1988), S. 39-44 
    Details
    ISSN: 1573-7284
    Schlagwort(e): Epidemiology ; Occupational pathology ; Chronic bronchitis Iron miners ; Protease inhibitor (Pi) phenotype
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Pi phenotype was determined and α1 protease inhibitor (α1Pi) was measured in 871 iron-ore miners examined twice at five years interval. A questionnaire on respiratory symptoms was administered and lung function tests: spirometry (VC, FEV1.0), measurements of the residual volume (RV/TLC) and of the CO diffusion (FuCO), were carried out by the same medical and technical team, using the same apparatus. There were no differences in age, lenght of employment or smoking habits among the three Pi Phenotype groups: M (90:03%), MS (7.1%), MZ (2.8%). The prevalence of clinical symptoms at the initial survey and the incidence of symptoms between the 2 surveys were not related to Pi Phenotype groups. However a significantly steeper decline of FEV1.0/VC was observed in the α1Pi partially deficient groups MS and MZ (−3.9%) compared with the non-deficient group (−1.8%). No significant difference was observed for VC, RV /TLC and FuCO. This finding suggests that an intermediate deficiency of α1Pi may be related to a slight but statistically significant impairment of a lung function in occupational conditions.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00152690
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