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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Langmuir 11 (1995), S. 186-190 
    ISSN: 1520-5827
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the American Water Resources Association 31 (1995), S. 0 
    ISSN: 1752-1688
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Notes: : During the latter part of the 19th century and the early part of the 20th century, a major cycle of erosion, arroyo cutting, and gullying occurred in the southwestern United States. Since this erosion cycle began, many projects to control erosion, such as the Civilian Conservation Corps projects in the 1930s, were initiated. However, in the Southwestern United States few studies have documented the effect of these structures in reducing erosion or their effect on gully systems. As part of a watershed rehabilitation project on the Zuni Reservation, New Mexico, 47 structures made either of earth or rocks and 23 rock and brush structures were assessed. Sixty percent of the 47 earth or rock structures have breached and relative to dam height, 65 percent of 47 structures are more than 50 percent silted. Of the 23 rock and brush structures, 22 percent have breached or are close to breaching. Reasons for breaching of all structural types may be piping, scour immediately below the structures, large runoff and large drainage area, poor maintenance, headcutting, and active arroyo deepening and widening. In most cases, documentation does not exist on structure design, the specific purpose for a structure, or when these structures were built.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Some cases of autosomal-dominant familial amyotrophic lateral sclerosis (FALS) have been associated with mutations in SOD1, the gene that encodes Cu/Zn superoxide dismutase (Cu/Zn SOD). We determined the concentrations (µg of Cu/Zn SOD/mg of total protein), specific activities (U/µg of total protein), and apparent turnover numbers (U/µmol of Cu/Zn SOD) of Cu/Zn SOD in erythrocyte lysates from patients with known SOD1 mutations. We also measured the concentrations and activities of Cu/Zn SOD in FALS patients with no identifiable SOD1 mutations, sporadic ALS (SALS) patients, and patients with other neurologic disorders. The concentration and specific activity of Cu/Zn SOD were decreased in all patients with SOD1 mutations, with mean reductions of 51 and 46%, respectively, relative to controls. In contrast, the apparent turnover number of the enzyme was not altered in these patients. For the six mutations studied, there was no correlation between enzyme concentration or specific activity and disease severity, expressed as either duration of disease or age of onset. No significant alterations in the concentration, specific activity, or apparent turnover number of Cu/Zn SOD were detected in the FALS patients with no identifiable SOD1 mutations, SALS patients, or patients with other neurologic disorders. That Cu/Zn SOD concentration and specific activity are equivalently reduced in erythrocytes from patients with SOD1 mutations suggests that mutant Cu/Zn SOD is unstable in these cells. That concentration and specific activity do not correlate with disease severity suggests that an altered, novel function of the enzyme, rather than reduction of its dismutase activity, may be responsible for the pathogenesis of FALS.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-2072
    Keywords: GM1 ; Haloperidol ; Glutamate synapses ; Perforated PSD ; Striatum ; Dopamine receptors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Haloperidol, a typical antipsychotic drug, causes an increase in the mean percentage of synapses within the striatum containing a discontinuous, or perforated, postsynaptic density (PSD) following 1 month of treatment (Meshul et al. 1994). This effect is not observed with the atypical antipsychotic drug, clozapine, following subchronic administration (Meshul et al. 1992a). This morphological change is also associated with an increase in the density of dopamine D2 receptors. The synapses containing the perforated PSD are asymmetrical and the nerve terminals contain the neurotransmitter, glutamate, as demonstrated by immunocytochemistry. We have also shown that subchronic treatment with haloperidol (0.5 mg/kg per day, 30 days) results in a decrease in the density of glutamate immunoreactivity within asymmetric nerve terminals associated with perforated and non-perforated PSDs (Meshul and Tan 1994). This could be due to an increase in glutamate release, perhaps due to activation of corticostriatal synapses. Agnati et al. (1983a) reported that administration of GM1 ganglioside blocks the increase in dopamine D2 receptors following haloperidol treatment. GM1 has also been shown to attenuate the release of glutamate (Nicoletti et al. 1989). In order to determine if similar treatment with ganglioside could block the haloperidol-induced ultrastructural changes noted above, rats were coadministered GM1 (10 mg/kg per day) and haloperidol (0.5 mg/kg per day) for 30 days. We report that GM1 blocked the haloperidol-induced increase in striatal asymmetric synapses containing a perforated PSD, but had no effect on the increase in dopamine D2 receptors or the decrease in nerve terminal glutamate immunoreactivity. GM1, either alone or co-administered with haloperidol, also caused a small, but significant, increase in the density of all asymmetric synapses within the striatum. It is possible that the effect of GM1 in attenuating the haloperidol-induced change in glutamate synapses with perforated PSDs is primarily postsynaptic, since GM1 did not block the change in density of glutamate immunoreactivity within asymmetric nerve terminals.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Fermilab experiment E735 located at the CO intersection region of the $$\sqrt s = 1.8$$ TeV $$p\bar p$$ collider analysed over 900 Φ→K + K − events. Measured were the transverse momentum spectrum, the correlation between the average transverse momentum 〈pt〉 and the charged particle multiphcityN c , as well as the probability of Φ production per charged track,N Φ /N c , versusN c . We have also made an estinate of the total inclusive cross section for Φ mesons, $$\sigma (p\bar p \to \phi X) = 7.3 \pm 2.2 mb$$ .
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Foundations of physics 25 (1995), S. 1359-1370 
    ISSN: 1572-9516
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Can a value of a physical property be created instantaneously by a distant act of measurement? This paper develops an answer to that question by reconciling ideas expressed by Bohr in 1958 with the “standard” Copenhagen interpretation. The point of view thereby obtained is then applied to recently described correlation experiments of various sorts.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Research in engineering design 7 (1995), S. 67-85 
    ISSN: 1435-6066
    Keywords: Agents ; Conceptual robustness ; Concurrent engineering ; Distributed concurrent engineering ; Distributed decision making
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Technology
    Notes: Abstract This paper develops a robust and distributed decision-making procedure for mathematically modeling and computationally supporting simultaneous decision-making by members of an engineering team. The procedure (1) treats variations in the design posed by other members of the design team asconceptual noise; (2) incorporates such noise factors into conceptually robust decision-making; (3) provides preference information to other team members on the variables they control; and (4) determines whether to execute the conceptually robust decision or to wait for further design certainty. While Changet al. (1994) extended Taguchi's approach to such simultaneous decision-making, this paper uses a continuous formulation and discusses the foundations of the procedure in greater detail. The method is demonstrated by a simple distributed design process for a DC motor, and the results are compared with those obtained for the same problem using sequential decision strategies in Krishnanet al. (1991).
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Experimental and applied acarology 19 (1995), S. 677-694 
    ISSN: 1572-9702
    Keywords: Hemisarcoptes ; Chilocorus ; mites ; parasitism ; phoresy ; tritium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Using tritium as a radiolabel marker of interspecific fluid transfer, we present experimental evidence that the heteromorphic deutonymph of an astigmatid mite (Hemisarcoptes cooremani) acquires materials (at least water) directly from the haemolymph of its beetle host (Chilocorus cacti). This acquisition is above that obtained from atmospheric vapour. The material acquired from the host is necessary for the completion of the ontogeny of H. cooremani and is likely procured through the action of the caudal ventral suckers of the heteromorphic deutonymph (hypopus). On gross morphological criteria, this mite-beetle relationship was previously defined as phoretic (for dispersal). Scanning electron photomicrographs of the physical relationship between the hypopodes and the heetles shed light on the ‘parasitic’ nature of the hypopus of H. cooremani. Our findings are discussed in terms of the evolution of parasitism from a free-living astigmatid form. This transition into parasitism is facilitated by the heteromorphic hypopus and represents a classic ‘wolf-insheep's-clothing’ strategy. The heteromorph retains the characteristic phoretic morphology while exploiting the host in transit.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1573-2711
    Keywords: titanium ; UHMWPE ; ion implantation ; Ti-6Al-4V ; wear
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Pin-on-disk sliding wear studies have been conducted on untreated and ion-implanted UHMWPE against an oxidised Ti-6Al-4V alloy. Under water lubricated conditions no wear was measured. The enhanced mechanical and physical properties of the surface treated materials are responsible for the improved wear performance which may be of great importance to orthopaedic prostheses.
    Type of Medium: Electronic Resource
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